2026 Richard E. Mains: Biology and Biochemistry Researcher – H-Index, Publications & Awards

D-Index & Metrics

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Biology and Biochemistry	89	2590	2378	1354	1219	341	26005

Discipline name

D-Index

World Ranking

Current World Ranking

National Ranking

Current National Ranking

Publications

Citations

Biology and Biochemistry

2590

2378

1354

1219

341

26005

Biology and Biochemistry

D-Index

Citations

26005

World Ranking

2590

National Ranking

1354

Overview

Richard E. Mains is affiliated with the University of Connecticut Health Center in the United States. Their research primarily focuses on biochemistry, genetics, and molecular biology, with significant contributions to medicine. Key subfields of their work include molecular biology, cellular and molecular neuroscience, cardiology and cardiovascular medicine, physiology, and surgery.

The scientist's research addresses several main topics, such as:

Pancreatic function and diabetes
Neuroscience and neuropharmacology research
Photosynthetic processes and mechanisms
Atrial fibrillation management and outcomes
Cardiac electrophysiology and arrhythmias
Pituitary gland disorders and treatments
Cancer, hypoxia, and metabolism

Among their recent papers are:

Peptidylglycine α-amidating monooxygenase is required for atrial secretory granule formation, 2020, Proceedings of the National Academy of Sciences
Peptidylglycine α-amidating monooxygenase as a therapeutic target or biomarker for human diseases, 2022, British Journal of Pharmacology
PAM haploinsufficiency does not accelerate the development of diet- and human IAPP-induced diabetes in mice, 2020, Diabetologia
Germline loss-of-function PAM variants are enriched in subjects with pituitary hypersecretion, 2023, Frontiers in Endocrinology
PAM: diverse roles in neuroendocrine cells, cardiomyocytes, and green algae, 2021, FEBS Journal

The scientist frequently publishes in the following venues:

Zenodo (CERN European Organization for Nuclear Research)
bioRxiv (Cold Spring Harbor Laboratory)
Proceedings of the National Academy of Sciences
Diabetologia
British Journal of Pharmacology

Richard E. Mains collaborates regularly with several coauthors, including:

Betty Eipper
Giampaolo Trivellin
Adrian Daly
Laura C. Hernández-Ramírez
Elisa Araldi

Best Publications

Common precursor to corticotropins and endorphins

Richard E. Mains;Betty A. Eipper;Nicholas Ling

1674
Citations
Structure and Biosynthesis of Pro-Adrenocorticotropin/Endorphin and Related Peptides*

Betty A. Eipper;Richard E. Mains

1209
Citations
The Biosynthesis of Neuropeptides: Peptide alpha-Amidation

B A Eipper;D A Stoffers;R E Mains

734
Citations
Rapid induction of dendritic spine morphogenesis by trans-synaptic ephrinB-EphB receptor activation of the Rho-GEF kalirin.

Peter Penzes;Alexander Beeser;Jonathan Chernoff;Martin R. Schiller

613
Citations
PRIMARY CULTURES OF DISSOCIATED SYMPATHETIC NEURONS : I. Establishment of Long-Term Growth in Culture and Studies of Differentiated Properties

Richard E. Mains;Paul H. Patterson

604
Citations
Identification in pituitary tissue of a peptide alpha-amidation activity that acts on glycine-extended peptides and requires molecular oxygen, copper, and ascorbic acid

Betty A. Eipper;Richard E. Mains;Christopher C. Glembotski

517
Citations
New insights into copper monooxygenases and peptide amidation: structure, mechanism and function.

S. T. Prigge;R. E. Mains;B. A. Eipper;L. M. Amzel

513
Citations
The neuronal Rho-GEF Kalirin-7 interacts with PDZ domain-containing proteins and regulates dendritic morphogenesis.

Peter Penzes;Richard C. Johnson;Rita Sattler;Xiaoqun Zhang

477
Citations
Dioxygen Binds End-On to Mononuclear Copper in a Precatalytic Enzyme Complex

Sean T. Prigge;Betty A. Eipper;Richard E. Mains;L. Mario Amzel

463
Citations
Amidation of Bioactive Peptides: The Structure of Peptidylglycine α-Hydroxylating Monooxygenase

Sean T. Prigge;Aparna S. Kolhekar;Betty A. Eipper;Richard E. Mains

412
Citations
Inducible Genetic Suppression of Neuronal Excitability

David C. Johns;Ruth Marx;Richard E. Mains;Brian O’Rourke

379
Citations
Synthesis and secretion of corticotropins, melanotropins, and endorphins by rat intermediate pituitary cells.

R E Mains;B A Eipper

372
Citations
The prohormone convertases PC1 and PC2 mediate distinct endoproteolytic cleavages in a strict temporal order during proopiomelanocortin biosynthetic processing.

An Zhou;B. T. Bloomquist;R. E. Mains

363
Citations
Peptide alpha-amidation.

B A Eipper;R E Mains

343
Citations
Peptidylglycine alpha-amidating monooxygenase: a multifunctional protein with catalytic, processing, and routing domains.

Eipper Ba;Milgram Sl;Husten Ej;Yun Hy

341
Citations
Biosynthesis of adrenocorticotropic hormone in mouse pituitary tumor cells.

R E Mains;B A Eipper

340
Citations
Existence of a common precursor to ACTH and endorphin in the anterior and intermediate lobes of the rat pituaitary

Betty A. Eipper;Richard E. Mains

261
Citations
Prohormone-Converting Enzymes: Regulation and Evaluation of Function Using Antisense RNA

Brian T. Bloomquist;Betty A. Eipper;Richard E. Mains

261
Citations
Analysis of the common precursor to corticotropin and endorphin.

B A Eipper;R E Mains

257
Citations
PRIMARY CULTURES OF DISSOCIATED SYMPATHETIC NEURONS III. Changes in Metabolism with Age in Culture

Richard E. Mains;Paul H. Patterson

85
Citations