Peter H. Sugden

Overview

Best Publications

• Stimulation of the Stress-Activated Mitogen-Activated Protein Kinase Subfamilies in Perfused Heart: p38/RK Mitogen-Activated Protein Kinases and c-Jun N-Terminal Kinases Are Activated by Ischemia/Reperfusion

  Marie A. Bogoyevitch;Judith Gillespie-Brown;Albert J. Ketterman;Stephen J. Fuller

  784
  Citations

• “Stress-Responsive” Mitogen-Activated Protein Kinases (c-Jun N-Terminal Kinases and p38 Mitogen-Activated Protein Kinases) in the Myocardium

  Peter H. Sugden;Angela Clerk

  679
  Citations

• Endothelin-1 and fibroblast growth factors stimulate the mitogen-activated protein kinase signaling cascade in cardiac myocytes. The potential role of the cascade in the integration of two signaling pathways leading to myocyte hypertrophy.

  M A Bogoyevitch;P E Glennon;M B Andersson;Angela Clerk

  550
  Citations

• Cellular mechanisms of cardiac hypertrophy

  P. H. Sugden;Angela Clerk

  512
  Citations

• Cardiovascular side effects of cancer therapies: a position statement from the Heart Failure Association of the European Society of Cardiology.

  Thomas Eschenhagen;Thomas Force;Michael S. Ewer;Gilles W. De Keulenaer

  489
  Citations

• Regulation of the ERK subgroup of MAP kinase cascades through G protein-coupled receptors.

  Peter H Sugden;Angela Clerk

  464
  Citations

• Compartmentalization of adenosine 3':5'-monophosphate and adenosine 3':5'-monophosphate-dependent protein kinase in heart tissue.

  J D Corbin;P H Sugden;T M Lincoln;S L Keely

  458
  Citations

• Stimulation of “Stress-regulated” Mitogen-activated Protein Kinases (Stress-activated Protein Kinases/c-Jun N-terminal Kinases and p38-Mitogen-activated Protein Kinases) in Perfused Rat Hearts by Oxidative and Other Stresses

  Angela Clerk;Stephen J. Fuller;Ashour Michael;Peter H. Sugden

  452
  Citations

• Stimulation of the p38 Mitogen-activated Protein Kinase Pathway in Neonatal Rat Ventricular Myocytes by the G Protein–coupled Receptor Agonists, Endothelin-1 and Phenylephrine: A Role in Cardiac Myocyte Hypertrophy?

  Angela Clerk;Ashour Michael;Peter H. Sugden

  439
  Citations

• Purification and characterization of the catalytic subunit of adenosine 3':5'-cyclic monophosphate-dependent protein kinase from bovine liver.

  P H Sugden;L A Holladay;E M Reimann;J D Corbin

  406
  Citations

• Phenotyping Hypertrophy Eschew Obfuscation

  Gerald W. Dorn;Jeffrey Robbins;Peter H. Sugden

  400
  Citations

• Differential activation of protein kinase C isoforms by endothelin-1 and phenylephrine and subsequent stimulation of p42 and p44 mitogen-activated protein kinases in ventricular myocytes cultured from neonatal rat hearts.

  Angela Clerk;M A Bogoyevitch;M B Anderson;P H Sugden

  392
  Citations

• Characterization of protein kinase C isotype expression in adult rat heart. Protein kinase C-epsilon is a major isotype present, and it is activated by phorbol esters, epinephrine, and endothelin.

  M A Bogoyevitch;P J Parker;P H Sugden

  351
  Citations

• Regulation of Bcl-2 Family Proteins During Development and in Response to Oxidative Stress in Cardiac Myocytes Association With Changes in Mitochondrial Membrane Potential

  Stuart A. Cook;Peter H. Sugden;Angela Clerk

  348
  Citations

• Depletion of Mitogen-Activated Protein Kinase Using an Antisense Oligodeoxynucleotide Approach Downregulates the Phenylephrine-Induced Hypertrophic Response in Rat Cardiac Myocytes

  Peter E. Glennon;Samer Kaddoura;Elizabeth M. Sale;Graham J. Sale

  290
  Citations

• Signaling in myocardial hypertrophy: life after calcineurin?

  Peter H. Sugden

  287
  Citations

• Insulin-like Growth Factor-I Rapidly Activates Multiple Signal Transduction Pathways in Cultured Rat Cardiac Myocytes

  Rocı́o Foncea;Monica Andersson;Albert Ketterman;Vicky Blakesley

  277
  Citations

• Cellular Stresses Differentially Activate c-Jun N-terminal Protein Kinases and Extracellular Signal-regulated Protein Kinases in Cultured Ventricular Myocytes

  Marie A. Bogoyevitch;Albert J. Ketterman;Peter H. Sugden

  271
  Citations

• The p38-MAPK inhibitor, SB203580, inhibits cardiac stress-activated protein kinases/c-Jun N-terminal kinases (SAPKs/JNKs)

  Angela Clerk;Peter H Sugden

  271
  Citations

• Regulation of protein turnover in skeletal and cardiac muscle.

  P H Sugden;S J Fuller

  271
  Citations