World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
73
Citations
21708
World Ranking
19614
National Ranking
9768

Overview

Douglas B. Sawyer is affiliated with Maine Medical Center in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, contributing notably to Cardiology and Cardiovascular Medicine, Molecular Biology, Oncology, Surgery, and Critical Care and Intensive Care Medicine.

The scientist's recent publications reflect a strong focus on cardiovascular health and disease mechanisms, with an emphasis on molecular and cellular approaches. Their selected works include:

  • 3D Co-culture of hiPSC-Derived Cardiomyocytes With Cardiac Fibroblasts Improves Tissue-Like Features of Cardiac Spheroids, 2020, Frontiers in Molecular Biosciences
  • Common mechanistic pathways in cancer and heart failure. A scientific roadmap on behalf of the Translational Research Committee of the Heart Failure Association (HFA) of the European Society of Cardiology (ESC), 2020, European Journal of Heart Failure
  • Neuregulins: protective and reparative growth factors in multiple forms of cardiovascular disease, 2020, Clinical Science
  • Prolonged Cardiopulmonary Bypass is Associated With Endothelial Glycocalyx Degradation, 2020, Journal of Surgical Research
  • Cardiovascular disease associated with methamphetamine use: a review, 2022, Heart Failure Reviews

Frequent co-authors collaborating with Douglas B. Sawyer include:

  • Sergey Ryzhov
  • Joanne T. deKay
  • Teresa May
  • Richard R. Riker
  • David B. Seder

The scientist's publications are often found in journals such as:

  • Circulation
  • Circulation Research
  • The FASEB Journal
  • Journal of Maine Medical Center
  • Frontiers in Molecular Biosciences

Main topics of Douglas B. Sawyer's work include:

  • Cardiac Fibrosis and Remodeling
  • Signaling Pathways in Disease
  • Cardiac Arrest and Resuscitation
  • Heart Failure Treatment and Management
  • Tissue Engineering and Regenerative Medicine
  • Chemotherapy-induced cardiotoxicity and mitigation
  • HER2/EGFR in Cancer Research

Best Publications

  • Inflammatory Markers and Risk of Heart Failure in Elderly Subjects Without Prior Myocardial Infarction The Framingham Heart Study

    Ramachandran S. Vasan;Lisa M. Sullivan;Ronenn Roubenoff;Charles A. Dinarello

  • Opposing effects of beta(1)- and beta(2)-adrenergic receptors on cardiac myocyte apoptosis : role of a pertussis toxin-sensitive G protein.

    Catherine Communal;Krishna Singh;Douglas B. Sawyer;Wilson S. Colucci

  • Role of Oxidative Stress in Myocardial Hypertrophy and Failure

    Douglas B. Sawyer;Deborah A. Siwik;Lei Xiao;David R. Pimentel

  • Anthracycline Cardiotoxicity: From Bench to Bedside

    Luca Gianni;Eugene H. Herman;Steven E. Lipshultz;Giorgio Minotti

  • Cardiovascular side effects of cancer therapies: a position statement from the Heart Failure Association of the European Society of Cardiology.

    Thomas Eschenhagen;Thomas Force;Michael S. Ewer;Gilles W. De Keulenaer

  • Cell Therapy Attenuates Deleterious Ventricular Remodeling and Improves Cardiac Performance After Myocardial Infarction

    Mohit Jain;Harout DerSimonian;Daniel A. Brenner;Soeun Ngoy

  • Vascular Endothelial Growth Factor Blockade Promotes the Transition From Compensatory Cardiac Hypertrophy to Failure in Response to Pressure Overload

    Yasuhiro Izumiya;Ichiro Shiojima;Kaori Sato;Douglas B. Sawyer

  • Cardio-Oncology: An Update on Cardiotoxicity of Cancer-Related Treatment.

    Carrie G. Lenneman;Douglas B. Sawyer

  • Modulation of anthracycline-induced myofibrillar disarray in rat ventricular myocytes by neuregulin-1beta and anti-erbB2: potential mechanism for trastuzumab-induced cardiotoxicity.

