William W. Kwok

Overview

Best Publications

• A phenotypically and functionally distinct human TH2 cell subpopulation is associated with allergic disorders

  Erik Wambre;Veronique Bajzik;Jonathan H. DeLong;Kimberly O’Brien

  392
  Citations

• Disease-associated Bias in T Helper Type 1 (Th1)/Th2 CD4+ T Cell Responses Against MAGE-6 in HLA-DRB10401+ Patients With Renal Cell Carcinoma or Melanoma

  Tomohide Tatsumi;Lisa S. Kierstead;Elena Ranieri;Elena Ranieri;Loreto Gesualdo

  362
  Citations

• Functional inflammatory profiles distinguish myelin-reactive T cells from patients with multiple sclerosis

  Yonghao Cao;Brittany A. Goods;Khadir Raddassi;Gerald T. Nepom

  333
  Citations

• Antibiotic-refractory Lyme arthritis is associated with HLA-DR molecules that bind a Borrelia burgdorferi peptide

  Allen C. Steere;William Klitz;William Klitz;Elise E. Drouin;Ben A. Falk

  266
  Citations

• Molecular Basis for HLA-DQ Associations With IDDM

  Gerald T Nepom;William W Kwok

  253
  Citations

• Differentiation stage determines pathologic and protective allergen-specific CD4+ T-cell outcomes during specific immunotherapy.

  Erik Wambre;Jonathan H. DeLong;Eddie A. James;Rebecca E. LaFond

  221
  Citations

• Allele-specific motifs characterize HLA-DQ interactions with a diabetes-associated peptide derived from glutamic acid decarboxylase.

  William W. Kwok;Mary Ellen Domeier;Fenella C. Raymond;Patricia Byers

  203
  Citations

• Recognition of Posttranslationally Modified GAD65 Epitopes in Subjects With Type 1 Diabetes

  John W. McGinty;I-Ting Chow;Carla Greenbaum;Jared Odegard

  195
  Citations

• HLA-DQ Tetramers Identify Epitope-Specific T Cells in Peripheral Blood of Herpes Simplex Virus Type 2-Infected Individuals: Direct Detection of Immunodominant Antigen-Responsive Cells

  William W. Kwok;Andrew W. Liu;Erik J. Novak;John A. Gebe

  188
  Citations

• Healthy Human Subjects Have CD4+ T Cells Directed against H5N1 Influenza Virus

  Michelle Roti;Junbao Yang;DeAnna Berger;Laurie Huston

  184
  Citations

• Ara h 1–reactive T cells in individuals with peanut allergy

  Jonathan H. DeLong;Kelly Hetherington Simpson;Erik Wambre;Eddie A. James

  178
  Citations

• Comparative study of GAD65-specific CD4+ T cells in healthy and type 1 diabetic subjects

  Nancy A. Danke;Junbao Yang;Carla Greenbaum;William W. Kwok;William W. Kwok

  173
  Citations

• Autoreactive T cells specific for insulin B:11-23 recognize a low-affinity peptide register in human subjects with autoimmune diabetes.

  Junbao Yang;I-Ting Chow;Tomasz Sosinowski;Nadia Torres-Chinn

  160
  Citations

• Islet-specific glucose-6-phosphatase catalytic subunit-related protein-reactive CD4+ T cells in human subjects.

  Junbao Yang;Nancy A. Danke;DeAnna Berger;Sandra Reichstetter

  158
  Citations

• CD8 CTL from genital herpes simplex lesions: recognition of viral tegument and immediate early proteins and lysis of infected cutaneous cells.

  David M. Koelle;Hongbo B. Chen;Marc A. Gavin;Anna Wald

  157
  Citations

• Specific immunotherapy modifies allergen-specific CD4+ T-cell responses in an epitope-dependent manner

  Erik Wambre;Jonathan H. DeLong;Eddie A. James;Nadia Torres-Chinn

  156
  Citations

• HLA-DQ allelic polymorphisms constrain patterns of class II heterodimer formation.

  William W. Kwok;Susan Kovats;Philip Thurtle;Gerald T. Nepom

  155
  Citations

• DNA from the A6S/2 crown gall tumor contains scrambled Ti-plasmid sequences near its junctions with plant DNA

  Robert B. Simpson;Robert B. Simpson;Patrick J. O'Hara;William Kwok;Alice L. Montoya

  149
  Citations

• MHC II tetramers visualize human CD4+ T cell responses to Epstein-Barr virus infection and demonstrate atypical kinetics of the nuclear antigen EBNA1 response.

  Heather M. Long;Odette L. Chagoury;Alison M. Leese;Gordon B. Ryan

  140
  Citations

• CD4+ T cells from type 1 diabetic and healthy subjects exhibit different thresholds of activation to a naturally processed proinsulin epitope.

  Junbao Yang;Nancy Danke;Michelle Roti;Laurie Huston

  138
  Citations

• Generation of high quantities of viral and tumor-specific human CD4+ and CD8+ T-cell clones using peptide pulsed mature dendritic cells.

  Jean-François Fonteneau;Marie Larsson;Selin Somersan;Catherine Sanders

  135
  Citations