1996 - Fellow of the American Academy of Arts and Sciences
The scientist’s investigation covers issues in Notch signaling pathway, Notch proteins, Cell biology, Genetics and Signal transduction. Spyros Artavanis-Tsakonas interconnects Molecular biology, Vertebrate and Regenerative medicine in the investigation of issues within Notch signaling pathway. He has researched Notch proteins in several fields, including Mutation, Hairless, Hes3 signaling axis, Ankyrin repeat and Serrate-Jagged Proteins.
His Cell biology research includes themes of Immunology, Cellular differentiation and Transmembrane domain. His research investigates the connection between Genetics and topics such as Computational biology that intersect with problems in Proteomics and Genome. His research in Signal transduction tackles topics such as Cell fate determination which are related to areas like Cancer, Cell, Anatomy and Cell surface receptor.
His primary scientific interests are in Notch signaling pathway, Cell biology, Genetics, Notch proteins and Signal transduction. His Notch signaling pathway research is multidisciplinary, incorporating perspectives in Molecular biology, Cellular differentiation and Cell fate determination. His study in Cellular differentiation is interdisciplinary in nature, drawing from both Progenitor cell and Neuroscience.
The concepts of his Cell biology study are interwoven with issues in Receptor and Cleavage. Spyros Artavanis-Tsakonas combines subjects such as Hairless, Mutation, Transmembrane protein, Ankyrin repeat and Genetic screen with his study of Notch proteins. His Signal transduction study incorporates themes from Genetically modified mouse and Ubiquitin ligase.
Spyros Artavanis-Tsakonas mainly investigates Notch signaling pathway, Cell biology, Genetics, Signal transduction and Notch proteins. His work deals with themes such as Cell, Endosome, Haematopoiesis, Pathology and Neuroscience, which intersect with Notch signaling pathway. His Cell biology research integrates issues from Receptor and Cellular differentiation.
His Cellular differentiation study combines topics in areas such as Molecular biology and Gene knockin. His research investigates the connection with Genetics and areas like Computational biology which intersect with concerns in Human interactome, Protein–protein interaction, Interactome, Gene and Proteomics. His Notch proteins research focuses on subjects like Cell fate determination, which are linked to Cell growth, Tyrosine kinase, Proto-oncogene tyrosine-protein kinase Src and Genetic screen.
His scientific interests lie mostly in Notch signaling pathway, Genetics, Computational biology, Signal transduction and Notch proteins. His Notch signaling pathway study combines topics from a wide range of disciplines, such as Disease, Pathology, Neuroscience and CADASIL. The Computational biology study combines topics in areas such as Drosophila melanogaster, Proteomics and Human interactome.
His work is dedicated to discovering how Signal transduction, Genome are connected with Human proteome project and Open reading frame and other disciplines. His study with Notch proteins involves better knowledge in Cell biology. In general Cell biology, his work in Cell signaling is often linked to Context linking many areas of study.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Notch Signaling: Cell Fate Control and Signal Integration in Development
Spyros Artavanis-Tsakonas;Matthew D. Rand;Robert J. Lake.
Notch signaling : Signal transduction
S. Artavanis-Tsakonas;K. Matsuno;M. E. Fortini.
Nucleotide sequence from the neurogenic locus Notch implies a gene product that shares homology with proteins containing EGF-like repeats
Kristi A. Wharton;Kristen M. Johansen;Tian Xu;Spyros Artavanis-Tsakonas.
Notch signalling in vertebrate neural development
Angeliki Louvi;Spyros Artavanis-Tsakonas;Spyros Artavanis-Tsakonas.
Nature Reviews Neuroscience (2006)
Notch signals control the fate of immature progenitor cells in the intestine
Silvia Fre;Mathilde Huyghe;Philippos Mourikis;Philippos Mourikis;Sylvie Robine.
Specific EGF repeats of Notch mediate interactions with Delta and serrate: Implications for notch as a multifunctional receptor
Ilaria Rebay;Robert J. Fleming;Richard G. Fehon;Lucy Cherbas.
The BioPlex Network: A Systematic Exploration of the Human Interactome
Edward L. Huttlin;Lily Ting;Raphael J. Bruckner;Fana Gebreab.
Molecular interactions between the protein products of the neurogenic loci Notch and Delta, two EGF-homologous genes in Drosophila
Richard G. Fehon;Pamela J. Kooh;Ilaria Rebay;Cathy L. Regan.
Intracellular Cleavage of Notch Leads to a Heterodimeric Receptor on the Plasma Membrane
Christine M Blaumueller;Huilin Qi;Panayiotis Zagouras;Spyros Artavanis-Tsakonas.
THE SUPPRESSOR OF HAIRLESS PROTEIN PARTICIPATES IN NOTCH RECEPTOR SIGNALING
Mark E. Fortini;Spyros Artavanis-Tsakonas.
If you think any of the details on this page are incorrect, let us know.
We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below: