What is he best known for?
The fields of study he is best known for:
The scientist’s investigation covers issues in Notch signaling pathway, Notch proteins, Cell biology, Genetics and Signal transduction.
Spyros Artavanis-Tsakonas interconnects Molecular biology, Vertebrate and Regenerative medicine in the investigation of issues within Notch signaling pathway.
He has researched Notch proteins in several fields, including Mutation, Hairless, Hes3 signaling axis, Ankyrin repeat and Serrate-Jagged Proteins.
His Cell biology research includes themes of Immunology, Cellular differentiation and Transmembrane domain.
His research investigates the connection between Genetics and topics such as Computational biology that intersect with problems in Proteomics and Genome.
His research in Signal transduction tackles topics such as Cell fate determination which are related to areas like Cancer, Cell, Anatomy and Cell surface receptor.
His most cited work include:
- Notch Signaling: Cell Fate Control and Signal Integration in Development (5048 citations)
- Notch signaling : Signal transduction (1218 citations)
- Nucleotide sequence from the neurogenic locus Notch implies a gene product that shares homology with proteins containing EGF-like repeats (910 citations)
What are the main themes of his work throughout his whole career to date?
His primary scientific interests are in Notch signaling pathway, Cell biology, Genetics, Notch proteins and Signal transduction.
His Notch signaling pathway research is multidisciplinary, incorporating perspectives in Molecular biology, Cellular differentiation and Cell fate determination.
His study in Cellular differentiation is interdisciplinary in nature, drawing from both Progenitor cell and Neuroscience.
The concepts of his Cell biology study are interwoven with issues in Receptor and Cleavage.
Spyros Artavanis-Tsakonas combines subjects such as Hairless, Mutation, Transmembrane protein, Ankyrin repeat and Genetic screen with his study of Notch proteins.
His Signal transduction study incorporates themes from Genetically modified mouse and Ubiquitin ligase.
He most often published in these fields:
- Notch signaling pathway (86.81%)
- Cell biology (71.98%)
- Genetics (56.04%)
What were the highlights of his more recent work (between 2010-2020)?
- Notch signaling pathway (86.81%)
- Cell biology (71.98%)
- Genetics (56.04%)
In recent papers he was focusing on the following fields of study:
Spyros Artavanis-Tsakonas mainly investigates Notch signaling pathway, Cell biology, Genetics, Signal transduction and Notch proteins.
His work deals with themes such as Cell, Endosome, Haematopoiesis, Pathology and Neuroscience, which intersect with Notch signaling pathway.
His Cell biology research integrates issues from Receptor and Cellular differentiation.
His Cellular differentiation study combines topics in areas such as Molecular biology and Gene knockin.
His research investigates the connection with Genetics and areas like Computational biology which intersect with concerns in Human interactome, Protein–protein interaction, Interactome, Gene and Proteomics.
His Notch proteins research focuses on subjects like Cell fate determination, which are linked to Cell growth, Tyrosine kinase, Proto-oncogene tyrosine-protein kinase Src and Genetic screen.
Between 2010 and 2020, his most popular works were:
- The BioPlex Network: A Systematic Exploration of the Human Interactome (837 citations)
- The BioPlex Network: A Systematic Exploration of the Human Interactome (837 citations)
- Architecture of the human interactome defines protein communities and disease networks (670 citations)
In his most recent research, the most cited papers focused on:
His scientific interests lie mostly in Notch signaling pathway, Genetics, Computational biology, Signal transduction and Notch proteins.
His Notch signaling pathway study combines topics from a wide range of disciplines, such as Disease, Pathology, Neuroscience and CADASIL.
The Computational biology study combines topics in areas such as Drosophila melanogaster, Proteomics and Human interactome.
His work is dedicated to discovering how Signal transduction, Genome are connected with Human proteome project and Open reading frame and other disciplines.
His study with Notch proteins involves better knowledge in Cell biology.
In general Cell biology, his work in Cell signaling is often linked to Context linking many areas of study.
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