Peter Penzes mainly investigates Neuroscience, Dendritic spine, Cell biology, Dendritic spine morphogenesis and Neurotransmission. His work carried out in the field of Neuroscience brings together such families of science as NMDA receptor, Glutamatergic, Disease and Schizophrenia. He interconnects Endophenotype, AMPA receptor, Signal transduction, Alzheimer's disease and Synapse in the investigation of issues within Dendritic spine.
His Cell biology study incorporates themes from Morphogenesis, Actin cytoskeleton and Postsynaptic density. The study incorporates disciplines such as Synaptic plasticity and Receptor in addition to Dendritic spine morphogenesis. In his research, DISC1, Metaplasticity and Synapse maturation is intimately related to Glutamate receptor, which falls under the overarching field of Neurotransmission.
His primary areas of investigation include Dendritic spine, Neuroscience, Cell biology, Excitatory postsynaptic potential and Synaptic plasticity. He studied Dendritic spine and Small GTPase that intersect with Corticotropin-releasing hormone. Peter Penzes has included themes like Schizophrenia, Signal transduction, Glutamatergic and Disease in his Neuroscience study.
The various areas that Peter Penzes examines in his Schizophrenia study include Alzheimer's disease, Regulation of gene expression, Autism and Auditory cortex. His Glutamatergic research incorporates themes from Neurotransmission and DISC1. His Cell biology research is multidisciplinary, relying on both Ankyrin and Actin cytoskeleton.
Peter Penzes mainly focuses on Cell biology, Dendritic spine, Neuroscience, Excitatory postsynaptic potential and Ankyrin. The Cell biology study combines topics in areas such as CNTNAP2 and Cerebrospinal fluid. His studies deal with areas such as Synaptic plasticity, Excitatory synapse, Guanine nucleotide exchange factor and Small GTPase as well as Dendritic spine.
His work on Synapse as part of general Neuroscience study is frequently linked to Induced pluripotent stem cell, bridging the gap between disciplines. His study in Excitatory postsynaptic potential is interdisciplinary in nature, drawing from both AMPA receptor, Glutamatergic and Balance. His Ankyrin research is multidisciplinary, incorporating elements of HOMER1 and Gene isoform.
His primary areas of study are Cell biology, Dendritic spine, Neuroscience, Excitatory postsynaptic potential and AMPA receptor. Peter Penzes focuses mostly in the field of Cell biology, narrowing it down to topics relating to Ankyrin and, in certain cases, Scaffold protein, Dendrite and Axon initial segment. In his study, Vesicular glutamate transporter 1, Guanine nucleotide exchange factor, Dendritic spine morphogenesis, Synapse and Hippocampal formation is strongly linked to Small GTPase, which falls under the umbrella field of Dendritic spine.
The concepts of his Neuroscience study are interwoven with issues in Missense mutation, Amyloid beta and Dysgenesis. Peter Penzes usually deals with Excitatory postsynaptic potential and limits it to topics linked to Glutamatergic and Colocalization, Neurotransmission, Schizophrenia and DISC1. His studies in AMPA receptor integrate themes in fields like Inhibitory postsynaptic potential and Postsynaptic potential.
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Dendritic spine pathology in neuropsychiatric disorders
Peter Penzes;Michael E. Cahill;Kelly A. Jones;Jon Eric Vanleeuwen.
Nature Neuroscience (2011)
Rapid induction of dendritic spine morphogenesis by trans-synaptic ephrinB-EphB receptor activation of the Rho-GEF kalirin.
Peter Penzes;Alexander Beeser;Jonathan Chernoff;Martin R. Schiller.
Neuron (2003)
The neuronal Rho-GEF Kalirin-7 interacts with PDZ domain-containing proteins and regulates dendritic morphogenesis.
Peter Penzes;Richard C. Johnson;Rita Sattler;Xiaoqun Zhang.
Neuron (2001)
Disrupted-in-Schizophrenia 1 (DISC1) regulates spines of the glutamate synapse via Rac1
Akiko Hayashi-Takagi;Manabu Takaki;Nick Graziane;Saurav Seshadri.
Nature Neuroscience (2010)
Kalirin-7 controls activity-dependent structural and functional plasticity of dendritic spines
Zhong Xie;Deepak P. Srivastava;Huzefa Photowala;Li Kai.
Neuron (2007)
Common mechanisms of excitatory and inhibitory imbalance in schizophrenia and autism spectrum disorders.
R. Gao;P. Penzes.
Current Molecular Medicine (2015)
Dendritic Structural Plasticity and Neuropsychiatric Disease
Marc P. Forrest;Euan Parnell;Peter Penzes.
Nature Reviews Neuroscience (2018)
Cloning of a cDNA encoding an aldehyde dehydrogenase and its expression in Escherichia coli. Recognition of retinal as substrate.
Xianshu Wang;Peter Penzes;Joseph L. Napoli.
Journal of Biological Chemistry (1996)
An Isoform of Kalirin, a Brain-specific GDP/GTP Exchange Factor, Is Enriched in the Postsynaptic Density Fraction
Peter Penzes;Richard C. Johnson;M.Rashid Alam;Vikram Kambampati.
Journal of Biological Chemistry (2000)
Kalirin regulates cortical spine morphogenesis and disease-related behavioral phenotypes.
Michael E. Cahill;Zhong Xie;Michelle Day;Huzefa Photowala.
Proceedings of the National Academy of Sciences of the United States of America (2009)
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