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Biology and Biochemistry

D-Index
57
Citations
12503
World Ranking
13777
National Ranking
5830

Overview

Joseph Chappell is affiliated with the University of Kentucky in the United States. Their research focuses on areas within medicine, biochemistry, genetics, and molecular biology, with particular attention to pharmacology, molecular biology, and neurology.

The scientist has contributed to topics including:

  • Cannabis and Cannabinoid Research
  • Heme Oxygenase-1 and Carbon Monoxide
  • Intracerebral and Subarachnoid Hemorrhage Research

One recent publication by Joseph Chappell is titled Cannabidiol's Multifactorial Mechanisms Has Therapeutic Potential for Aneurysmal Subarachnoid Hemorrhage: a Review, published in 2022 in Translational Stroke Research. This work addresses the therapeutic potential of cannabidiol in the context of aneurysmal subarachnoid hemorrhage.

Frequent co-authors collaborating with Joseph Chappell include:

  • Nicholas Henry
  • Justin F. Fraser
  • Tamra Langley
  • Jill Roberts

The primary venue for publication has been Translational Stroke Research, reflecting focus in stroke and neurological research fields.

Best Publications

  • Structural Basis for Cyclic Terpene Biosynthesis by Tobacco 5-Epi-Aristolochene Synthase

    Courtney M. Starks;Kyoungwhan Back;Kyoungwhan Back;Joseph Chappell;Joseph Chappell;Joseph P. Noel;Joseph P. Noel

  • Biochemistry and Molecular Biology of the Isoprenoid Biosynthetic Pathway in Plants

    Joseph Chappell

  • Transcription of plant defence genes in response to UV light or fungal elicitor

    Joseph Chappell;Joseph Chappell;Joseph Chappell;Klaus Hahlbrock;Klaus Hahlbrock

  • Redirection of cytosolic or plastidic isoprenoid precursors elevates terpene production in plants.

    Shuiqin Wu;Michel Schalk;Anthony Clark;R Brandon Miles

  • Alternatively spliced vascular endothelial growth factor receptor-2 is an essential endogenous inhibitor of lymphatic vessel growth

    Romulo J C Albuquerque;Takahiko Hayashi;Won Gil Cho;Mark E Kleinman

  • The Biochemistry and Molecular Biology of Isoprenoid Metabolism

    Joseph Chappell

  • Is the Reaction Catalyzed by 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase a Rate-Limiting Step for Isoprenoid Biosynthesis in Plants?

    J. Chappell;F. Wolf;J. Proulx;R. Cuellar

  • Gene family for an elicitor-induced sesquiterpene cyclase in tobacco

    Peter J. Facchini;Joseph Chappell

  • Isoprenoid biosynthesis in plants: carbon partitioning within the cytoplasmic pathway

    Jeffrey D. Newman;Joseph Chappell

  • Induction of phenylalanine ammonia-lyase and 4-coumarate:CoA ligase mRNAs in cultured plant cells by UV light or fungal elicitor

    David N. Kuhn;Joseph Chappell;Alain Boudet;Klaus Hahlbrock

  • Induction of Sesquiterpene Cyclase and Suppression of Squalene Synthetase Activities in Plant Cell Cultures Treated with Fungal Elicitor

    Urs Vögeli;Joseph Chappell

  • Identifying and manipulating structural determinates linking catalytic specificities in terpene synthases

    Bryan T. Greenhagen;Paul E. O’Maille;Joseph P. Noel;Joe Chappell

  • The diverse sesquiterpene profile of patchouli, Pogostemon cablin, is correlated with a limited number of sesquiterpene synthases

    Fabienne Deguerry;Laurence Pastore;Shuiqin Wu;Anthony Clark

  • Quantitative exploration of the catalytic landscape separating divergent plant sesquiterpene synthases

    Paul E O'Maille;Arthur Malone;Nikki Dellas;Nikki Dellas;B Andes Hess

  • Cloning and Bacterial Expression of a Sesquiterpene Cyclase from Hyoscyamus muticus and Its Molecular Comparison to Related Terpene Cyclases (

    Kyoungwhan Back;Joseph Chappell

  • Induction of sesquiterpenoid biosynthesis in tobacco cell suspension cultures by fungal elicitor.

    Joseph Chappell;Ross Nable

  • Rapid induction of ethylene biosynthesis in cultured parsley cells by fungal elicitor and its relationship to the induction of phenylalanine ammonia-lyase

    Joseph Chappell;Klaus Hahlbrock;Thomas Boller

  • Identification of unique mechanisms for triterpene biosynthesis in Botryococcus braunii.

    Tom D. Niehaus;Shigeru Okada;Timothy P. Devarenne;David S. Watt

  • Cloning, heterologous expression, and functional characterization of 5-epi-aristolochene-1,3-dihydroxylase from tobacco (Nicotiana tabacum).

    Lyle Ralston;Soon Tae Kwon;Mark Schoenbeck;Jennifer Ralston

  • The genetics and molecular genetics of terpene and sterol origami.

    Joe Chappell

Frequent Co-Authors

Joseph P. Noel
Joseph P. Noel Salk Institute for Biological Studies
Robert M. Coates
Robert M. Coates University of Illinois at Urbana-Champaign
Klaus Hahlbrock
Klaus Hahlbrock Max Planck Society
A. Daniel Jones
A. Daniel Jones Michigan State University
C. Robin Buell
C. Robin Buell University of Georgia
Richard D. Vierstra
Richard D. Vierstra Washington University in St. Louis
Maarten J. Chrispeels
Maarten J. Chrispeels University of California, San Diego
Eve Syrkin Wurtele
Eve Syrkin Wurtele Iowa State University
Christopher J. Lamb
Christopher J. Lamb John Innes Centre
Ikhlas A. Khan
Ikhlas A. Khan University of Mississippi

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