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Christopher C. Glembotski

Christopher C. Glembotski

D-Index & Metrics

Biology and Biochemistry

D-Index
77
Citations
15922
World Ranking
4898
National Ranking
2348

Overview

Christopher C. Glembotski is affiliated with the University of Arizona in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, with substantial contributions to Medicine.

The scientist's work focuses on several subfields including Molecular Biology, Cell Biology, Cardiology and Cardiovascular Medicine, Pulmonary and Respiratory Medicine, and Epidemiology.

The main research topics covered by their publications include:

  • Endoplasmic Reticulum Stress and Disease
  • CRISPR and Genetic Engineering
  • Heat shock proteins research
  • Pulmonary Hypertension Research and Treatments
  • Autophagy in Disease and Therapy
  • Genetics, Aging, and Longevity in Model Organisms
  • RNA regulation and disease

Some of Christopher C. Glembotski's recent papers are:

  • ATF6 as a Nodal Regulator of Proteostasis in the Heart, 2020, Frontiers in Physiology
  • Dietary choline intake is necessary to prevent systems-wide organ pathology and reduce Alzheimer's disease hallmarks, 2023, Aging Cell
  • Mesencephalic astrocyte-derived neurotrophic factor is an ER-resident chaperone that protects against reductive stress in the heart, 2020, Journal of Biological Chemistry
  • The ER Unfolded Protein Response Effector, ATF6, Reduces Cardiac Fibrosis and Decreases Activation of Cardiac Fibroblasts, 2020, International Journal of Molecular Sciences
  • Integrating ER and Mitochondrial Proteostasis in the Healthy and Diseased Heart, 2020, Frontiers in Cardiovascular Medicine

The researcher frequently publishes in several venues, including:

  • Circulation
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Molecular and Cellular Cardiology
  • Journal of Molecular and Cellular Cardiology Plus
  • The FASEB Journal

Christopher C. Glembotski has collaborated extensively with several coauthors, among them:

  • Erik A. Blackwood
  • Alina S. Bilal
  • Donna J. Thuerauf
  • Adrian Arrieta
  • Winston T Stauffer

Best Publications

  • Tumor necrosis factor alpha-induced apoptosis in cardiac myocytes. Involvement of the sphingolipid signaling cascade in cardiac cell death.

    K. A. Krown;M. T. Page;C. Nguyen;D. Zechner

  • Identification in pituitary tissue of a peptide alpha-amidation activity that acts on glycine-extended peptides and requires molecular oxygen, copper, and ascorbic acid

    Betty A. Eipper;Richard E. Mains;Christopher C. Glembotski

  • Cardiotrophin-1 Activates a Distinct Form of Cardiac Muscle Cell Hypertrophy ASSEMBLY OF SARCOMERIC UNITS IN SERIES VIA gp130/LEUKEMIA INHIBITORY FACTOR RECEPTOR-DEPENDENT PATHWAYS

    Kai C. Wollert;Tetsuya Taga;Mikiyoshi Saito;Masashi Narazaki

  • p38 MAPK and NF-κB Collaborate to Induce Interleukin-6 Gene Expression and Release EVIDENCE FOR A CYTOPROTECTIVE AUTOCRINE SIGNALING PATHWAY IN A CARDIAC MYOCYTE MODEL SYSTEM

    Rian Craig;Andrea M Larkin;Amy M Mingo;Donna J Thuerauf

  • A role for the p38 mitogen-activated protein kinase pathway in myocardial cell growth, sarcomeric organization, and cardiac-specific gene expression.

