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Immunology

D-Index
67
Citations
24368
World Ranking
2640
National Ranking
1260

Overview

Eric Meffre is affiliated with Yale University in the United States and has contributed extensively to research in Medicine and Immunology and Microbiology. Their work spans several subfields, including Immunology, Genetics, Pathology and Forensic Medicine, Infectious Diseases, and Molecular Biology.

The scientist's research predominantly focuses on topics such as T-cell and B-cell Immunology, Immune Cell Function and Interaction, Chronic Lymphocytic Leukemia Research, COVID-19 Clinical Research Studies, Immunodeficiency and Autoimmune Disorders, Adrenal Hormones and Disorders, and Lymphoma Diagnosis and Treatment.

Recent publications authored or co-authored by Eric Meffre include:

  • Interferon deficiency can lead to severe COVID, 2020, Nature
  • Inflammasome activation in infected macrophages drives COVID-19 pathology, 2021, bioRxiv (Cold Spring Harbor Laboratory)
  • A humanized mouse model of chronic COVID-19, 2021, Nature Biotechnology
  • Inflammasome activation in infected macrophages drives COVID-19 pathology, 2022, Nature
  • High-throughput identification of autoantibodies that target the human exoproteome, 2022, Cell Reports Methods

Frequent co-authors collaborating with Eric Meffre include Markus Müschen, Kohei Kume, Mark E. Robinson, Kadriye Nehir Cosgun, and Rosa Bacchetta.

The majority of Eric Meffre's publications appear in venues such as bioRxiv (Cold Spring Harbor Laboratory), Journal of Clinical Investigation, Nature, Science Translational Medicine, and The Journal of Immunology.

Best Publications

  • Predominant Autoantibody Production by Early Human B Cell Precursors

    Hedda Wardemann;Sergey Yurasov;Sergey Yurasov;Anne Schaefer;James W. Young

  • Efficient generation of monoclonal antibodies from single human B cells by single cell RT-PCR and expression vector cloning

    Thomas Tiller;Eric Meffre;Sergey Yurasov;Sergey Yurasov;Makoto Tsuiji

  • Immune dysregulation in human subjects with heterozygous germline mutations in CTLA4

    Hye Sun Kuehn;Weiming Ouyang;Bernice Lo;Elissa K. Deenick;Elissa K. Deenick

  • Reprogramming human T cell function and specificity with non-viral genome targeting

    Theodore L. Roth;Cristina Puig-Saus;Ruby Yu;Ruby Yu;Eric Shifrut;Eric Shifrut

  • Defective B cell tolerance checkpoints in systemic lupus erythematosus

    Sergey Yurasov;Hedda Wardemann;Johanna Hammersen;Makoto Tsuiji

  • Transcriptional repressor Blimp-1 promotes CD8(+) T cell terminal differentiation and represses the acquisition of central memory T cell properties.

    Rachel L. Rutishauser;Gislâine A. Martins;Sergey Kalachikov;Anmol Chandele

  • DNA repair protein Ku80 suppresses chromosomal aberrations and malignant transformation.

    Michael J. Difilippantonio;Jie Zhu;Hua Tang Chen;Eric Meffre

  • Mutation of NLRC4 causes a syndrome of enterocolitis and autoinflammation

    Neil Romberg;Khatoun Al Moussawi;Carol Nelson-Williams;Amy L Stiegler

  • Complement receptor 2/CD21- human naive B cells contain mostly autoreactive unresponsive clones

    Isabelle Isnardi;Yen Shing Ng;Laurence Menard;Greta Meyers

  • Cold urticaria, immunodeficiency, and autoimmunity related to PLCG2 deletions.

    Michael J. Ombrello;Elaine F. Remmers;Guangping Sun;Alexandra F. Freeman

  • Continued RAG expression in late stages of B cell development and no apparent re-induction after immunization.

    Wong Yu;Hitoshi Nagaoka;Mila Jankovic;Ziva Misulovin

  • Unmutated and mutated chronic lymphocytic leukemias derive from self-reactive B cell precursors despite expressing different antibody reactivity

    Maxime Hervé;Kai Xu;Yen Shing Ng;Hedda Wardemann

  • Mice lacking the CCR9 CC-chemokine receptor show a mild impairment of early T- and B-cell development and a reduction in T-cell receptor γδ+ gut intraepithelial lymphocytes

    Marc-André Wurbel;Marie Malissen;Delphine Guy-Grand;Eric Meffre

  • Role of BCR affinity in T cell–dependent antibody responses in vivo

    Tien-An Yang Shih;Eric Meffre;Mario Roederer;Michel C. Nussenzweig;Michel C. Nussenzweig

  • The transmembrane activator TACI triggers immunoglobulin class switching by activating B cells through the adaptor MyD88

    Bing He;Raul Santamaria;Weifeng Xu;Montserrat Cols

  • B-cell tolerance checkpoints in health and autoimmunity.

    Eric Meffre;Hedda Wardemann

  • Antibody regulation of B cell development.

    Eric Meffre;Rafael Casellas;Michel C. Nussenzweig

  • In Situ B Cell-Mediated Immune Responses and Tubulointerstitial Inflammation in Human Lupus Nephritis

    Anthony Chang;Scott G. Henderson;Daniel Brandt;Ni Liu

  • The PTPN22 allele encoding an R620W variant interferes with the removal of developing autoreactive B cells in humans

    Laurence Menard;David Saadoun;Isabelle Isnardi;Yen Shing Ng

  • Expansion of Autoreactive Unresponsive CD21−/low B Cells in Sjögren's Syndrome–Associated Lymphoproliferation

    D Saadoun;B Terrier;J Bannock;T Vazquez

  • Chronic lymphocytic leukemia cells recognize conserved epitopes associated with apoptosis and oxidation.

    Rosa Catera;Gregg J. Silverman;Katerina Hatzi;Till Seiler

Frequent Co-Authors

Charlotte Cunningham-Rundles
Charlotte Cunningham-Rundles Icahn School of Medicine at Mount Sinai
Andrea Cerutti
Andrea Cerutti Icahn School of Medicine at Mount Sinai
Kevan C. Herold
Kevan C. Herold Yale University
David Saadoun
David Saadoun Université Paris Cité
Raif S. Geha
Raif S. Geha Boston Children's Hospital
Richard A. Flavell
Richard A. Flavell Yale University
Jean-Laurent Casanova
Jean-Laurent Casanova The University of Texas Southwestern Medical Center
Markus Müschen
Markus Müschen Yale University
Jennifer H. Anolik
Jennifer H. Anolik University of Rochester

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Related Online Degrees & Career Pathways

For those interested in expanding their expertise in Immunology, pursuing related online degrees can open diverse career pathways in healthcare and research. Many professionals begin with fundamental nursing degrees before specializing further. Programs like accelerated BSN programs for non nurses offer a streamlined path for individuals without prior nursing experience to enter the field.

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Furthermore, professionals interested in acute care can consider transitioning through programs focused on moving from FNP to ACNP. This transition equips nurses with the skills to manage complex immunological disorders in critical settings. These online degree pathways not only enhance clinical knowledge but also provide flexible options suited to busy professionals aiming to advance in immunology-related careers.

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