D-Index & Metrics Best Publications
Research.com 2022 Best Female Scientist Award Badge

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 97 Citations 31,159 275 World Ranking 794 National Ranking 493
Best female scientists D-index 101 Citations 33,862 422 World Ranking 861 National Ranking 536

Research.com Recognitions

Awards & Achievements

2022 - Research.com Best Female Scientist Award

Overview

What is she best known for?

The fields of study she is best known for:

  • Gene
  • Enzyme
  • Internal medicine

Daria Mochly-Rosen mostly deals with Protein kinase C, Biochemistry, Cell biology, Internal medicine and Receptors for Activated C Kinase. Her research in Protein kinase C intersects with topics in Isozyme, Pharmacology and Ischemia. Daria Mochly-Rosen combines subjects such as Genetically modified mouse, Knockout mouse and Programmed cell death with her study of Cell biology.

Her work deals with themes such as Endocrinology, In vivo and Cardiology, which intersect with Internal medicine. Her Receptors for Activated C Kinase research incorporates elements of Binding protein, Proto-oncogene tyrosine-protein kinase Src, Binding site and Receptor for activated C kinase 1. Her study in Enzyme activator is interdisciplinary in nature, drawing from both ALDH2 and Aldehyde dehydrogenase.

Her most cited work include:

  • Localization of protein kinases by anchoring proteins: A theme in signal transduction (867 citations)
  • Cloning of an intracellular receptor for protein kinase C: a homolog of the beta subunit of G proteins. (667 citations)
  • Protein kinase C isozymes and the regulation of diverse cell responses (661 citations)

What are the main themes of her work throughout her whole career to date?

Protein kinase C, Biochemistry, Cell biology, Pharmacology and Internal medicine are her primary areas of study. As a member of one scientific family, Daria Mochly-Rosen mostly works in the field of Protein kinase C, focusing on Protein kinase A and, on occasion, Molecular biology. Her is doing research in Aldehyde dehydrogenase, ALDH2, Receptors for Activated C Kinase, Phosphorylation and Enzyme, both of which are found in Biochemistry.

Her Cell biology research includes themes of Apoptosis, Programmed cell death and Cell. Her Pharmacology study combines topics from a wide range of disciplines, such as Anesthesia, Reperfusion injury, Cardioprotection, Ischemia and Activator. Her Internal medicine study integrates concerns from other disciplines, such as Endocrinology and Cardiology.

She most often published in these fields:

  • Protein kinase C (40.90%)
  • Biochemistry (29.79%)
  • Cell biology (22.70%)

What were the highlights of her more recent work (between 2015-2021)?

  • Aldehyde dehydrogenase (12.29%)
  • ALDH2 (11.35%)
  • Mitochondrion (10.17%)

In recent papers she was focusing on the following fields of study:

Her main research concerns Aldehyde dehydrogenase, ALDH2, Mitochondrion, Cell biology and Biochemistry. Daria Mochly-Rosen combines subjects such as Cancer research, Acetaldehyde, Stem cell, Pharmacology and In vivo with her study of Aldehyde dehydrogenase. In her study, Diabetic cardiomyopathy is strongly linked to Endocrinology, which falls under the umbrella field of ALDH2.

Her research in Cell biology intersects with topics in mitochondrial fusion, MFN2 and Peptide. Her is involved in several facets of Biochemistry study, as is seen by her studies on Phosphorylation, Protein kinase C, Enzyme, Glucose-6-phosphate dehydrogenase and Protein kinase A. Daria Mochly-Rosen has researched Protein kinase C in several fields, including Biophysics and Substrate.

Between 2015 and 2021, her most popular works were:

  • Fragmented mitochondria released from microglia trigger A1 astrocytic response and propagate inflammatory neurodegeneration (128 citations)
  • Correcting mitochondrial fusion by manipulating mitofusin conformations (122 citations)
  • Macrophage de novo NAD+ synthesis specifies immune function in aging and inflammation. (118 citations)

In her most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Internal medicine

Daria Mochly-Rosen focuses on Mitochondrion, Cell biology, Oxidative stress, Neurodegeneration and Internal medicine. Daria Mochly-Rosen has included themes like Enzyme activator, Pharmacology, Bioinformatics and FIS1 in her Oxidative stress study. Her work on Endocrinology expands to the thematically related Internal medicine.

Her Programmed cell death research includes elements of Myocyte, Cardiac myocyte, MFN1, Neuroinflammation and Protein kinase C. Daria Mochly-Rosen performs multidisciplinary study in Acrolein and Biochemistry in her work. Her studies in Biochemistry integrate themes in fields like Molecular biology and Computational biology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Localization of protein kinases by anchoring proteins: A theme in signal transduction

Daria Mochly-Rosen.
Science (1995)

1119 Citations

Protein kinase C isozymes and the regulation of diverse cell responses

Edward C. Dempsey;Edward C. Dempsey;Alexandra C. Newton;Daria Mochly-Rosen;Alan P. Fields.
American Journal of Physiology-lung Cellular and Molecular Physiology (2000)

1000 Citations

Cloning of an intracellular receptor for protein kinase C: a homolog of the beta subunit of G proteins.

Dorit Ron;Che-Hong Chen;Jeremy Caldwell;Lee Jamieson.
Proceedings of the National Academy of Sciences of the United States of America (1994)

853 Citations

Anchoring proteins for protein kinase C: a means for isozyme selectivity

Daria Mochly-Rosen;Adrienne S. Gordon.
The FASEB Journal (1998)

724 Citations

Activation of Aldehyde Dehydrogenase-2 Reduces Ischemic Damage to the Heart

Che Hong Chen;Grant R. Budas;Eric N. Churchill;Marie Hélène Disatnik.
Science (2008)

711 Citations

Identification of intracellular receptor proteins for activated protein kinase C.

Daria Mochly-Rosen;Hanita Khaner;Jamie Lopez.
Proceedings of the National Academy of Sciences of the United States of America (1991)

647 Citations

Opposing cardioprotective actions and parallel hypertrophic effects of δPKC and ɛPKC

Leon Chen;Harvey Hahn;Guangyu Wu;Che Hong Chen.
Proceedings of the National Academy of Sciences of the United States of America (2001)

607 Citations

Protein kinase C, an elusive therapeutic target?

Daria Mochly-Rosen;Kanad Das;Kevin V. Grimes.
Nature Reviews Drug Discovery (2012)

508 Citations

Localization of protein kinase C isozymes in cardiac myocytes.

Marie-Helene Disatnik;Giorgio Buraggi;Daria Mochly-Rosen.
Experimental Cell Research (1994)

464 Citations

A Selective ε-Protein Kinase C Antagonist Inhibits Protection of Cardiac Myocytes from Hypoxia-induced Cell Death

Mary O. Gray;Joel S. Karliner;Daria Mochly-Rosen.
Journal of Biological Chemistry (1997)

463 Citations

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