What is he best known for?
The fields of study he is best known for:
His primary scientific interests are in Cell biology, Apoptosis, Molecular biology, Myocyte and Internal medicine.
His Transfection research extends to Cell biology, which is thematically connected.
The various areas that Christopher C. Glembotski examines in his Apoptosis study include Tumor necrosis factor alpha and Signal transduction.
Christopher C. Glembotski has included themes like Mitogen-activated protein kinase, Receptor and Protein kinase A, p38 mitogen-activated protein kinases in his Molecular biology study.
His Myocyte research includes themes of Heat shock protein and Phosphorylation.
His Internal medicine study incorporates themes from Endocrinology, Transcription factor and Transgene.
His most cited work include:
- Tumor necrosis factor alpha-induced apoptosis in cardiac myocytes. Involvement of the sphingolipid signaling cascade in cardiac cell death. (680 citations)
- Cardiotrophin-1 Activates a Distinct Form of Cardiac Muscle Cell Hypertrophy ASSEMBLY OF SARCOMERIC UNITS IN SERIES VIA gp130/LEUKEMIA INHIBITORY FACTOR RECEPTOR-DEPENDENT PATHWAYS (347 citations)
- Identification in pituitary tissue of a peptide alpha-amidation activity that acts on glycine-extended peptides and requires molecular oxygen, copper, and ascorbic acid (317 citations)
What are the main themes of his work throughout his whole career to date?
His primary areas of study are Cell biology, Internal medicine, Endocrinology, Endoplasmic reticulum and Myocyte.
His Cell biology study integrates concerns from other disciplines, such as Heat shock protein and Transcription factor.
His work on Heart failure, Paracrine signalling, Autocrine signalling and Peptide hormone as part of general Internal medicine study is frequently connected to Phenylephrine, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them.
His research integrates issues of Receptor, Protein kinase C and Calcium in his study of Endocrinology.
His work on Unfolded protein response and ATF6 as part of general Endoplasmic reticulum research is frequently linked to Membrane protein, bridging the gap between disciplines.
Christopher C. Glembotski interconnects Apoptosis, Cell, Cardiovascular physiology and Protein biosynthesis in the investigation of issues within Myocyte.
He most often published in these fields:
- Cell biology (50.35%)
- Internal medicine (37.76%)
- Endocrinology (36.36%)
What were the highlights of his more recent work (between 2015-2020)?
- Cell biology (50.35%)
- Unfolded protein response (27.27%)
- Endoplasmic reticulum (32.87%)
In recent papers he was focusing on the following fields of study:
Christopher C. Glembotski spends much of his time researching Cell biology, Unfolded protein response, Endoplasmic reticulum, ATF6 and Myocyte.
His Cell biology study combines topics in areas such as Transcription factor and Gene expression.
His work carried out in the field of Unfolded protein response brings together such families of science as Secretion, Internal medicine, Heart disease and Knockout mouse.
His Internal medicine research focuses on In vivo and how it relates to Tumor necrosis factor alpha, BMS-345541, Ca2+/calmodulin-dependent protein kinase and NFKB1.
His studies deal with areas such as Stroke, Neuroscience, Gene knockdown and Effector as well as ATF6.
His Myocyte research is multidisciplinary, relying on both Fibroblast, Transforming growth factor, Myocardial infarction and Cardiovascular physiology.
Between 2015 and 2020, his most popular works were:
- ATF6 Decreases Myocardial Ischemia/Reperfusion Damage and Links ER Stress and Oxidative Stress Signaling Pathways in the Heart (116 citations)
- Pharmacologic ATF6 activation confers global protection in widespread disease models by reprograming cellular proteostasis. (62 citations)
- ATF6 Regulates Cardiac Hypertrophy by Transcriptional Induction of the mTORC1 Activator, Rheb. (46 citations)
In his most recent research, the most cited papers focused on:
His main research concerns Unfolded protein response, Endoplasmic reticulum, Internal medicine, ATF6 and Proteostasis.
His research investigates the connection between Unfolded protein response and topics such as Myocardial infarction that intersect with issues in Circulatory system.
His study with Endoplasmic reticulum involves better knowledge in Cell biology.
The various areas that Christopher C. Glembotski examines in his Internal medicine study include Endocrinology and Cardiology.
His study in ATF6 is interdisciplinary in nature, drawing from both Stroke, Neuroscience and Activating transcription factor.
The Proteostasis study combines topics in areas such as Function, Cytosol, Ischemia, Myocyte and Mitochondrion.
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