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Biology and Biochemistry
UK
2026

D-Index & Metrics

Biology and Biochemistry

D-Index
107
Citations
60940
World Ranking
1075
National Ranking
57

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in United Kingdom Leader Award
  • 2025 - Research.com Biology and Biochemistry in United Kingdom Leader Award
  • 2018 - Fellow of the Royal Society, United Kingdom
  • 2015 - Member of Academia Europaea
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Member of the European Molecular Biology Organization (EMBO)
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Member of the European Molecular Biology Organization (EMBO)
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Richard Marais is affiliated with the University of Manchester in the United Kingdom. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a specific focus on Oncology, Molecular Biology, Immunology, Cancer Research, and Cell Biology.

The scientist's work covers several key topics, including:

  • Melanoma and MAPK Pathways
  • Cancer Immunotherapy and Biomarkers
  • CAR-T cell therapy research
  • Cutaneous Melanoma Detection and Management
  • Cancer Genomics and Diagnostics
  • Immunotherapy and Immune Responses
  • Single-cell and spatial transcriptomics

Recent publications authored or coauthored by Richard Marais include:

  • Cross-cohort gut microbiome associations with immune checkpoint inhibitor response in advanced melanoma, 2022, Nature Medicine
  • Single-cell analysis defines a pancreatic fibroblast lineage that supports anti-tumor immunity, 2021, Cancer Cell
  • Immune awakening revealed by peripheral T cell dynamics after one cycle of immunotherapy, 2020, Nature Cancer
  • Melanoma models for the next generation of therapies, 2021, Cancer Cell
  • The T cell receptor repertoire of tumor infiltrating T cells is predictive and prognostic for cancer survival, 2021, Nature Communications

Richard Marais frequently publishes in these venues:

  • Nature Communications
  • British Journal of Dermatology
  • European Journal of Cancer
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Medicine

The scientist has worked often with several collaborators, including:

  • Paul Lorigan
  • Piyushkumar A. Mundra
  • Sara Valpione
  • Nathalie Dhomen
  • Elena Galvani

Richard Marais has been recognized with several distinctions, such as:

  • Fellow of the Royal Society, United Kingdom, 2018
  • Member of Academia Europaea, 2015
  • Member of the European Molecular Biology Organization (EMBO)
  • Fellow of The Academy of Medical Sciences, United Kingdom

Best Publications

  • Mutations of the BRAF gene in human cancer

    Helen Davies;Graham R. Bignell;Charles Cox;Philip Stephens

  • Mechanism of Activation of the Raf-Erk Signaling Pathway by Oncogenic Mutations of B-Raf

    Paul T.C Wan;Mathew J Garnett;S.Mark Roe;Sharlene Lee

  • The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain

    Richard Marais;Judy Wynne;Richard Treisman

  • Melanoma biology and new targeted therapy

    Vanessa Gray-Schopfer;Claudia Wellbrock;Richard Marais

  • The RAF proteins take centre stage

    Claudia Wellbrock;Maria Karasarides;Richard Marais

  • Kinase-Dead BRAF and Oncogenic RAS Cooperate to Drive Tumor Progression through CRAF

    Sonja J. Heidorn;Carla Milagre;Steven Whittaker;Arnaud Nourry

  • RAS mutations in cutaneous squamous-cell carcinomas in patients treated with BRAF inhibitors.

    Fei Su;Amaya Viros;Carla Milagre;Kerstin Trunzer

  • Guilty as charged: B-RAF is a human oncogene

    Mathew J. Garnett;Richard Marais

  • Cyclooxygenase-Dependent Tumor Growth through Evasion of Immunity

    Santiago Zelenay;Annemarthe G. van der Veen;Jan P. Böttcher;Kathryn J. Snelgrove

  • Activation of the Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Pathway by Conventional, Novel, and Atypical Protein Kinase C Isotypes

    Dorothee C. Schönwasser;Richard M. Marais;Christopher J. Marshall;Peter J. Parker

  • Ras recruits Raf-1 to the plasma membrane for activation by tyrosine phosphorylation.

    R Marais;Y Light;H F Paterson;C J Marshall

  • The role of signaling pathways in the development and treatment of hepatocellular carcinoma.

    S Whittaker;R Marais;A X Zhu

  • Sorafenib in advanced melanoma: a Phase II randomised discontinuation trial analysis

    T Eisen;T Ahmad;K T Flaherty;M Gore

  • Oncogenic Braf induces melanocyte senescence and melanoma in mice.

    Nathalie Dhomen;Jorge S. Reis-Filho;Silvy da Rocha Dias;Robert Hayward

  • Differential Regulation of Raf-1, A-Raf, and B-Raf by Oncogenic Ras and Tyrosine Kinases

    Richard Marais;Yvonne Light;Hugh F. Paterson;Clive S. Mason

  • Intravital Imaging Reveals How BRAF Inhibition Generates Drug-Tolerant Microenvironments with High Integrin β1/FAK Signaling

    Eishu Hirata;Maria Romina Girotti;Amaya Viros;Steven Hooper

  • Serine and tyrosine phosphorylations cooperate in Raf-1, but not B-Raf activation

    Clive S. Mason;Caroline J. Springer;Robert G Cooper;Giulio Superti‐Furga

  • B-RAF is a therapeutic target in melanoma.

    Maria Karasarides;Antonio Chiloeches;Robert Hayward;Dan Niculescu-Duvaz

  • Requirement of Ras-GTP-Raf Complexes for Activation of Raf-1 by Protein Kinase C

    Richard Marais;Yvonne Light;Clive Mason;Hugh Paterson

  • V599EB-RAF is an Oncogene in Melanocytes

    Claudia Wellbrock;Lesley Ogilvie;Douglas Hedley;Maria Karasarides

Frequent Co-Authors

Paul Lorigan
Paul Lorigan University of Manchester
Christopher J. Marshall
Christopher J. Marshall Institute of Cancer Research
Peter J. Parker
Peter J. Parker The Francis Crick Institute
Jorge S. Reis-Filho
Jorge S. Reis-Filho Memorial Sloan Kettering Cancer Center
Samra Turajlic
Samra Turajlic Royal Marsden NHS Foundation Trust
James Larkin
James Larkin Royal Marsden NHS Foundation Trust
Hugh Paterson
Hugh Paterson Institute of Cancer Research
Caroline Dive
Caroline Dive University of Manchester
Erik Sahai
Erik Sahai The Francis Crick Institute
Martin Gore
Martin Gore Royal Marsden NHS Foundation Trust

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