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Genetics

D-Index
68
Citations
12801
World Ranking
2457
National Ranking
1101

Overview

Vijaya Ramesh is affiliated with Harvard University in the United States, focusing on research at the intersection of medicine and molecular biology. Their work primarily addresses neurological and oncological disorders, especially neurofibromatosis, schwannoma, meningioma, and tuberous sclerosis complex.

Their extensive publication record includes contributions to fields such as medicine, biochemistry, genetics, molecular biology, neurology, molecular biology, epidemiology, physiology, and oncology. These diverse fields reflect the interdisciplinary nature of their investigations into complex neurological and cancer-related diseases.

Key topics covered in their research are:

  • Neurofibromatosis and Schwannoma Cases
  • Meningioma and schwannoma management
  • Tuberous Sclerosis Complex Research
  • Neuroblastoma Research and Treatments
  • Pluripotent Stem Cells Research
  • Chromatin Remodeling and Cancer
  • PI3K/AKT/mTOR signaling in cancer

Among their notable recent papers are:

  • TSC patient-derived isogenic neural progenitor cells reveal altered early neurodevelopmental phenotypes and rapamycin-induced MNK-eIF4E signaling, 2020, Molecular Autism
  • Brigatinib causes tumor shrinkage in both NF2-deficient meningioma and schwannoma through inhibition of multiple tyrosine kinases but not ALK, 2021, PLoS ONE
  • SMARCE1 deficiency generates a targetable mSWI/SNF dependency in clear cell meningioma, 2022, Nature Genetics
  • Gene therapy for tuberous sclerosis complex type 2 in a mouse model by delivery of AAV9 encoding a condensed form of tuberin, 2021, Science Advances
  • Combination therapy with mTOR kinase inhibitor and dasatinib as a novel therapeutic strategy for vestibular schwannoma, 2020, Scientific Reports

Ramesh frequently publishes in venues that include:

  • Molecular Autism
  • Scientific Reports
  • Neuro-Oncology Advances
  • Molecular Therapy - Methods & Clinical Development
  • Neuro-Oncology

Close collaboration is evident in their work with frequent co-authors such as:

  • Roberta L. Beauchamp
  • Scott R. Plotkin
  • Anat Stemmer-Rachamimov
  • Serkan Erdin
  • Shilpa Prabhakar

Best Publications

  • Reversal of learning deficits in a Tsc2+/− mouse model of tuberous sclerosis

    Dan Ehninger;Sangyeul Han;Carrie Shilyansky;Yu Zhou

  • The FERM domain: A unique module involved in the linkage of cytoplasmic proteins to the membrane

    Athar H. Chishti;Anthony C. Kim;Shirin M. Marfatia;Mohini Lutchman

  • Analysis of the neurofibromatosis 2 gene reveals molecular variants of meningioma.

    R. Wellenreuther;J. A. Kraus;D. Lenartz;A. G. Menon

  • NF2/Merlin Is a Novel Negative Regulator of mTOR Complex 1, and Activation of mTORC1 Is Associated with Meningioma and Schwannoma Growth

    Marianne James;S Han;Carolyn Polizzano;Scott Randall Plotkin

  • NHE-RF, a Regulatory Cofactor for Na+-H+Exchange, Is a Common Interactor for Merlin and ERM (MERM) Proteins

    Anita Murthy;Charo Gonzalez-Agosti;Etchell Cordero;Denise Pinney

  • Mutations in transcript isoforms of the neurofibromatosis 2 gene in multiple human tumour types.

    Bianchi Ab;Hara T;Ramesh;Gao J

  • Association of Mammalian Trp4 and Phospholipase C Isozymes with a PDZ Domain-containing Protein, NHERF

    Yufang Tang;Jisen Tang;Zhangguo Chen;Claudia Trost

  • The Nf2 tumor suppressor gene product is essential for extraembryonic development immediately prior to gastrulation.

    A I McClatchey;I Saotome;V Ramesh;J F Gusella

  • Mutant torsinA, responsible for early-onset torsion dystonia, forms membrane inclusions in cultured neural cells

    Jeffrey Hewett;Charo Gonzalez-Agosti;Damien Slater;Philipp Ziefer

  • Survey of somatic mutations in tuberous sclerosis complex (TSC) hamartomas suggests different genetic mechanisms for pathogenesis of TSC lesions.

    Yo Niida;Yo Niida;Anat O. Stemmer-Rachamimov;Marian Logrip;Dagmar Tapon

  • Functions of MUC16 in corneal epithelial cells.

    Timothy D Blalock;Sandra J Spurr-Michaud;Ann S Tisdale;Susan R Heimer

  • Analysis of the Neurofibromatosis 2 Gene in Human Ependymomas and Astrocytomas

    Mari Paz Rubio;Katia M. Correa;Vijaya Ramesh;Mia M. MacCollin

  • TorsinA protein and neuropathology in early onset generalized dystonia with GAG deletion.

    Kevin Rostasy;Sarah J. Augood;Jeffrey W. Hewett;Joanne Chung On Leung

  • Neuropathology and Molecular Genetics of Neurofibromatosis 2 and Related Tumors

    David N. Louis;Vijaya Ramesh;James F. Gusella

  • Mutational analysis of CDKN2 (MTS1/p16ink4) in human breast carcinomas.

    Lin Xu;Dennis Sgroi;Christopher J. Sterner;Roberta L. Beauchamp

  • Frequency and distribution of NF2 mutations in schwannomas

    Lee B. Jacoby;Mia MacCollin;Rosemary Barone;Vijaya Ramesh

  • Admixture Mapping of an Allele Affecting Interleukin 6 Soluble Receptor and Interleukin 6 Levels

    David Reich;David Reich;Nick Patterson;Vijaya Ramesh;Philip L. De Jager;Philip L. De Jager;Philip L. De Jager

  • Tenth International Workshop on Human Gene Mapping

    J.D. Tucker;M.L. Christensen;Av. Carrano;H.P. Wang

  • Genomic profiling distinguishes familial multiple and sporadic multiple meningiomas

    Yiping Shen;Fabio Nunes;Anat Stemmer-Rachamimov;Marianne James

  • Eighth International Workshop on Human Gene Mapping

    A.C. Chandley;P. Goetz;T.B. Hargreave;A.M. Joseph

Frequent Co-Authors

James F. Gusella
James F. Gusella Harvard University
David N. Louis
David N. Louis Harvard University
Xandra O. Breakefield
Xandra O. Breakefield Harvard University
David J. Kwiatkowski
David J. Kwiatkowski Brigham and Women's Hospital
Stephen J. Haggarty
Stephen J. Haggarty Harvard University
Andrea I. McClatchey
Andrea I. McClatchey Harvard University
Laurie J. Ozelius
Laurie J. Ozelius Harvard University
Michael E. Talkowski
Michael E. Talkowski Harvard University
Roger J. Packer
Roger J. Packer Children’s National Health System
Meena Upadhyaya
Meena Upadhyaya Cardiff University

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