D-Index & Metrics Best Publications

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Immunology D-index 60 Citations 10,678 144 World Ranking 1673 National Ranking 830
Genetics and Molecular Biology D-index 67 Citations 15,524 177 World Ranking 1720 National Ranking 878

Research.com Recognitions

Awards & Achievements

Member of the Association of American Physicians

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Immune system
  • DNA

His primary scientific interests are in Cell biology, B cell, Immunology, Bruton's tyrosine kinase and Tyrosine kinase. His Cell biology research integrates issues from Innate immune system and Biochemistry. His B cell research is multidisciplinary, incorporating elements of B-1 cell, Antigen-presenting cell and Immune system.

His work in Autoimmunity, Germinal center, Antibody, T cell and Antigen are all subfields of Immunology research. His Bruton's tyrosine kinase research includes themes of SH3 domain, Molecular biology and Kinase. His studies deal with areas such as Cancer research, Pleckstrin homology domain, Protein kinase A, Point mutation and Tyrosine phosphorylation as well as Tyrosine kinase.

His most cited work include:

  • Deficient expression of a B cell cytoplasmic tyrosine kinase in human X-linked agammaglobulinemia (1112 citations)
  • CD19+CD24hiCD38hi B Cells Exhibit Regulatory Capacity in Healthy Individuals but Are Functionally Impaired in Systemic Lupus Erythematosus Patients (1100 citations)
  • Mutation of unique region of Bruton's tyrosine kinase in immunodeficient XID mice. (772 citations)

What are the main themes of his work throughout his whole career to date?

Immunology, B cell, Molecular biology, Cell biology and Genetic enhancement are his primary areas of study. His Immunology research focuses on Immune system, Antibody, Autoimmunity, Antigen and Germinal center. His B cell study incorporates themes from T cell, Cancer research and Autoantibody.

The Molecular biology study combines topics in areas such as Haematopoiesis, Gene, Genome editing, Bruton's tyrosine kinase and Homology directed repair. His Cell biology research is multidisciplinary, incorporating perspectives in Transcription factor and T-cell receptor. The various areas that David J. Rawlings examines in his Genetic enhancement study include Virology, Viral vector, Stem cell and Severe combined immunodeficiency, In vivo.

He most often published in these fields:

  • Immunology (61.36%)
  • B cell (45.72%)
  • Molecular biology (38.94%)

What were the highlights of his more recent work (between 2018-2021)?

  • Antigen (16.81%)
  • Immunology (61.36%)
  • Antibody (20.06%)

In recent papers he was focusing on the following fields of study:

David J. Rawlings mostly deals with Antigen, Immunology, Antibody, Genome editing and Molecular biology. His biological study spans a wide range of topics, including Receptor and Disease. His Antibody research incorporates elements of Virus and Function.

His work deals with themes such as Haematopoiesis, Stem cell, Recombinant DNA and B-cell receptor, B cell, which intersect with Molecular biology. David J. Rawlings connects B cell with Translational elongation in his research. His Immune system research is multidisciplinary, incorporating elements of Phenotype and Cell biology.

Between 2018 and 2021, his most popular works were:

  • Functional SARS-CoV-2-Specific Immune Memory Persists after Mild COVID-19. (128 citations)
  • Therapeutically relevant engraftment of a CRISPR-Cas9-edited HSC-enriched population with HbF reactivation in nonhuman primates. (42 citations)
  • Therapeutically relevant engraftment of a CRISPR-Cas9-edited HSC-enriched population with HbF reactivation in nonhuman primates. (42 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Immune system

His primary areas of study are Immunology, Transplantation, Molecular biology, Receptor and Stem cell. His study in Antigen, Virus and Antibody is carried out as part of his studies in Immunology. The study incorporates disciplines such as Survival rate, Wiskott–Aldrich syndrome and Immunodeficiency in addition to Transplantation.

His research in Molecular biology intersects with topics in Reversion and Homology directed repair. The various areas that he examines in his Receptor study include T cell, Germinal center, Systemic lupus erythematosus, Interleukin 12 and Autoimmunity. His biological study spans a wide range of topics, including Humanized mouse, Fetal hemoglobin, Hereditary persistence of fetal hemoglobin and Transfection.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

CD19+CD24hiCD38hi B Cells Exhibit Regulatory Capacity in Healthy Individuals but Are Functionally Impaired in Systemic Lupus Erythematosus Patients

Paul A. Blair;Lina Yassin Noreña;Fabian Flores-Borja;David J. Rawlings.
Immunity (2010)

1453 Citations

Deficient expression of a B cell cytoplasmic tyrosine kinase in human X-linked agammaglobulinemia

Satoshi Tsukada;Douglas C. Saffran;David J. Rawlings;Ornella Parolini;Ornella Parolini.
Cell (1993)

1424 Citations

Mutation of unique region of Bruton's tyrosine kinase in immunodeficient XID mice.

D J Rawlings;D C Saffran;S Tsukada;D A Largaespada.
Science (1993)

940 Citations

Novel Suppressive Function of Transitional 2 B Cells in Experimental Arthritis

Jamie G. Evans;Karina A. Chavez-Rueda;Ayad Eddaoudi;Almut Meyer-Bahlburg.
Journal of Immunology (2007)

608 Citations

BTK/TEC KINASES REGULATE SUSTAINED INCREASES IN INTRACELLULAR CA2+ FOLLOWING B-CELL RECEPTOR ACTIVATION

Anne Catherine Fluckiger;Zuomei Li;Roberta M. Kato;Matthew I. Wahl.
The EMBO Journal (1998)

528 Citations

Activation of BTK by a Phosphorylation Mechanism Initiated by SRC Family Kinases

David J. Rawlings;Andrew M. Scharenberg;Hyunsun Park;Matthew I. Wahl.
Science (1996)

521 Citations

Phosphatidylinositol‐3,4,5‐trisphosphate (PtdIns‐3,4,5‐P3)/Tec kinase‐dependent calcium signaling pathway: a target for SHIP‐mediated inhibitory signals

Andrew M. Scharenberg;Ousama El-Hillal;David A. Fruman;Laurie O. Beitz.
The EMBO Journal (1998)

517 Citations

A Crucial Role for the p110δ Subunit of Phosphatidylinositol 3-Kinase in B Cell Development and Activation

Elizabeth Clayton;Giuseppe Bardi;Sarah E. Bell;David Chantry.
Journal of Experimental Medicine (2002)

513 Citations

Impaired expansion of mouse B cell progenitors lacking Btk

James D. Kerner;Mark W. Appleby;Randolph N. Mohr;Sylvia Chien.
Immunity (1995)

437 Citations

Regulation of Btk Function by a Major Autophosphorylation Site Within the SH3 Domain

Hyunsun Park;Matthew I Wahl;Daniel E.H Afar;Christoph W Turck.
Immunity (1996)

400 Citations

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