World's Best Scientists 2026 revealed!
Karine Clément

Karine Clément

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Best Female Scientists
2025

D-Index & Metrics

Best Female Scientists

D-Index
138
Citations
74593
World Ranking
257
National Ranking
11

Medicine

D-Index
141
Citations
79710
World Ranking
1615
National Ranking
42

Research.com Recognitions

  • 2025 - Research.com Best Female Scientists Award

Overview

Karine Clément is affiliated with Sorbonne University in France and has contributed extensively to the fields of medicine and biochemistry, genetics, and molecular biology. Their research spans various subfields, including molecular biology, physiology, epidemiology, genetics, and surgery.

The primary topics of their research focus on gut microbiota and health, diet and metabolism studies, liver disease diagnosis and treatment, regulation of appetite and obesity, adipose tissue and metabolism, adipokines, inflammation, and metabolic diseases, as well as biochemical analysis and sensing techniques.

Karine Clément has authored publications in multiple prominent venues, frequently contributing to the following journals:

  • Journal of Hepatology
  • Nutrition Clinique et Métabolisme
  • Endocrine Abstracts
  • Gut Microbes
  • Obesity Surgery

Recent notable papers include:

  • "Gut microbiota-derived metabolites as central regulators in metabolic disorders," 2020, published in Gut
  • "Gut microbiota and human NAFLD: disentangling microbial signatures from metabolic disorders," 2020, published in Nature Reviews Gastroenterology & Hepatology
  • "Contemporary medical, device, and surgical therapies for obesity in adults," 2023, published in The Lancet
  • "Genome-wide association study of non-alcoholic fatty liver and steatohepatitis in a histologically characterised cohort," 2020, published in Journal of Hepatology
  • "Efficacy and safety of setmelanotide, an MC4R agonist, in individuals with severe obesity due to LEPR or POMC deficiency: single-arm, open-label, multicentre, phase 3 trials," 2020, published in The Lancet Diabetes & Endocrinology

Among frequent collaborators, Karine Clément has worked closely with Christine Poitou, Judith Aron-Wisnewsky, Pierre Bel Lassen, Eugeni Belda, and Laurent Genser, reflecting a network of scientific partnerships in the domain of metabolic and obesity research.

In addition to journal articles, Karine Clément has contributed to book publications, including a work titled "From Obesity to Diabetes," published by Springer Science+Business Media in 2022.

Best Publications

  • Richness of human gut microbiome correlates with metabolic markers

    Trine Nielsen;Junjie Qin;Edi Prifti

  • A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction

    Karine Clément;Christian Vaisse;Najiba Lahlou;Sylvie Cabrol

  • Dietary intervention impact on gut microbial gene richness

    Aurélie Cotillard;Aurélie Cotillard;Sean P. Kennedy;Ling Chun Kong;Ling Chun Kong;Edi Prifti;Edi Prifti;Edi Prifti

  • Akkermansia muciniphila and improved metabolic health during a dietary intervention in obesity: relationship with gut microbiome richness and ecology

    Maria Carlota Dao;Amandine Everard;Judith Aron-Wisnewsky;Nataliya Sokolovska

  • Differential adaptation of human gut microbiota to bariatric surgery-induced weight loss: links with metabolic and low-grade inflammation markers.

    Jean-Pierre Furet;Ling-Chun Kong;Julien Tap;Christine Poitou

  • Leptin regulation of bone resorption by the sympathetic nervous system and CART

    Florent Elefteriou;Jong Deok Ahn;Shu Takeda;Michael Starbuck

  • Reduction of macrophage infiltration and chemoattractant gene expression changes in white adipose tissue of morbidly obese subjects after surgery-induced weight loss.

    Raffaella Cancello;Corneliu Henegar;Nathalie Viguerie;Soraya Taleb

  • A frameshift mutation in human MC4R is associated with a dominant form of obesity

    Christian Vaisse;Karine Clement;Bernard Guy-Grand;Philippe Froguel

  • Dietary factors and low-grade inflammation in relation to overweight and obesity

    Philip C. Calder;Namanjeet Ahluwalia;Fred Brouns;Timo Buetler

  • Gut microbiota-derived metabolites as central regulators in metabolic disorders.

    Allison Agus;Karine Clément;Harry Sokol

  • Melanocortin-4 receptor mutations are a frequent and heterogeneous cause of morbid obesity

    Christian Vaisse;Karine Clement;Emmanuelle Durand;Serge Hercberg

  • Weight loss regulates inflammation-related genes in white adipose tissue of obese subjects

    Karine Clément;Nathalie Viguerie;Nathalie Viguerie;Christine Poitou;Claire Carette

  • Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice.

    Jian Liu;Adeline Divoux;Jiusong Sun;Jie Zhang

  • Close Linkage of Glucokinase Locus on Chromosome 7p to Early-Onset Non-Insulin-Dependent Diabetes Mellitus

    Ph. Froguel;M. Vaxillaire;F. Sun;G. Velho

  • Fibrosis and adipose tissue dysfunction.

    Kai Sun;Joan Tordjman;Karine Clément;Philipp E. Scherer

  • Genetic variation in the beta 3-adrenergic receptor and an increased capacity to gain weight in patients with morbid obesity.

    K. Clement;C. Vaisse;B. S. J. Manning;A. Basdevant

  • Histopathological algorithm and scoring system for evaluation of liver lesions in morbidly obese patients

    Pierre Bedossa;Christine Poitou;Christine Poitou;Nicolas Veyrie;Jean-Luc Bouillot

  • Elevated plasma ghrelin levels in Prader Willi syndrome.

    David E. Cummings;Karine Clement;Jonathan Q. Purnell;Christian Vaisse

  • Krüppel-like factor 4 regulates macrophage polarization

    Xudong Liao;Nikunj Sharma;Fehmida Kapadia;Guangjin Zhou

  • Increased Infiltration of Macrophages in Omental Adipose Tissue Is Associated With Marked Hepatic Lesions in Morbid Human Obesity

    Raffaella Cancello;Joan Tordjman;Christine Poitou;Gaël Guilhem

Frequent Co-Authors

Philippe Froguel
Philippe Froguel Imperial College London
Fredrik Bäckhed
Fredrik Bäckhed University of Gothenburg
Joël Doré
Joël Doré INRAE : Institut national de recherche pour l'agriculture, l'alimentation et l'environnement
Quentin M. Anstee
Quentin M. Anstee Newcastle University
Hannele Yki-Järvinen
Hannele Yki-Järvinen University of Helsinki
Christian Dina
Christian Dina University of Nantes

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