    Dietmar Zechner;Donna J. Thuerauf;Deanna S. Hanford;Patrick M. McDonough

  • Endoplasmic Reticulum Stress Gene Induction and Protection From Ischemia/Reperfusion Injury in the Hearts of Transgenic Mice With a Tamoxifen-Regulated Form of ATF6

    Joshua J. Martindale;Rayne Fernandez;Donna Thuerauf;Ross Whittaker

  • Activation of the Unfolded Protein Response in Infarcted Mouse Heart and Hypoxic Cultured Cardiac Myocytes

    Donna J. Thuerauf;Marie Marcinko;Natalie Gude;Marta Rubio

  • MKK6 Activates Myocardial Cell NF-κB and Inhibits Apoptosis in a p38 Mitogen-activated Protein Kinase-dependent Manner *

    Dietmar Zechner;Rian Craig;Deanna S. Hanford;Patrick M. McDonough

  • LPS-induced autophagy is mediated by oxidative signaling in cardiomyocytes and is associated with cytoprotection.

    Hua Yuan;Cynthia N. Perry;Chengqun Huang;Eri Iwai-Kanai

  • ATF6 Decreases Myocardial Ischemia/Reperfusion Damage and Links ER Stress and Oxidative Stress Signaling Pathways in the Heart.

    Jung-Kang Jin;Erik A Blackwood;Khalid M Azizi;Donna J Thuerauf

  • Endoplasmic reticulum stress in the heart.

    Christopher C. Glembotski

  • Pim-1 regulates cardiomyocyte survival downstream of Akt

    John A Muraski;Marcello Rota;Yu Misao;Jenna Fransioli

  • β1 Integrins Participate in the Hypertrophic Response of Rat Ventricular Myocytes

    Robert S. Ross;Can Pham;Shaw Yung Shai;Joshua I. Goldhaber

  • Strategies for the biosynthesis of bioactive peptides

    Richard E. Mains;Betty A. Eipper;Christopher C. Glembotski;Robert M. Dores

  • Mesencephalic Astrocyte-Derived Neurotrophic Factor Is an Ischemia-Inducible Secreted Endoplasmic Reticulum Stress Response Protein in the Heart

    Archana Tadimalla;Peter J. Belmont;Donna J. Thuerauf;Matthew S. Glassy

  • Dissociation of p44 and p42 Mitogen-activated Protein Kinase Activation from Receptor-induced Hypertrophy in Neonatal Rat Ventricular Myocytes (*)

    Ginell R. Post;David Goldstein;Donna J. Thuerauf;Christopher C. Glembotski

  • Mesencephalic Astrocyte-derived Neurotrophic Factor Protects the Heart from Ischemic Damage and Is Selectively Secreted upon Sarco/endoplasmic Reticulum Calcium Depletion

    Christopher C. Glembotski;Donna J. Thuerauf;Chengqun Huang;John A. Vekich

  • Mimicking Phosphorylation of αB-Crystallin on Serine-59 Is Necessary and Sufficient to Provide Maximal Protection of Cardiac Myocytes From Apoptosis

    Lisa E. Morrison;Holly E. Hoover;Donna J. Thuerauf;Christopher C. Glembotski

  • Opposing Roles for ATF6α and ATF6β in Endoplasmic Reticulum Stress Response Gene Induction

    Donna J. Thuerauf;Lisa Morrison;Christopher C. Glembotski

  • Abstract 1523: Pim-1 Regulates Cardiomyocyte Survival Downstream of Akt

    John A Muraski;Jenna Fransioli;Natalie Gude;Joshua Martindale

Frequent Co-Authors

Mark A. Sussman
Mark A. Sussman San Diego State University
Roberta A. Gottlieb
Roberta A. Gottlieb Cedars-Sinai Medical Center
Richard E. Mains
Richard E. Mains University of Connecticut Health Center
Betty A. Eipper
Betty A. Eipper University of Connecticut Health Center
Steven R. Houser
Steven R. Houser Temple University
Xander H.T. Wehrens
Xander H.T. Wehrens Baylor College of Medicine
Jeffery W. Kelly
Jeffery W. Kelly Scripps Research Institute
Anton Berns
Anton Berns Antoni van Leeuwenhoek Hospital
Joan Heller Brown
Joan Heller Brown University of California, San Diego
Hugo A. Katus
Hugo A. Katus Heidelberg University

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