World's Best Scientists 2026 revealed!
David Klatzmann

David Klatzmann

D-Index & Metrics

Immunology

D-Index
99
Citations
36800
World Ranking
748
National Ranking
23

Medicine

D-Index
99
Citations
36925
World Ranking
8582
National Ranking
262

Overview

David Klatzmann is affiliated with Sorbonne University in France and has contributed extensively to the fields of Medicine and Immunology and Microbiology. Their research spans several subfields, including Immunology, Rheumatology, Oncology, Molecular Biology, and Genetics.

The scientist's main topics of work include:

  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology
  • Systemic Lupus Erythematosus Research
  • Atherosclerosis and Cardiovascular Diseases
  • Immunotherapy and Immune Responses
  • Tryptophan and brain disorders
  • IL-33, ST2, and ILC Pathways

Their recent scholarly output includes several papers of note:

  • "Cross-reactivity between tumor MHC class I-restricted antigens and an enterococcal bacteriophage," 2020, published in Science
  • "A microbiota-modulated checkpoint directs immunosuppressive intestinal T cells into cancers," 2023, published in Science
  • "Abatacept/Ruxolitinib and Screening for Concomitant Respiratory Muscle Failure to Mitigate Fatality of Immune-Checkpoint Inhibitor Myocarditis," 2023, published in Cancer Discovery
  • "Polyclonal expansion of TCR Vβ 21.3 + CD4 + and CD8 + T cells is a hallmark of multisystem inflammatory syndrome in children," 2021, published in Science Immunology
  • "Immune checkpoint inhibitor-induced myositis, the earliest and most lethal complication among rheumatic and musculoskeletal toxicities," 2020, published in Autoimmunity Reviews

David Klatzmann frequently collaborates with other researchers, including:

  • Michèlle Rosenzwajg
  • Encarnita Mariotti-Ferrandiz
  • Nicolas Tchitchek
  • P. Cacoub
  • David Saadoun

They have published numerous works in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Annals of the Rheumatic Diseases
  • La Revue de Médecine Interne
  • Journal of Autoimmunity
  • Osteoarthritis and Cartilage

David Klatzmann's research reflects a multidisciplinary approach with a strong emphasis on immunological mechanisms and their implications across various diseases. Their work touches on fundamental immune cell interactions as well as clinical complications related to immune checkpoint inhibitors and systemic diseases.

Best Publications

  • T-lymphocyte T4 molecule behaves as the receptor for human retrovirus LAV

    David Klatzmann;Eric Champagne;Sophie Chamaret;Jacqueline Gruest

  • Natural regulatory T cells control the development of atherosclerosis in mice.

    Hafid Ait-Oufella;Benoît L Salomon;Stéphane Potteaux;Anna-Karin L Robertson

  • Selective tropism of lymphadenopathy associated virus (LAV) for helper-inducer T lymphocytes.

    D Klatzmann;F Barré-Sinoussi;M T Nugeyre;C Danquet

  • CD4(+)CD25(+) immunoregulatory T Cells: new therapeutics for graft-versus-host disease

    José L. Cohen;Aurélie Trenado;Douglas Vasey;David Klatzmann

  • Regulatory T-cell responses to low-dose interleukin-2 in HCV-induced vasculitis.

    David Saadoun;Michelle Rosenzwajg;Florence Joly;Adrien Six

  • Nucleotide sequence of the visna lentivirus: relationship to the AIDS virus.

    Pierre Sonigo;Marc Alizon;Katherine Staskus;David Klatzmann

  • The promise of low-dose interleukin-2 therapy for autoimmune and inflammatory diseases

    David Klatzmann;Abul K. Abbas

  • Continuous Activation of Autoreactive CD4+ CD25+ Regulatory T Cells in the Steady State

    Sylvain Fisson;Guillaume Darrasse-Jèze;Elena Litvinova;Franck Septier

  • Recipient-type specific CD4+CD25+ regulatory T cells favor immune reconstitution and control graft-versus-host disease while maintaining graft-versus-leukemia.

    Aurélie Trenado;Frédéric Charlotte;Sylvain Fisson;Micael Yagello

  • Regression of established macroscopic liver metastases after in situ transduction of a suicide gene.

    Manuel Caruso;Yves Panis;Singh Gagandeep;Didier Houssin

  • A novel dendritic cell subset involved in tumor immunosurveillance.

    Julien Taieb;Nathalie Chaput;Cédric Ménard;Lionel Apetoh

  • Bone Marrow Mesenchymal Stem Cells Suppress Lymphocyte Proliferation In Vitro but Fail to Prevent Graft-versus-Host Disease in Mice

    Muriel Sudres;Françoise Norol;Aurélie Trenado;Sylvie Grégoire

  • IL-2 reverses established type 1 diabetes in NOD mice by a local effect on pancreatic regulatory T cells

    Yenkel Grinberg-Bleyer;Audrey Baeyens;Sylvaine You;Rima Elhage

  • Dendritic cells are required for the development of chronic eosinophilic airway inflammation in response to inhaled antigen in sensitized mice

    Bart N. Lambrecht;Benoı̂t Salomon;David Klatzmann;Romain A. Pauwels

  • Adaptation of Lymphadenopathy Associated Virus (LAV) to Replication in EBV-Transformed B Lymphoblastoid Cell Lines

    L. Montagnier;J. Gruest;S. Chamaret;C. Dauguet

  • Low-dose interleukin 2 in patients with type 1 diabetes: a phase 1/2 randomised, double-blind, placebo-controlled trial

    Agnès Hartemann;Gilbert Bensimon;Christine A Payan;Sophie Jacqueminet

  • Chronic brain inflammation and persistent herpes simplex virus 1 thymidine kinase expression in survivors of syngeneic glioma treated by adenovirus-mediated gene therapy: implications for clinical trials.

    R. A. Dewey;G. Morrissey;C. M. Cowsill;D. Stone

  • Immunological and clinical effects of low-dose interleukin-2 across 11 autoimmune diseases in a single, open clinical trial

    Michelle Rosenzwajg;Roberta Lorenzon;Patrice Cacoub;Hang Phuong Pham

  • A Phase I/II Study of Herpes Simplex Virus Type 1 Thymidine Kinase "Suicide" Gene Therapy for Recurrent Glioblastoma

    David Klatzmann;Charles A. Valéry;Gilbert Bensimon;Beatrice Marro

  • Cross-reactivity between tumor MHC class I-restricted antigens and an enterococcal bacteriophage.

    Aurélie Fluckiger;Aurélie Fluckiger;Romain Daillère;Romain Daillère;Mohamed Sassi;Barbara Susanne Sixt

  • Identification of CD8+CD25+Foxp3+ suppressive T cells in colorectal cancer tissue

    nathalie chaput;Samy Louafi;armelle Bardier;frederic charlotte

Frequent Co-Authors

Michelle Rosenzwajg
Michelle Rosenzwajg Sorbonne University
Benoît L. Salomon
Benoît L. Salomon Sorbonne University
Patrice Cacoub
Patrice Cacoub Sorbonne University
David Saadoun
David Saadoun Université Paris Cité
Luc Montagnier
Luc Montagnier Institut Pasteur
Olivier Benveniste
Olivier Benveniste Sorbonne University
Olivier Boyer
Olivier Boyer University of Rouen
Lucile Musset
Lucile Musset Sorbonne University
Frédéric Charlotte
Frédéric Charlotte Université Paris Cité
Maria G. Castro
Maria G. Castro University of Michigan–Ann Arbor

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