Angela Clerk

Overview

Best Publications

• “Stress-Responsive” Mitogen-Activated Protein Kinases (c-Jun N-Terminal Kinases and p38 Mitogen-Activated Protein Kinases) in the Myocardium

  Peter H. Sugden;Angela Clerk

  679
  Citations

• Endothelin-1 and fibroblast growth factors stimulate the mitogen-activated protein kinase signaling cascade in cardiac myocytes. The potential role of the cascade in the integration of two signaling pathways leading to myocyte hypertrophy.

  M A Bogoyevitch;P E Glennon;M B Andersson;Angela Clerk

  550
  Citations

• Cellular mechanisms of cardiac hypertrophy

  P. H. Sugden;Angela Clerk

  512
  Citations

• Regulation of the ERK subgroup of MAP kinase cascades through G protein-coupled receptors.

  Peter H Sugden;Angela Clerk

  464
  Citations

• Stimulation of “Stress-regulated” Mitogen-activated Protein Kinases (Stress-activated Protein Kinases/c-Jun N-terminal Kinases and p38-Mitogen-activated Protein Kinases) in Perfused Rat Hearts by Oxidative and Other Stresses

  Angela Clerk;Stephen J. Fuller;Ashour Michael;Peter H. Sugden

  452
  Citations

• Stimulation of the p38 Mitogen-activated Protein Kinase Pathway in Neonatal Rat Ventricular Myocytes by the G Protein–coupled Receptor Agonists, Endothelin-1 and Phenylephrine: A Role in Cardiac Myocyte Hypertrophy?

  Angela Clerk;Ashour Michael;Peter H. Sugden

  439
  Citations

• Differential activation of protein kinase C isoforms by endothelin-1 and phenylephrine and subsequent stimulation of p42 and p44 mitogen-activated protein kinases in ventricular myocytes cultured from neonatal rat hearts.

  Angela Clerk;M A Bogoyevitch;M B Anderson;P H Sugden

  392
  Citations

• Regulation of Bcl-2 Family Proteins During Development and in Response to Oxidative Stress in Cardiac Myocytes Association With Changes in Mitochondrial Membrane Potential

  Stuart A. Cook;Peter H. Sugden;Angela Clerk

  348
  Citations

• The p38-MAPK inhibitor, SB203580, inhibits cardiac stress-activated protein kinases/c-Jun N-terminal kinases (SAPKs/JNKs)

  Angela Clerk;Peter H Sugden

  271
  Citations

• Activation of c-Jun N-terminal kinases and p38-mitogen-activated protein kinases in human heart failure secondary to ischaemic heart disease.

  Stuart A. Cook;Peter H. Sugden;Angela Clerk

  263
  Citations

• Stimulation of multiple mitogen-activated protein kinase sub-families by oxidative stress and phosphorylation of the small heat shock protein, HSP25/27, in neonatal ventricular myocytes

  Angela Clerk;Ashour Michael;Peter H. Sugden

  262
  Citations

• Glycogen synthase kinase 3 (GSK3) in the heart: a point of integration in hypertrophic signalling and a therapeutic target? A critical analysis.

  Peter H. Sugden;Stephen J. Fuller;S. C. Weiss;Angela Clerk

  251
  Citations

• Adrenergic receptor stimulation of the mitogen-activated protein kinase cascade and cardiac hypertrophy.

  Marie A. Bogoyevitch;Monica B. Andersson;Judith Gillespie-Brown;Angela Clerk

  226
  Citations

• Small Guanine Nucleotide-Binding Proteins and Myocardial Hypertrophy

  Angela Clerk;Peter H. Sugden

  201
  Citations

• Signaling pathways mediating cardiac myocyte gene expression in physiological and stress responses

  Angela Clerk;Timothy E. Cullingford;Stephen J. Fuller;Alejandro Giraldo

  193
  Citations

• Regulation of mitogen-activated protein kinases in cardiac myocytes through the small G protein Rac1.

  Angela Clerk;Fong H. Pham;Stephen J. Fuller;Erik Sahai

  192
  Citations

• PKC-dependent activation of p46/p54 JNKs during ischemic preconditioning in conscious rabbits

  Peipei Ping;Jun Zhang;Shuang Huang;Xinan Cao

  183
  Citations

• Dystrophin-related protein, utrophin, in normal and dystrophic human fetal skeletal muscle

  Angela Clerk;Glenn E. Morris;Victor Dubowitz;Kay E. Davies

  182
  Citations

• Activation of protein kinase cascades in the heart by hypertrophic G protein–coupled receptor agonists

  Angela Clerk;Peter H Sugden

  171
  Citations

• Kinases as therapeutic targets for heart failure

  Chris J. Vlahos;Susan A. McDowell;Angela Clerk

  170
  Citations