Helena Reijonen

Overview

Best Publications

• Recurrence of type 1 diabetes after simultaneous pancreas-kidney transplantation, despite immunosuppression, is associated with autoantibodies and pathogenic autoreactive CD4 T-cells

  Francesco Vendrame;Antonello Pileggi;Elsa Laughlin;Gloria Allende

  292
  Citations

• Clinical, autoimmune, and genetic characteristics of very young children with type 1 diabetes. Childhood Diabetes in Finland (DiMe) Study Group.

  Jorma Komulainen;Petri Kulmala;Kaisa Savola;Raisa Lounamaa

  270
  Citations

• Ultra-sensitive detection of rare T cell clones

  Harlan Robins;Cindy Desmarais;Jessica Matthis;Robert Livingston

  249
  Citations

• Triple-label hybridization assay for type-1 diabetes-related HLA alleles.

  Sjöroos M;Iitiä A;Ilonen J;Reijonen H

  248
  Citations

• Detection of GAD65-Specific T-Cells by Major Histocompatibility Complex Class II Tetramers in Type 1 Diabetic Patients and At-Risk Subjects

  Helena Reijonen;Erik J. Novak;Sharon Kochik;Anne Heninger

  239
  Citations

• Islet Cell Antibody Seroconversion in Children Is Temporally Associated with Enterovirus Infections

  Merja Hiltunen;Heikki Hyöty;Mikael Knip;Jorma Ilonen

  229
  Citations

• Rapid HLA-DQB1 Genotyping for Four Alleles in the Assessment of Risk for IDDM in the Finnish Population

  J Ilonen;H Reijonen;E Herva;M Sjöroos

  196
  Citations

• Coeliac Disease: Frequent Occurrence After Clinical Onset of Insulin‐dependent Diabetes Mellitus

  T. Saukkonen;E. Savilahti;H. Reijonen;J. Ilonen

  196
  Citations

• Cow's milk consumption, HLA-DQB1 genotype, and type 1 diabetes: a nested case-control study of siblings of children with diabetes. Childhood diabetes in Finland study group.

  Suvi M. Virtanen;Esa Läärä;Elina Hyppönen;Helena Reijonen

  184
  Citations

• Islet-specific glucose-6-phosphatase catalytic subunit-related protein-reactive CD4+ T cells in human subjects.

  Junbao Yang;Nancy A. Danke;DeAnna Berger;Sandra Reichstetter

  158
  Citations

• GAD65-Specific CD4 + T-Cells with High Antigen Avidity Are Prevalent in Peripheral Blood of Patients With Type 1 Diabetes

  Helena Reijonen;Roberto Mallone;Anne Kristin Heninger;Elsa M. Laughlin

  150
  Citations

• Autoantigen-specific regulatory T cells induced in patients with Type 1 Diabetes Mellitus by Insulin B-chain immunotherapy

  Tihamer Orban;Klara Farkas;Heyam Jalahej;Janos Kis

  140
  Citations

• Genetic markers, humoral autoimmunity, and prediction of type 1 diabetes in siblings of affected children. Childhood Diabetes in Finland Study Group.

  Petri Kulmala;Kaisa Savola;Helena Reijonen;Riitta Veijola

  137
  Citations

• GAD65- and proinsulin-specific CD4+ T-cells detected by MHC class II tetramers in peripheral blood of type 1 diabetes patients and at-risk subjects.

  Viveka Öling;Jane Marttila;Jorma Ilonen;William W. Kwok

  128
  Citations

• Validity and Reproducibility of Measurement of Islet Autoreactivity by T-Cell Assays in Subjects With Early Type 1 Diabetes

  Kevan C. Herold;Barbara Brooks-Worrell;Jerry Palmer;H. Michael Dosch

  126
  Citations

• Cellular Immune Response to Cow's Milk β-Lactoglobulin in Patients With Newly Diagnosed IDDM

  Outi Vaarala;Paula Klemetti;Erkki Savilahti;Helena Reijonen

  126
  Citations

• Insulin Gene Region-Encoded Susceptibility to IDDM Maps Upstream of the Insulin Gene

  Dag E Undlien;Simon T Bennett;John A Todd;Hanne E Akselsen

  122
  Citations

• GAD65-specific autoantibodies enhance the presentation of an immunodominant T-cell epitope from GAD65.

  Helena Reijonen;Terri L. Daniels;Ake Lernmark;Gerald T. Nepom

  120
  Citations

• Use of HLA class II tetramers in tracking antigen-specific T cells and mapping T-cell epitopes

  Helena Reijonen;William W Kwok

  107
  Citations

• HLA-DQB1-defined genetic susceptibility, beta cell autoimmunity, and metabolic characteristics in familial and nonfamilial insulin-dependent diabetes mellitus. Childhood Diabetes in Finland (DiMe) Study Group.

  R Veijola;H Reijonen;P Vähäsalo;E Sabbah

  107
  Citations

• Linkage disequilibrium between TAP2 variants and HLA class II alleles; no primary association between TAP2 variants and insulin-dependent diabetes mellitus.

  Kjersti S. Rønningen;Dag E. Undlien;Rafal Ploski;Nicki Maouni

  106
  Citations