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Medicine

D-Index
94
Citations
39382
World Ranking
10349
National Ranking
5323

Overview

Hedy L. Kindler is affiliated with the University of Chicago in the United States, contributing extensively to medical research with a focus on oncology. Their body of work encompasses over 300 publications predominantly in the field of medicine, with particular emphasis on oncology and pulmonary and respiratory medicine.

Their research spans various subfields including oncology, pulmonary and respiratory medicine, cancer research, surgery, and radiology, nuclear medicine, and imaging. Key topics covered by their research include occupational and environmental lung diseases, pancreatic and hepatic oncology, pleural and pulmonary diseases, cancer genomics and diagnostics, cancer immunotherapy and biomarkers, PARP inhibition in cancer therapy, and cancer research and treatments.

Notable recent publications by Hedy L. Kindler include:

  • Overall Survival Results From the POLO Trial: A Phase III Study of Active Maintenance Olaparib Versus Placebo for Germline BRCA-Mutated Metastatic Pancreatic Cancer (2022, Journal of Clinical Oncology)
  • Association of tumour mutational burden with outcomes in patients with advanced solid tumours treated with pembrolizumab: prospective biomarker analysis of the multicohort, open-label, phase 2 KEYNOTE-158 study (2020, The Lancet Oncology)
  • Randomized, Multicenter, Phase II Trial of Gemcitabine and Cisplatin With or Without Veliparib in Patients With Pancreas Adenocarcinoma and a Germline BRCA/PALB2 Mutation (2020, Journal of Clinical Oncology)
  • First-in-Human, Multicenter, Phase I Dose-Escalation and Expansion Study of Anti-Mesothelin Antibody-Drug Conjugate Anetumab Ravtansine in Advanced or Metastatic Solid Tumors (2020, Journal of Clinical Oncology)
  • Durvalumab with platinum-pemetrexed for unresectable pleural mesothelioma: survival, genomic and immunologic analyses from the phase 2 PrE0505 trial (2021, Nature Medicine)

Hedy L. Kindler frequently publishes in the following venues:

  • Journal of Clinical Oncology
  • Journal of Thoracic Oncology
  • UNC Libraries
  • Annals of Oncology
  • Annals of Surgical Oncology

Frequent coauthors with whom Kindler has collaborated include:

  • Talia Golan
  • Eileen M. O'Reilly
  • Gershon Y. Locker
  • Kiran K. Turaga
  • David McGuinness

Their work in oncology research touches on clinical trials, biomarker analysis, and novel cancer therapeutics. The research outputs also indicate involvement in advanced therapies for pancreatic cancer, mesothelioma, and solid tumors, with an interdisciplinary approach combining clinical oncology, genomics, and pharmacological treatments.

Best Publications

  • The IASLC Lung Cancer Staging Project: Proposals for Revision of the TNM Stage Groupings in the Forthcoming (Eighth) Edition of the TNM Classification for Lung Cancer.

    Peter Goldstraw;Kari Chansky;John Crowley;Ramon Rami-Porta

  • Association of tumour mutational burden with outcomes in patients with advanced solid tumours treated with pembrolizumab: prospective biomarker analysis of the multicohort, open-label, phase 2 KEYNOTE-158 study.

    Aurélien Marabelle;Marwan Fakih;Juanita Lopez;Manisha Shah

  • Maintenance Olaparib for Germline BRCA-Mutated Metastatic Pancreatic Cancer

    Talia Golan;Pascal Hammel;Michele Reni;Eric Van Cutsem

  • Gemcitabine Plus Bevacizumab Compared With Gemcitabine Plus Placebo in Patients With Advanced Pancreatic Cancer: Phase III Trial of the Cancer and Leukemia Group B (CALGB 80303)

    Hedy Lee Kindler;Donna Niedzwiecki;Donna Hollis;Susan Sutherland

  • The IASLC Lung Cancer Staging Project: Proposals for Coding T Categories for Subsolid Nodules and Assessment of Tumor Size in Part-Solid Tumors in the Forthcoming Eighth Edition of the TNM Classification of Lung Cancer

    William D. Travis;Hisao Asamura;Alexander A. Bankier;Mary Beth Beasley

  • Phase II Trial of Bevacizumab Plus Gemcitabine in Patients With Advanced Pancreatic Cancer

