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Immunology

D-Index
73
Citations
19150
World Ranking
2139
National Ranking
1041

Overview

Jane H. Buckner is affiliated with Virginia Mason Medical Center in the United States. Their research spans multiple fields, primarily focusing on Medicine and Immunology and Microbiology. Within these broader disciplines, their subfields of study include Immunology, Rheumatology, Molecular Biology, Genetics, and Radiology, Nuclear Medicine and Imaging.

The scientist's research covers several main topics, including:

  • T-cell and B-cell Immunology
  • Immune Cell Function and Interaction
  • Systemic Lupus Erythematosus Research
  • Diabetes and associated disorders
  • Monoclonal and Polyclonal Antibodies Research
  • Rheumatoid Arthritis Research and Therapies
  • Pancreatic function and diabetes

Jane H. Buckner has contributed to a number of recent publications, highlighting ongoing research in immunology, diabetes, and arthritis. Notable papers include:

  • "Notch signalling drives synovial fibroblast identity and arthritis pathology" (2020), published in Nature
  • "Fine-mapping, trans-ancestral and genomic analyses identify causal variants, cells, genes and drug targets for type 1 diabetes" (2021), published in Nature Genetics
  • "Immunotherapy: Building a bridge to a cure for type 1 diabetes" (2021), published in Science
  • "Neutrophil extracellular traps mediate articular cartilage damage and enhance cartilage component immunogenicity in rheumatoid arthritis" (2020), published in JCI Insight
  • "Clonal IgA and IgG autoantibodies from individuals at risk for rheumatoid arthritis identify an arthritogenic strain of Subdoligranulum" (2022), published in Science Translational Medicine

The frequent co-authors who have collaborated with Jane H. Buckner across many projects include:

  • Cate Speake
  • V. Michael Holers
  • Kevin D. Deane
  • Eddie A. James
  • Troy R. Torgerson

The scientist frequently publishes in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • The Journal of Immunology
  • Annals of the Rheumatic Diseases
  • Science Translational Medicine
  • JCI Insight

Best Publications

  • Induction of FoxP3 and acquisition of T regulatory activity by stimulated human CD4 + CD25 – T cells

    Mindi R.Walker;Deborah J. Kasprowicz;Vivian H. Gersuk;Angéle Bènard

  • Type 1 diabetes immunotherapy using polyclonal regulatory T cells.

    Jeffrey A. Bluestone;Jane H. Buckner;Mark Fitch;Stephen E. Gitelman

  • Mechanisms of impaired regulation by CD4+CD25+FOXP3+ regulatory T cells in human autoimmune diseases

    Jane Hoyt Buckner

  • Complement receptor 2/CD21- human naive B cells contain mostly autoreactive unresponsive clones

    Isabelle Isnardi;Yen Shing Ng;Laurence Menard;Greta Meyers

  • Genetic Variation in PTPN22 Corresponds to Altered Function of T and B Lymphocytes

    Mary Rieck;Adrian Arechiga;Suna Onengut-Gumuscu;Carla Greenbaum

  • The effector T cells of diabetic subjects are resistant to regulation via CD4+ FOXP3+ regulatory T cells.

    Anya Schneider;Mary Rieck;Srinath Sanda;Catherine Pihoker

  • Rheumatoid arthritis and the mucosal origins hypothesis: protection turns to destruction.

    V. Michael Holers;M. Kristen Demoruelle;Kristine A. Kuhn;Jane H. Buckner

  • De novo generation of antigen-specific CD4+CD25+ regulatory T cells from human CD4+CD25- cells.

    Mindi R. Walker;Bryan D. Carson;Gerald T. Nepom;Steven F. Ziegler

  • CD4+FOXP3+ T Regulatory Cells in Human Autoimmunity: More Than a Numbers Game

    S. Alice Long;Jane H. Buckner

  • Rapamycin/IL-2 Combination Therapy in Patients With Type 1 Diabetes Augments Tregs yet Transiently Impairs β-Cell Function

    S. Alice Long;Mary Rieck;Srinath Sanda;Jennifer B. Bollyky

  • The PTPN22 allele encoding an R620W variant interferes with the removal of developing autoreactive B cells in humans

    Laurence Menard;David Saadoun;Isabelle Isnardi;Yen Shing Ng

  • Defects in IL-2R Signaling Contribute to Diminished Maintenance of FOXP3 Expression in CD4+CD25+ Regulatory T-Cells of Type 1 Diabetic Subjects

    S. Alice Long;Karen Cerosaletti;Paul L. Bollyky;Megan Tatum

  • Low-dose interleukin-2 fosters a dose-dependent regulatory T cell tuned milieu in T1D patients.

    Michelle Rosenzwajg;Guillaume Churlaud;Roberto Mallone;Adrien Six

  • Synovial fibroblast-neutrophil interactions promote pathogenic adaptive immunity in rheumatoid arthritis.

    Carmelo Carmona-Rivera;Philip M. Carlucci;Erica Moore;Nithya Lingampalli;Nithya Lingampalli

  • Porphyromonas gingivalis and Disease-Related Autoantibodies in Individuals at Increased Risk of Rheumatoid Arthritis

    Ted R Mikuls;Geoffrey Milton Thiele;Kevin D. Deane;Jeffrey B Payne

  • Fine-mapping, trans-ancestral and genomic analyses identify causal variants, cells, genes and drug targets for type 1 diabetes.

    C C Robertson;Inshaw Jrj.;S Onengut-Gumuscu;Chen W-M.

  • Cutting Edge: The PTPN22 Allelic Variant Associated with Autoimmunity Impairs B Cell Signaling

    Adrian F. Arechiga;Tania Habib;Yantao He;Xian Zhang

  • B cell–derived IL-6 initiates spontaneous germinal center formation during systemic autoimmunity

    Tanvi Arkatkar;Samuel W. Du;Holly M. Jacobs;Elizabeth M. Dam

  • Citrulline-Specific Th1 Cells Are Increased in Rheumatoid Arthritis and Their Frequency Is Influenced by Disease Duration and Therapy

    Eddie A. James;Mary Rieck;Jennifer Pieper;John A. Gebe

  • FOXP3 and the regulation of Treg/Th17 differentiation.

    Steven F. Ziegler;Jane H. Buckner

  • Induction of FoxP3 and acquisition of T regulatory activity by stimulated

    Deborah J. Kasprowicz;Vivian H. Gersuk;Angéle Bènard;Megan Van Landeghen

Frequent Co-Authors

Gerald T. Nepom
Gerald T. Nepom Virginia Mason Medical Center
Carla J. Greenbaum
Carla J. Greenbaum Virginia Mason Medical Center
David J. Rawlings
David J. Rawlings Seattle Children's Hospital
V. Michael Holers
V. Michael Holers University of Colorado Denver
Eddie A. James
Eddie A. James Virginia Mason Medical Center
Jill M. Norris
Jill M. Norris University of Colorado Anschutz Medical Campus
Michael H. Weisman
Michael H. Weisman Cedars-Sinai Medical Center
Peter K. Gregersen
Peter K. Gregersen Feinstein Institute for Medical Research
William H. Robinson
William H. Robinson Stanford University
Steven F. Ziegler
Steven F. Ziegler Virginia Mason Medical Center

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