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Molecular Biology

D-Index
45
Citations
9561
World Ranking
2849
National Ranking
1362

Research.com Recognitions

  • 1957 - Fellow of John Simon Guggenheim Memorial Foundation

Overview

David Van Vactor is affiliated with Harvard University in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, with a particular focus on Molecular Biology and Cellular and Molecular Neuroscience.

Their work covers several key topics, including RNA Research and Splicing, Neurobiology and Insect Physiology Research, Physiological and Biochemical Adaptations, MicroRNA in Disease Regulation, Genetic Neurodegenerative Diseases, Mitochondrial Function and Pathology, and Health and Medical Research Impacts.

David Van Vactor has contributed to multiple publications across notable venues. The most frequent places of publication include bioRxiv (Cold Spring Harbor Laboratory), Neural Development, iScience, eLife, and Nature Communications.

  • Control of feeding by Piezo-mediated gut mechanosensation in Drosophila, 2021, eLife
  • Synapse development and maturation at the drosophila neuromuscular junction, 2020, Neural Development
  • The conserved microRNA miR-34 regulates synaptogenesis via coordination of distinct mechanisms in presynaptic and postsynaptic cells, 2020, Nature Communications
  • Single-nuclei transcriptome analysis of Huntington disease iPSC and mouse astrocytes implicates maturation and functional deficits, 2022, iScience
  • miRNA: local guardians of presynaptic function in plasticity and disease, 2021, RNA Biology

The scientist has collaborated frequently with a number of coauthors, including Vivian Chou, Pushpa Verma, Elizabeth M. McNeill, Alicia Taylor, and Andrea M. Reyes-Ortiz.

David Van Vactor's career includes recognition such as being named a Fellow of the John Simon Guggenheim Memorial Foundation in 1957.

Best Publications

  • The trip of the tip: understanding the growth cone machinery

    Laura Anne Lowery;David Van Vactor

  • Drosophila Liprin-α and the Receptor Phosphatase Dlar Control Synapse Morphogenesis

    Nancy Kaufmann;Jamin DeProto;Ravi Ranjan;Hong Wan

  • The tyrosine kinase Abl and its substrate enabled collaborate with the receptor phosphatase Dlar to control motor axon guidance.

    Zachary Wills;Jack Bateman;Christopher A Korey;Allen Comer

  • The Guanine Nucleotide Exchange Factor Trio Mediates Axonal Development in the Drosophila Embryo

    Jack Bateman;Huidy Shu;David Van Vactor

  • MicroRNAs Shape the Neuronal Landscape

    Elizabeth McNeill;David Van Vactor

  • The HSPGs Syndecan and Dallylike Bind the Receptor Phosphatase LAR and Exert Distinct Effects on Synaptic Development

    Karl G. Johnson;Alan P. Tenney;Aurnab Ghose;April M. Duckworth

  • Profilin and the Abl Tyrosine Kinase Are Required for Motor Axon Outgrowth in the Drosophila Embryo

    Zachary Wills;Linsey Marr;Kai Zinn;Corey S Goodman

  • Receptor Protein Tyrosine Phosphatases in Nervous System Development

    Karl G. Johnson;David Van Vactor

  • The Microtubule Plus End Tracking Protein Orbit/MAST/CLASP Acts Downstream of the Tyrosine Kinase Abl in Mediating Axon Guidance

    Haeryun Lee;Ulrike Engel;Jannette Rusch;Simone Scherrer

  • Axonal heparan sulfate proteoglycans regulate the distribution and efficiency of the repellent slit during midline axon guidance.

    Karl G Johnson;Aurnab Ghose;Elizabeth Epstein;John Lincecum

  • Dysregulation of microRNA-219 promotes neurodegeneration through post-transcriptional regulation of tau

    Ismael Santa-Maria;Maria E. Alaniz;Neil Renwick;Carolina Cela

  • Induction in the developing compound eye of Drosophila: Multiple mechanisms restrict R7 induction to a single retinal precursor cell

    David L. Van Vactor;Ross L. Cagan;Helmut Krämer;S.Lawrence Zipursky

  • Modeling Spinal Muscular Atrophy in Drosophila

    Howard Chia-Hao Chang;Douglas N. Dimlich;Takakazu Yokokura;Ashim Mukherjee

  • Transgenic microRNA inhibition with spatiotemporal specificity in intact organisms

    Carlos M Loya;Cecilia S Lu;David Van Vactor;Tudor A Fulga

  • Genetic analysis of protein tyrosine phosphatases

    David Van Vactor;Alana M O'Reilly;Benjamin G Neel

  • The receptor tyrosine phosphatase Dlar and integrins organize actin filaments in the Drosophila follicular epithelium

    Jack Bateman;R.Srekantha Reddy;Haruo Saito;David Van Vactor

  • QIL1 is a novel mitochondrial protein required for MICOS complex stability and cristae morphology

    Virginia Guarani;Elizabeth M McNeill;Joao A Paulo;Edward L Huttlin

  • Direct Observation Demonstrates that Liprin-α Is Required for Trafficking of Synaptic Vesicles

    Kyle E. Miller;Jamin DeProto;Nancy Kaufmann;Bharatkumar N. Patel

  • Enabled plays key roles in embryonic epithelial morphogenesis in Drosophila

    Julie Gates;Julie Gates;James P. Mahaffey;Stephen L. Rogers;Mark Emerson

  • miR-132 Enhances Dendritic Morphogenesis, Spine Density, Synaptic Integration, and Survival of Newborn Olfactory Bulb Neurons

    Manavendra Pathania;Juan Torres-Reveron;Lily D Yan;Tomoki Kimura

Frequent Co-Authors

Spyros Artavanis-Tsakonas
Spyros Artavanis-Tsakonas Harvard University
Norbert Perrimon
Norbert Perrimon Harvard University
John G. Flanagan
John G. Flanagan University of California, Berkeley
Gaudenz Danuser
Gaudenz Danuser The University of Texas Southwestern Medical Center
Leslie C. Griffith
Leslie C. Griffith Brandeis University
Haruo Saito
Haruo Saito University of Tokyo
Stephen D. Liberles
Stephen D. Liberles Harvard University
Dennis P. Wall
Dennis P. Wall Stanford University
Angélique Bordey
Angélique Bordey Yale University
Eric C. Lai
Eric C. Lai Memorial Sloan Kettering Cancer Center

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