Owen N. Witte

Research.com Recognitions

• 1997 - Member of the National Academy of Sciences
• 1996 - Fellow of the American Academy of Arts and Sciences

Overview

Best Publications

• Tyrosine kinase activity and transformation potency of bcr-abl oncogene products.

  Tracy G. Lugo;Ann-Marie Pendergast;Alexander J. Muller;Owen N. Witte

  1725
  Citations

• Deficient expression of a B cell cytoplasmic tyrosine kinase in human X-linked agammaglobulinemia

  Satoshi Tsukada;Douglas C. Saffran;David J. Rawlings;Ornella Parolini;Ornella Parolini

  1595
  Citations

• An alteration of the human c-abl protein in K562 leukemia cells unmasks associated tyrosine kinase activity

  James B. Konopka;Susan M. Watanabe;Owen N. Witte

  1258
  Citations

• Mutation of unique region of Bruton's tyrosine kinase in immunodeficient XID mice

  David J. Rawlings;Douglas C. Saffran;Satoshi Tsukada;David A. Largaespada

  1047
  Citations

• The chronic myelogenous leukemia-specific P210 protein is the product of the bcr/abl hybrid gene.

  Yinon Ben-Neriah;George Q. Daley;Anne-Marie Mes-Masson;Owen N. Witte

  1045
  Citations

• Prostate stem cell antigen: A cell surface marker overexpressed in prostate cancer

  Robert E. Reiter;Zhennen Gu;Tetsuro Watabe;George Thomas

  992
  Citations

• Diagnosis of chronic myeloid and acute lymphocytic leukemias by detection of leukemia-specific mRNA sequences amplified in vitro.

  Ernest S. Kawasaki;Steven S. Clark;Mazie Y. Coyne;Stephen D. Smith

  918
  Citations

• Long-term culture of B lymphocytes and their precursors from murine bone marrow.

  Cheryl A. Whitlock;Owen N. Witte

  828
  Citations

• Identification of a Cell of Origin for Human Prostate Cancer

  Andrew S. Goldstein;Jiaoti Huang;Changyong Guo;Isla P. Garraway

  700
  Citations

• Differential expression of myc family genes during murine development

  Kathryn A. Zimmerman;George D. Yancopoulos;Robert G. Collum;Russell K. Smith

  698
  Citations

• Steel locus defines new multipotent growth factor.

  Owen N. Witte

  686
  Citations

• Induction of a chronic myelogenous leukemia-like syndrome in mice with v-abl and BCR/ABL

  Michelle A. Kelliher;Jami McLaughlin;Owen N. Witte;Naomi Rosenberg

  672
  Citations

• Multistep synthesis of a radiolabeled imaging probe using integrated microfluidics.

  Chung-Cheng Lee;Guodong Sui;Arkadij Elizarov;Chengyi Jenny Shu

  670
  Citations

• Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer.

  David A. Quigley;Ha X. Dang;Shuang G. Zhao;Paul Lloyd

  651
  Citations

• Clinical and Genomic Characterization of Treatment-Emergent Small-Cell Neuroendocrine Prostate Cancer: A Multi-institutional Prospective Study

  Rahul Aggarwal;Jiaoti Huang;Joshi J. Alumkal;Li Zhang

  645
  Citations

• Prostate stem cell antigen (PSCA) expression increases with high gleason score, advanced stage and bone metastasis in prostate cancer.

  Gu Z;Thomas G;Yamashiro J;Shintaku Ip

  622
  Citations

• Abelson murine leukaemia virus protein is phosphorylated in vitro to form phosphotyrosine.

  Owen N. Witte;Asim Dasgupta;David Baltimore

  615
  Citations

• Dominant negative MYC blocks transformation by ABL oncogenes

  Charles L. Sawyers;Wendy Callahan;Owen N. Witte

  577
  Citations

• Structure of the Abelson murine leukemia virus genome and the homologous cellular gene: Studies with cloned viral DNA

  Stephen P. Goff;Eli Gilboa;Owen N. Witte;David Baltimore

  568
  Citations

• The BCR-ABL Story: Bench to Bedside and Back

  Stephane Wong;Owen N Witte

  550
  Citations