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Achim Hoerauf

Achim Hoerauf

D-Index & Metrics

Immunology

D-Index
83
Citations
24013
World Ranking
1452
National Ranking
99

Overview

Achim Hoerauf is affiliated with the University of Bonn in Germany and has a research focus centered in the fields of Medicine and Immunology and Microbiology. Their work spans several subfields, particularly Infectious Diseases, Parasitology, Ecology, Insect Science, and Public Health, Environmental and Occupational Health.

The main topics covered in their research include Parasitic Diseases Research and Treatment, Parasites and Host Interactions, Parasite Biology and Host Interactions, Insect Symbiosis and Bacterial Influences, Insects and Parasite Interactions, Mosquito-borne Diseases and Control, and Lymphatic System and Diseases.

Frequent collaborators in Achim Hoerauf's research projects include:

  • Manuel Ritter
  • Marc P. Hübner
  • Kenneth Pfarr
  • Samuel Wanji
  • Alexander Yaw Debrah

Achim Hoerauf has published numerous papers in peer-reviewed journals, with recent representative works including:

  • Towards the sustainable discovery and development of new antibiotics, 2021, Nature Reviews Chemistry
  • Immune Sensing of Synthetic, Bacterial, and Protozoan RNA by Toll-like Receptor 8 Requires Coordinated Processing by RNase T2 and RNase 2, 2020, Immunity
  • Comparison of IgA, IgG, and Neutralizing Antibody Responses Following Immunization With Moderna, BioNTech, AstraZeneca, Sputnik-V, Johnson and Johnson, and Sinopharm's COVID-19 Vaccines, 2022, Frontiers in Immunology
  • Efficacy and safety of fexinidazole for treatment of chronic indeterminate Chagas disease (FEXI-12): a multicentre, randomised, double-blind, phase 2 trial, 2024, The Lancet Infectious Diseases
  • Microfilariae Trigger Eosinophil Extracellular DNA Traps in a Dectin-1-Dependent Manner, 2021, Cell Reports

The leading venues where Achim Hoerauf has frequently published include:

  • PLoS Neglected Tropical Diseases
  • Frontiers in Immunology
  • Frontiers in Tropical Diseases
  • http://isrctn.com/
  • Parasites & Vectors

Best Publications

  • Towards the sustainable discovery and development of new antibiotics

    Marcus Miethke;Marco Pieroni;Tilmann Weber;Mark Brönstrup

  • Lymphatic filariasis and onchocerciasis.

    Mark J Taylor;Achim Hoerauf;Moses Bockarie

  • Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry for Fast and Reliable Identification of Clinical Yeast Isolates

    G. Marklein;M. Josten;U. Klanke;E. Müller

  • Antigen-specific cellular hyporesponsiveness in a chronic human helminth infection is mediated by Th3/Tr1-type cytokines IL-10 and transforming growth factor-β but not by a Th1 to Th2 shift

    Andrea Doetze;Judith Satoguina;Gerd Burchard;Thomas Rau

  • Wolbachia bacterial endosymbionts of filarial nematodes.

    Mark J. Taylor;Claudio Bandi;Achim Hoerauf

  • The role of endosymbiotic Wolbachia bacteria in the pathogenesis of river blindness

    Amélie v. Saint André;Nathan M. Blackwell;Laurie R. Hall;Achim Hoerauf

  • Tetracycline therapy targets intracellular bacteria in the filarial nematode Litomosoides sigmodontis and results in filarial infertility

    Achim Hoerauf;Kerstin Nissen-Pähle;Christel Schmetz;Kim Henkle-Dührsen

  • Wolbachia Bacteria of Filarial Nematodes

    M.J Taylor;A Hoerauf

  • Endosymbiotic bacteria in worms as targets for a novel chemotherapy in filariasis

    Achim Hoerauf;Lars Volkmann;Christoph Hamelmann;Ohene Adjei

  • Macrofilaricidal activity after doxycycline treatment of Wuchereria bancrofti: a double-blind, randomised placebo-controlled trial

    Mark J Taylor;Williams H Makunde;Williams H Makunde;Helen F McGarry;Joseph D Turner

  • Depletion of wolbachia endobacteria in Onchocerca volvulus by doxycycline and microfilaridermia after ivermectin treatment

    Achim Hoerauf;Sabine Mand;Ohene Adjei;Bernhard Fleischer

  • Antigen-specific T regulatory-1 cells are associated with immunosuppression in a chronic helminth infection (onchocerciasis).

    Judith Satoguina;Martin Mempel;John Larbi;Marlis Badusche

  • Wolbachia endobacteria depletion by doxycycline as antifilarial therapy has macrofilaricidal activity in onchocerciasis: a randomized placebo-controlled study

    Achim Hoerauf;Sabine Specht;Marcelle Büttner;Kenneth Pfarr

  • Mass drug treatment for lymphatic filariasis and onchocerciasis.

    David H Molyneux;Mark Bradley;Achim Hoerauf;Dominique Kyelem

  • Filariasis: new drugs and new opportunities for lymphatic filariasis and onchocerciasis.

    Achim Hoerauf

  • Doxycycline in the treatment of human onchocerciasis: Kinetics of Wolbachia endobacteria reduction and of inhibition of embryogenesis in female Onchocerca worms.

    Achim Hoerauf;Sabine Mand;Lars Volkmann;Marcelle Büttner

  • The Major Surface Protein of Wolbachia Endosymbionts in Filarial Nematodes Elicits Immune Responses through TLR2 and TLR4

    Norbert W. Brattig;Chiara Bazzocchi;Carsten J. Kirschning;Norbert Reiling

  • Immunomodulation by filarial nematodes.

    A. Hoerauf;J. Satoguina;M. Saeftel;S. Specht

  • Doxycycline reduces plasma VEGF-C/sVEGFR-3 and improves pathology in lymphatic filariasis.

    Alexander Yaw Debrah;Sabine Mand;Sabine Specht;Yeboah Marfo-Debrekyei

  • Neutrophil accumulation around Onchocerca worms and chemotaxis of neutrophils are dependent on Wolbachia endobacteria.

    Norbert W. Brattig;Dietrich W. Büttner;Achim Hoerauf

  • T Regulatory-1 Cells Induce IgG4 Production by B Cells: Role of IL-10

    Judith S. Satoguina;Judith S. Satoguina;Esther Weyand;John Larbi;Achim Hoerauf;Achim Hoerauf

  • Doxycycline as a novel strategy against bancroftian filariasis-depletion of Wolbachia endosymbionts from Wuchereria bancrofti and stop of microfilaria production.

    Achim Hoerauf;Sabine Mand;Kerstin Fischer;Thomas Kruppa

  • Filariasis and lymphoedema

    K. M. Pfarr;A. Y. Debrah;A. Y. Debrah;S. Specht;A. Hoerauf

Frequent Co-Authors

Mark J. Taylor
Mark J. Taylor Liverpool School of Tropical Medicine
Ulrich Spengler
Ulrich Spengler University of Bonn
Christian P. Strassburg
Christian P. Strassburg University Hospital Bonn
Bernhard Fleischer
Bernhard Fleischer Bernhard Nocht Institute for Tropical Medicine
Jacob Nattermann
Jacob Nattermann University Hospital Bonn
Joseph D. Turner
Joseph D. Turner Liverpool School of Tropical Medicine
Johannes Oldenburg
Johannes Oldenburg University of Bonn
Hidayat Hussain
Hidayat Hussain Leibniz Association
Tilman Sauerbruch
Tilman Sauerbruch University of Bonn
Odile Bain
Odile Bain Centre national de la recherche scientifique, CNRS

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