    Hedy L. Kindler;Gregory Friberg;Deepti A. Singh;Gershon Locker

  • Integrative Molecular Characterization of Malignant Pleural Mesothelioma

    Julija Hmeljak;Francisco Sanchez-Vega;Katherine A. Hoadley;Juliann Shih

  • Multicenter Phase II Trial of Neoadjuvant Pemetrexed Plus Cisplatin Followed by Extrapleural Pneumonectomy and Radiation for Malignant Pleural Mesothelioma

    Lee M. Krug;Harvey I. Pass;Valerie W. Rusch;Hedy L. Kindler

  • Phase I Study of SS1P, a Recombinant Anti-Mesothelin Immunotoxin Given as a Bolus I.V. Infusion to Patients with Mesothelin-Expressing Mesothelioma, Ovarian, and Pancreatic Cancers

    Raffit Hassan;Susie Bullock;Ahalya Premkumar;Robert J. Kreitman

  • Randomized Phase II Trial of Cetuximab, Bevacizumab, and Irinotecan Compared With Cetuximab and Bevacizumab Alone in Irinotecan-Refractory Colorectal Cancer: The BOND-2 Study

    Leonard B. Saltz;Heinz-Josef Lenz;Hedy L. Kindler;Howard S. Hochster

  • Randomized Phase Ib/II Study of Gemcitabine Plus Placebo or Vismodegib, a Hedgehog Pathway Inhibitor, in Patients With Metastatic Pancreatic Cancer

    Daniel V.T. Catenacci;Melissa R. Junttila;Theodore Karrison;Nathan Bahary

  • Preoperative Modified FOLFIRINOX Treatment Followed by Capecitabine-Based Chemoradiation for Borderline Resectable Pancreatic Cancer: Alliance for Clinical Trials in Oncology Trial A021101.

    Matthew H.G. Katz;Qian Shi;Syed A. Ahmad;Joseph M. Herman

  • Tremelimumab as second-line or third-line treatment in relapsed malignant mesothelioma (DETERMINE): a multicentre, international, randomised, double-blind, placebo-controlled phase 2b trial.

    Michele Maio;Arnaud Scherpereel;Luana Calabrò;Joachim Aerts

  • Axitinib plus gemcitabine versus placebo plus gemcitabine in patients with advanced pancreatic adenocarcinoma: a double-blind randomised phase 3 study

    Hedy L Kindler;Tatsuya Ioka;Dirk J Richel;Jaafar Bennouna

  • Malignant pleural mesothelioma

    Anne S. Tsao;Ignacio Wistuba;Jack A. Roth;Hedy Lee Kindler

  • Reduction of Cisplatin-Induced Emesis by a Selective Neurokinin-1–Receptor Antagonist

    Rudolph M. Navari;Rick R. Reinhardt;Richard J. Gralla;Mark G. Kris

  • A phase III trial of pemetrexed plus gemcitabine versus gemcitabine in patients with unresectable or metastatic pancreatic cancer.

    Helmut Oettle;D. Richards;R. K. Ramanathan;J. L. van Laethem

  • Treatment of Malignant Pleural Mesothelioma: American Society of Clinical Oncology Clinical Practice Guideline

    Hedy L. Kindler;Nofisat Ismaila;Samuel G. Armato;Raphael Bueno

  • Phase II Study of Pemetrexed With and Without Folic Acid and Vitamin B12 as Front-Line Therapy in Malignant Pleural Mesothelioma

    Giorgio V. Scagliotti;Dong-M. Shin;Hedy L. Kindler;Michael J. Vasconcelles

  • A double-blind, placebo-controlled, randomized phase III trial of gemcitabine (G) plus bevacizumab (B) versus gemcitabine plus placebo (P) in patients (pts) with advanced pancreatic cancer (PC): A preliminary analysis of Cancer and Leukemia Group B (CALGB

    H. L. Kindler;D. Niedzwiecki;D. Hollis;E. Oraefo

Frequent Co-Authors

Theodore Karrison
Theodore Karrison University of Chicago
Eileen M. O’Reilly
Eileen M. O’Reilly Memorial Sloan Kettering Cancer Center
Alan P. Venook
Alan P. Venook University of California, San Francisco
Everett E. Vokes
Everett E. Vokes University of Chicago
Donna Niedzwiecki
Donna Niedzwiecki Duke University
Ravi Salgia
Ravi Salgia City Of Hope National Medical Center
Anna K. Nowak
Anna K. Nowak University of Western Australia
Walter M. Stadler
Walter M. Stadler University of Chicago
Mark J. Ratain
Mark J. Ratain University of Chicago

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