    Douglas B. Sawyer;Christian Zuppinger;Thomas A. Miller;Hans M. Eppenberger

  • Reactive Oxygen Species Mediate Amplitude-Dependent Hypertrophic and Apoptotic Responses to Mechanical Stretch in Cardiac Myocytes

    David R. Pimentel;Jay K. Amin;Lei Xiao;Thomas Miller

  • Exaggerated Left Ventricular Dilation and Reduced Collagen Deposition After Myocardial Infarction in Mice Lacking Osteopontin

    Nathan A. Trueblood;Zhonglin Xie;Catherine Communal;Flora Sam

  • Serum Insulin-like Growth Factor I and Risk for Heart Failure in Elderly Individuals without a Previous Myocardial Infarction: The Framingham Heart Study

    Ramachandran S Vasan;Lisa M Sullivan;Ralph B D'Agostino;Ronenn Roubenoff

  • H2O2 regulates cardiac myocyte phenotype via concentration-dependent activation of distinct kinase pathways

    Susan H. Kwon;David R. Pimentel;Andrea Remondino;Douglas B. Sawyer

  • β-Adrenergic Receptor–Stimulated Apoptosis in Cardiac Myocytes Is Mediated by Reactive Oxygen Species/c-Jun NH2-Terminal Kinase–Dependent Activation of the Mitochondrial Pathway

    Andrea Remondino;Susan H. Kwon;Catherine Communal;David R. Pimentel

  • Transgenic Mice Overexpressing Mutant PRKAG2 Define the Cause of Wolff-Parkinson-White Syndrome in Glycogen Storage Cardiomyopathy

    Michael Arad;Ivan P. Moskowitz;Vickas V. Patel;Ferhaan Ahmad

  • Amyloidogenic light chains induce cardiomyocyte contractile dysfunction and apoptosis via a non-canonical p38α MAPK pathway

    Jianru Shi;Jian Guan;Bingbing Jiang;Daniel A. Brenner

  • Anthracyclines induce calpain-dependent titin proteolysis and necrosis in cardiomyocytes.

    Chee Chew Lim;Christian Zuppinger;Xinxin Guo;Gabriela M. Kuster

  • Role of reactive oxygen species and NAD(P)H oxidase in α1-adrenoceptor signaling in adult rat cardiac myocytes

    Lei Xiao;David R. Pimentel;Jing Wang;Krishna Singh

  • Inhibition of Copper-Zinc Superoxide Dismutase Induces Cell Growth, Hypertrophic Phenotype, and Apoptosis in Neonatal Rat Cardiac Myocytes In Vitro

    Deborah A. Siwik;John D. Tzortzis;David R. Pimental;Donny L.-F. Chang

  • Neuregulin in Cardiovascular Development and Disease

    Oghenerukevwe Odiete;Michael F. Hill;Douglas B. Sawyer

Frequent Co-Authors

Wilson S. Colucci
Wilson S. Colucci Boston University
Ronglih Liao
Ronglih Liao Stanford University
Ramachandran S. Vasan
Ramachandran S. Vasan The University of Texas Health Science Center at San Antonio
Krishna Singh
Krishna Singh East Tennessee State University
Sean P. Collins
Sean P. Collins Vanderbilt University Medical Center
Frank E. Harrell
Frank E. Harrell Vanderbilt University
Mohit Jain
Mohit Jain University of California, San Diego
Lisa M. Sullivan
Lisa M. Sullivan Boston University
Stuart K. Calderwood
Stuart K. Calderwood Beth Israel Deaconess Medical Center

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring medicine in the USA often opens doors to a wide range of online nursing programs and degree pathways. For those seeking a quick and affordable entry, the cheapest accredited online rn to bsn programs allow registered nurses to advance their credentials flexibly and economically.

If you already possess a non-nursing bachelor’s degree, direct entry msn programs for non nurses online offer a fast-track route to become a master’s-level nurse without starting from scratch.

For those interested in teaching or leadership, numerous doctorate in nursing education online programs provide advanced credentials that can lead to roles in academia or healthcare administration.

Finally, individuals looking for accessible entry points can consider what is the easiest nursing program to get into. These programs help students begin their healthcare journey with lower barriers to admission.

Each pathway offers unique benefits, allowing future medical professionals to choose options that best suit their goals, schedules, and budgets.

Best Scientists Citing Douglas B. Sawyer

Trending Scientists