Andrew F. Wilks

Overview

Best Publications

• Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and VEGF receptor 3 (Flt4)

  Marc G. Achen;Michael Jeltsch;Eola Kukk;Taija Mäkinen

  1685
  Citations

• Association of transcription factor APRF and protein kinase Jak1 with the interleukin-6 signal transducer gp130.

  Claudia Lütticken;Ursula M. Wegenka;Juping Yuan;Jan Buschmann

  1031
  Citations

• The protein tyrosine kinase JAK1 complements defects in interferon-α/β and -γ signal transduction

  Mathias Müller;James Briscoe;Carl Laxton;Dmitry Guschin

  938
  Citations

• Two novel protein-tyrosine kinases, each with a second phosphotransferase-related catalytic domain, define a new class of protein kinase.

  A F Wilks;A G Harpur;R R Kurban;S J Ralph

  673
  Citations

• Polypeptide signalling to the nucleus through tyrosine phosphorylation of Jak and Stat proteins

  Ke Shuai;Andrew Ziemiecki;Andrew F. Wilks;Ailsa G. Harpur

  580
  Citations

• Inhibition of Growth of C6 Glioma Cells in Vivo by Expression of Antisense Vascular Endothelial Growth Factor Sequence

  Mary Saleh;Steven A. Stacker;Andrew F. Wilks

  571
  Citations

• Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death

  Joanne M. Hildebrand;Maria C. Tanzer;Isabelle S. Lucet;Isabelle S. Lucet;Samuel N. Young

  553
  Citations

• Two putative protein-tyrosine kinases identified by application of the polymerase chain reaction.

  Andrew F. Wilks

  549
  Citations

• Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.

  Wesley C. Van Voorhis;John H. Adams;Roberto Adelfio;Roberto Adelfio;Vida Ahyong

  425
  Citations

• JAK2, a third member of the JAK family of protein tyrosine kinases.

  A G Harpur;A C Andres;A Ziemiecki;R R Aston

  384
  Citations

• The structural basis of Janus kinase 2 inhibition by a potent and specific pan-Janus kinase inhibitor

  Isabelle S Lucet;Emmanuelle Fantino;Emmanuelle Fantino;Michelle Styles;Michelle Styles;Rebecca Samantha Bamert;Rebecca Samantha Bamert

  329
  Citations

• Two forms of the basic fibroblast growth factor receptor-like mRNA are expressed in the developing mouse brain.

  Hugh H. Reid;Andrew F. Wilks;Ora Bernard

  290
  Citations

• Dissecting specificity in the Janus kinases: the structures of JAK-specific inhibitors complexed to the JAK1 and JAK2 protein tyrosine kinase domains.

  Neal Kenneth Williams;Rebecca Samantha Bamert;Onisha Patel;Chunxiao Wang

  264
  Citations

• Tyrosine kinase JAK1 is associated with the granulocyte-colony-stimulating factor receptor and both become tyrosine-phosphorylated after receptor activation.

  Sandra E. Nicholson;Andrew C. Oates;Ailsa G. Harpur;Andrew Ziemiecki

  263
  Citations

• Kinase-negative mutants of JAK1 can sustain interferon-gamma-inducible gene expression but not an antiviral state.

  James Briscoe;Neil C. Rogers;Bruce A. Witthuhn;Diane Watling

  256
  Citations

• Interferon-gamma induces tyrosine phosphorylation of interferon-gamma receptor and regulated association of protein tyrosine kinases, Jak1 and Jak2, with its receptor.

  K. Igarashi;G. Garotta;L. Ozmen;A. Ziemiecki

  254
  Citations

• Ryk-deficient mice exhibit craniofacial defects associated with perturbed Eph receptor crosstalk

  Michael M. Halford;Michael M. Halford;Michael M. Halford;Jane Armes;Michael Buchert;Virginia Meskenaite

  233
  Citations

• Identification of JAK protein tyrosine kinases as signaling molecules for prolactin. Functional analysis of prolactin receptor and prolactin-erythropoietin receptor chimera expressed in lymphoid cells.

  I Dusanter-Fourt;O Muller;A Ziemiecki;P Mayeux

  222
  Citations

• Methods of inhibiting kinases

  Christopher John Burns;Andrew Frederick Wilks

  217
  Citations

• Pharmaceutical compositions comprising a VEGF-D polypeptide

  Marc G. Achen;Stephen A. Stacker;Kari Alitalo;Andrew F. Wilks

  216
  Citations