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Biology and Biochemistry

D-Index
68
Citations
12461
World Ranking
7993
National Ranking
3617

Overview

Sylvie Breton is affiliated with Harvard University in the United States and has contributed extensively to research in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work spans multiple subfields including Physiology, Molecular Biology, Nephrology, Immunology, and Surgery.

The main topics explored in Breton's research include Adenosine and Purinergic Signaling, Acute Kidney Injury Research, Sperm and Testicular Function, Reproductive Biology and Fertility, Barrier Structure and Function Studies, Immune Response and Inflammation, and Reproductive System and Pregnancy.

Throughout their career, Breton has published in various scientific journals, with frequent contributions to:

  • Andrology
  • Cellular and Molecular Life Sciences
  • Journal of the American Society of Nephrology
  • Function
  • Human Reproduction

Recent notable papers by Breton include:

  • Sperm acquire epididymis-derived proteins through epididymosomes (2022, Human Reproduction)
  • Proinflammatory P2Y14 receptor inhibition protects against ischemic acute kidney injury in mice (2020, Journal of Clinical Investigation)
  • The contribution of inflammatory astrocytes to BBB impairments in a brain-chip model of Parkinson's disease (2023, Nature Communications)
  • From initial segment to cauda: a regional characterization of mouse epididymal CD11c+ mononuclear phagocytes based on immune phenotype and function (2020, American Journal of Physiology-Cell Physiology)
  • Alicyclic Ring Size Variation of 4-Phenyl-2-naphthoic Acid Derivatives as P2Y 14 Receptor Antagonists (2023, Journal of Medicinal Chemistry)

Sylvie Breton has collaborated frequently with a number of researchers, sharing authorship on multiple publications. Key coauthors include:

  • María Agustina Battistone
  • Christine Légaré
  • Alexandra C. Mendelsohn
  • Dennis Brown
  • Larissa Berloffa Belardin

Best Publications

  • Dedifferentiation of committed epithelial cells into stem cells in vivo

    Purushothama Rao Tata;Hongmei Mou;Ana Pardo-Saganta;Rui Zhao

  • Renal Vacuolar H+-ATPase

    Carsten A. Wagner;Karin E. Finberg;Sylvie Breton;Vladimir Marshansky

  • Acidification of the male reproductive tract by a proton pumping (H+)-ATPase.

    Sylvie Breton;Peter J.S. Smith;Ben Lui;Dennis Brown

  • Bicarbonate-regulated adenylyl cyclase (sAC) is a sensor that regulates pH-dependent V-ATPase recycling.

    Nuria Pastor-Soler;Valérie Beaulieu;Tatiana N. Litvin;Nicolas Da Silva

  • Nitric oxide and atrial natriuretic factor stimulate cGMP-dependent membrane insertion of aquaporin 2 in renal epithelial cells

    Richard Bouley;Sylvie Breton;Tian-xiao Sun;Margaret McLaughlin

  • Mitochondria-rich, proton-secreting epithelial cells.

    D Brown;S Breton

  • Regulation of Luminal Acidification by the V-ATPase

    Sylvie Breton;Dennis Brown

  • Transcriptomes of major renal collecting duct cell types in mouse identified by single-cell RNA-seq.

    Lihe Chen;Jae Wook Lee;Chung-Lin Chou;Anil V. Nair

  • Distinct Expression Patterns of Different Subunit Isoforms of the V-ATPase in the Rat Epididymis

    C. Pietrement;G.-H. Sun-Wada;N. Da Silva;M. Mckee

  • Transepithelial projections from basal cells are luminal sensors in pseudostratified epithelia

    Winnie Wai Chi Shum;Nicolas Da Silva;Mary McKee;Peter J.S. Smith

  • H(+)V-ATPase-dependent luminal acidification in the kidney collecting duct and the epididymis/vas deferens: vesicle recycling and transcytotic pathways.

    D Brown;S Breton

  • The Cellular Physiology of Carbonic Anhydrases

    Sylvie Breton

  • Aquaporin 9 Expression along the Male Reproductive Tract

    Nuria Pastor-Soler;Corinne Bagnis;Ivan Sabolic;Robert Tyszkowski

  • Regulation of the V-ATPase in kidney epithelial cells: dual role in acid–base homeostasis and vesicle trafficking

    Dennis Brown;Teodor G. Paunescu;Sylvie Breton;Vladimir Marshansky

  • The B1 subunit of the H+ATPase is a PDZ domain-binding protein. Colocalization with NHE-RF in renal B-intercalated cells.

    Sylvie Breton;Thorsten Wiederhold;Vladimir Marshansky;Ndona N. Nsumu

  • Regulation of luminal acidification in the male reproductive tract via cell-cell crosstalk.

    Winnie W. C. Shum;Nicolas Da Silva;Dennis Brown;Sylvie Breton

  • The B1-subunit of the H+ ATPase is required for maximal urinary acidification

    Karin E. Finberg;Carsten A. Wagner;Matthew A. Bailey;Teodor G. Păunescu

  • New insights into the regulation of V-ATPase-dependent proton secretion.

    Sylvie Breton;Dennis Brown

  • cAMP stimulates apical V-ATPase accumulation, microvillar elongation, and proton extrusion in kidney collecting duct A-intercalated cells

    Teodor G. Păunescu;Marija Ljubojevic;Leileata M. Russo;Christian Winter

  • Stimulation of AQP2 membrane insertion in renal epithelial cells in vitro and in vivo by the cGMP phosphodiesterase inhibitor sildenafil citrate (Viagra)

    Richard Bouley;Nuria Pastor-Soler;Ori Cohen;Margaret McLaughlin

Frequent Co-Authors

Dennis Brown
Dennis Brown Harvard University
Carsten A. Wagner
Carsten A. Wagner University of Zurich
Peter Smith
Peter Smith University of Aberdeen
Mark A. Knepper
Mark A. Knepper National Institutes of Health
Mikael J. Pittet
Mikael J. Pittet University of Geneva
Gerhard Giebisch
Gerhard Giebisch Yale University
John P. Geibel
John P. Geibel Yale University
Seth L. Alper
Seth L. Alper Beth Israel Deaconess Medical Center
Trairak Pisitkun
Trairak Pisitkun Chulalongkorn University
Seok Hyun Yun
Seok Hyun Yun Harvard University

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