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Immunology

D-Index
84
Citations
26513
World Ranking
1368
National Ranking
702

Molecular Biology

D-Index
85
Citations
26467
World Ranking
852
National Ranking
449

Medicine

D-Index
85
Citations
26791
World Ranking
14599
National Ranking
7388

Research.com Recognitions

  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

David J. Rawlings is affiliated with Seattle Children's Hospital in the United States. Their research spans multiple interdisciplinary fields, primarily within medicine and immunology.

Their main fields of study include:

  • Medicine
  • Immunology and Microbiology
  • Biochemistry, Genetics and Molecular Biology

Subfields of study highlight focused research areas such as:

  • Immunology
  • Genetics
  • Molecular Biology
  • Oncology
  • Infectious Diseases

Key topics in their work cover:

  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology
  • CAR-T cell therapy research
  • Virus-based gene therapy research
  • CRISPR and Genetic Engineering
  • Immunodeficiency and Autoimmune Disorders
  • SARS-CoV-2 and COVID-19 Research

David J. Rawlings has contributed to several scientific journals and publication venues frequently, including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • The Journal of Immunology
  • The Journal of Experimental Medicine
  • Molecular Therapy - Methods & Clinical Development
  • Molecular Therapy

They have collaborated extensively with colleagues such as:

  • Richard G. James
  • Christopher D. Thouvenel
  • Marion Pepper
  • Jane H. Buckner
  • Jason Netland

Among recent publications are the following papers:

  • Functional SARS-CoV-2-Specific Immune Memory Persists after Mild COVID-19 (2020, Cell)
  • Excellent outcomes following hematopoietic cell transplantation for Wiskott-Aldrich syndrome: a PIDTC report (2020, Blood)
  • Functional SARS-CoV-2-specific immune memory persists after mild COVID-19 (2020, bioRxiv (Cold Spring Harbor Laboratory))
  • Individual and combined effects of the infrared, visible, and ultraviolet light components of solar radiation on damage biomarkers in human skin cells (2020, The FASEB Journal)
  • Multiplexed Functional Assessment of Genetic Variants in CARD11 (2020, The American Journal of Human Genetics)

David J. Rawlings is recognized as a member of the Association of American Physicians.

Best Publications

  • CD19+CD24hiCD38hi B Cells Exhibit Regulatory Capacity in Healthy Individuals but Are Functionally Impaired in Systemic Lupus Erythematosus Patients

    Paul A. Blair;Lina Yassin Noreña;Fabian Flores-Borja;David J. Rawlings

  • Deficient expression of a B cell cytoplasmic tyrosine kinase in human X-linked agammaglobulinemia

    Satoshi Tsukada;Douglas C. Saffran;David J. Rawlings;Ornella Parolini;Ornella Parolini

  • Mutation of unique region of Bruton's tyrosine kinase in immunodeficient XID mice

    David J. Rawlings;Douglas C. Saffran;Satoshi Tsukada;David A. Largaespada

  • Functional SARS-CoV-2-Specific Immune Memory Persists after Mild COVID-19.

    Lauren B. Rodda;Jason Netland;Laila Shehata;Kurt B. Pruner

  • Novel Suppressive Function of Transitional 2 B Cells in Experimental Arthritis

    Jamie G. Evans;Karina A. Chavez-Rueda;Ayad Eddaoudi;Almut Meyer-Bahlburg

  • A Crucial Role for the p110δ Subunit of Phosphatidylinositol 3-Kinase in B Cell Development and Activation

    Elizabeth Clayton;Giuseppe Bardi;Sarah E. Bell;David Chantry

  • Activation of BTK by a Phosphorylation Mechanism Initiated by SRC Family Kinases

    David J. Rawlings;Andrew M. Scharenberg;Hyunsun Park;Matthew I. Wahl

  • Phosphatidylinositol-3,4,5-trisphosphate (PtdIns-3,4,5-P3)/Tec kinase-dependent calcium signaling pathway: a target for SHIP-mediated inhibitory signals

    Andrew M. Scharenberg;Ousama El-Hillal;David A. Fruman;Laurie O. Beitz

  • BTK/TEC KINASES REGULATE SUSTAINED INCREASES IN INTRACELLULAR CA2+ FOLLOWING B-CELL RECEPTOR ACTIVATION

    Anne Catherine Fluckiger;Zuomei Li;Roberta M. Kato;Matthew I. Wahl

  • PKC-beta controls I kappa B kinase lipid raft recruitment and activation in response to BCR signaling.

    Thomas T. Su;Beichu Guo;Yuko Kawakami;Karen Sommer

  • Regulation of Btk Function by a Major Autophosphorylation Site Within the SH3 Domain

    Hyunsun Park;Matthew I Wahl;Daniel E.H Afar;Christoph W Turck

  • Impaired expansion of mouse B cell progenitors lacking Btk

    James D. Kerner;Mark W. Appleby;Randolph N. Mohr;Sylvia Chien

  • Integration of B cell responses through Toll-like receptors and antigen receptors

    David J. Rawlings;Marc A. Schwartz;Shaun W. Jackson;Almut Meyer-Bahlburg

  • Phosphorylation of the CARMA1 Linker Controls NF-κB Activation

    Karen Sommer;Beichu Guo;Joel L. Pomerantz;Ashok D. Bandaranayake

  • IL-10 Deficiency Unleashes an Influenza-Specific Th17 Response and Enhances Survival against High-Dose Challenge

    K. Kai McKinstry;Tara M. Strutt;Amanda Buck;Jonathan D. Curtis

  • Integration with the human genome of peptide sequences obtained by high-throughput mass spectrometry

    Frank Desiere;Eric W Deutsch;Alexey I Nesvizhskii;Parag Mallick

  • Tracking genome engineering outcome at individual DNA breakpoints

    Michael T. Certo;Byoung Y. Ryu;James E. Annis;Mikhail Garibov

  • Transitional B Lymphocyte Subsets Operate as Distinct Checkpoints in Murine Splenic B Cell Development

    Thomas T. Su;David J. Rawlings

  • Altered B cell signalling in autoimmunity

    David J. Rawlings;Genita Metzler;Genita Metzler;Michelle Wray-Dutra;Michelle Wray-Dutra;Shaun W. Jackson;Shaun W. Jackson

  • Engagement of the human pre-B cell receptor generates a lipid raft-dependent calcium signaling complex.

    Beichu Guo;Roberta M Kato;Maria Garcia-Lloret;Matthew I Wahl

  • BTK Regulates PtdIns-4,5-P2 Synthesis: Importance for Calcium Signaling and PI3K Activity

    Kan Saito;Kimberley F. Tolias;Abdelhafid Saci;Henry B. Koon

Frequent Co-Authors

Andrew M. Scharenberg
Andrew M. Scharenberg Seattle Children's Hospital
Troy R. Torgerson
Troy R. Torgerson Allen Institute
Hans Peter Kiem
Hans Peter Kiem Fred Hutchinson Cancer Research Center
Hans D. Ochs
Hans D. Ochs University of Washington
Owen N. Witte
Owen N. Witte University of California, Los Angeles
Jane H. Buckner
Jane H. Buckner Virginia Mason Medical Center
Steven F. Ziegler
Steven F. Ziegler Virginia Mason Medical Center
Mohamed Oukka
Mohamed Oukka University of Washington
Charles E. Alpers
Charles E. Alpers University of Washington
Toshiaki Kawakami
Toshiaki Kawakami University of California, San Diego

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