Daniel E. Koshland

Overview

Best Publications

• Comparison of experimental binding data and theoretical models in proteins containing subunits.

  D. E. Koshland;G. Némethy;D. Filmer

  4400
  Citations

• Application of a Theory of Enzyme Specificity to Protein Synthesis

  Koshland De

  3186
  Citations

• An amplified sensitivity arising from covalent modification in biological systems

  Albert Goldbeter;Daniel E. Koshland

  1439
  Citations

• STEREOCHEMISTRY AND THE MECHANISM OF ENZYMATIC REACTIONS

  D. E. Koshland

  1343
  Citations

• A Method for the Quantitative Modification and Estimation of Carboxylic Acid Groups in Proteins

  D.G. Hoare;D.E. Koshland

  1314
  Citations

• The Gradient-Sensing Mechanism in Bacterial Chemotaxis

  Robert M. Macnab;D. E. Koshland

  1251
  Citations

• NO news is good news

  Elizabeth Culotta;Daniel E. Koshland

  1099
  Citations

• The Key–Lock Theory and the Induced Fit Theory

  Daniel E. Koshland

  850
  Citations

• The Molecule of the Year

  Ruth Levy Guyer;Daniel E. Koshland

  812
  Citations

• Non-genetic individuality: chance in the single cell

  John L. Spudich;D. E. Koshland

  652
  Citations

• Negative cooperativity in enzyme action. The binding of diphosphopyridine nucleotide to glyceraldehyde 3-phosphate dehydrogenase.

  Abby. Conway;Daniel E. Koshland

  620
  Citations

• Amplification and adaptation in regulatory and sensory systems

  Daniel E. Koshland;Albert Goldbeter;Jeffry B. Stock

  573
  Citations

• NEGATIVE COOPERATIVITY IN REGULATORY ENZYMES

  Alexander Levitzki;D. E. Koshland

  554
  Citations

• Three-dimensional structures of the ligand-binding domain of the bacterial aspartate receptor with and without a ligand.

  Michael V. Milburn;Gilbert G. Prive;Daniel L. Milligan;William G. Scott

  515
  Citations

• Structural basis of multiple drug-binding capacity of the AcrB multidrug efflux pump.

  Edward W. Yu;Gerry McDermott;Helen I. Zgurskaya;Hiroshi Nikaido

  493
  Citations

• Identification of the site of phosphorylation of the chemotaxis response regulator protein, CheY.

  D A Sanders;B L Gillece-Castro;A M Stock;A L Burlingame

  425
  Citations

• Inactivation of isocitrate dehydrogenase by phosphorylation is mediated by the negative charge of the phosphate.

  P E Thorsness;D E Koshland

  406
  Citations

• A colorimetric procedure for the quantitative determination of tryptophan residues in proteins.

  T.E. Barman;D.E. Koshland

  396
  Citations

• Protein kinase C directly phosphorylates the insulin receptor in vitro and reduces its protein-tyrosine kinase activity

  Gideon E. Bollag;Richard A. Roth;Jacqueline Beaudoin;Daria Mochly-Rosen

  375
  Citations

• A piston model for transmembrane signaling of the aspartate receptor.

  Karen M. Ottemann;Wenzhong Xiao;Yeon-Kyun Shin;Daniel E. Koshland

  358
  Citations