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Neuroscience

D-Index
99
Citations
37358
World Ranking
778
National Ranking
429

Research.com Recognitions

  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Akira Sawa is affiliated with Johns Hopkins University in the United States. Their research spans multiple interconnected fields, primarily within neuroscience, medicine, and biochemistry, genetics, and molecular biology. Sawa's work includes significant contributions to cognitive neuroscience, molecular biology, neurology, radiology, nuclear medicine, and imaging, as well as cellular and molecular neuroscience.

The main topics addressed in Sawa's research include:

  • Functional Brain Connectivity Studies
  • Advanced Neuroimaging Techniques and Applications
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Tryptophan and Brain Disorders
  • Schizophrenia Research and Treatment
  • Neural Dynamics and Brain Function
  • Olfactory and Sensory Function Studies

Sawa's publication record features papers in a variety of venues known for neuroscience and psychiatry-related research. Frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Molecular Psychiatry
  • Schizophrenia Research
  • Translational Psychiatry
  • Seminars in Cell and Developmental Biology

Among recent papers are:

  • "Improving polygenic prediction in ancestrally diverse populations," 2022, Nature Genetics
  • "Increased power by harmonizing structural MRI site differences with the ComBat batch adjustment method in ENIGMA," 2020, NeuroImage
  • "Towards a youth mental health paradigm: a perspective and roadmap," 2023, Molecular Psychiatry
  • "Association of Age, Antipsychotic Medication, and Symptom Severity in Schizophrenia With Proton Magnetic Resonance Spectroscopy Brain Glutamate Level," 2021, JAMA Psychiatry
  • "Prenatal immune stress blunts microglia reactivity, impairing neurocircuitry," 2022, Nature

Frequent collaborators working alongside Sawa include Kun Yang, Koko Ishizuka, Nicola G. Cascella, Jennifer M. Coughlin, and Andréia V. Faria. These collaborations reflect a diverse and multidisciplinary research network.

Awards related to Sawa's career include recognition as a Member of the Association of American Physicians.

Best Publications

  • Schizophrenia

    Unknown

  • S-nitrosylated GAPDH initiates apoptotic cell death by nuclear translocation following Siah1 binding

    Makoto R. Hara;Nishant Agrawal;Sangwon F. Kim;Matthew B. Cascio

  • Schizophrenia: diverse approaches to a complex disease.

    Akira Sawa;Solomon H. Snyder

  • Increased levels of glutamate in brains from patients with mood disorders.

    Kenji Hashimoto;Akira Sawa;Masaomi Iyo

  • A schizophrenia-associated mutation of DISC1 perturbs cerebral cortex development.

    Atsushi Kamiya;Atsushi Kamiya;Ken Ichiro Kubo;Toshifumi Tomoda;Toshifumi Tomoda;Manabu Takaki

  • Inducible expression of mutant α-synuclein decreases proteasome activity and increases sensitivity to mitochondria-dependent apoptosis

    Yuji Tanaka;Simone Engelender;Shuichi Igarashi;Raghuram K. Rao

  • Altering the course of schizophrenia: progress and perspectives

    Mark J. Millan;Annie Andrieux;George Bartzokis;Kristin Cadenhead

  • Linking neurodevelopmental and synaptic theories of mental illness through DISC1

    Nicholas J. Brandon;Akira Sawa

  • p53 mediates cellular dysfunction and behavioral abnormalities in Huntington's disease.

    Byoung Il Bae;Hong Xu;Shuichi Igarashi;Masahiro Fujimuro

  • Increased apoptosis of Huntington disease lymphoblasts associated with repeat length-dependent mitochondrial depolarization

    Akira Sawa;Gordon W. Wiegand;Jillian Cooper;Russell L. Margolis

  • Dominant-negative DISC1 transgenic mice display schizophrenia-associated phenotypes detected by measures translatable to humans

    Takatoshi Hikida;Hanna Jaaro-Peled;Saurav Seshadri;Kenichi Oishi

  • Disrupted-in-Schizophrenia 1 (DISC1) regulates spines of the glutamate synapse via Rac1

    Akiko Hayashi-Takagi;Manabu Takaki;Nick Graziane;Saurav Seshadri

  • The Insula: An Underestimated Brain Area in Clinical Neuroscience, Psychiatry, and Neurology

    Ho Namkung;Sun Hong Kim;Akira Sawa

  • Nitric oxide-induced nuclear GAPDH activates p300/CBP and mediates apoptosis

    Nilkantha Sen;Makoto R. Hara;Makoto R. Hara;Michael D. Kornberg;Matthew B. Cascio

  • KCTD13 is a major driver of mirrored neuroanatomical phenotypes of the 16p11.2 copy number variant.

    Christelle Golzio;Jason Willer;Michael E. Talkowski;Edwin C. Oh

  • Disrupted-in-Schizophrenia-1 (DISC-1): Mutant truncation prevents binding to NudE-like (NUDEL) and inhibits neurite outgrowth

    Yuji Ozeki;Toshifumi Tomoda;John Kleiderlein;Atsushi Kamiya

  • Endoplasmic reticulum stress and mitochondrial cell death pathways mediate A53T mutant alpha-synuclein-induced toxicity

    Wanli W. Smith;Haibing Jiang;Zhong Pei;Yuji Tanaka

  • Glyceraldehyde-3-Phosphate Dehydrogenase: Nuclear Translocation Participates in Neuronal and Nonneuronal Cell Death

    Akira Sawa;Adil A. Khan;Lynda D. Hester;Solomon H. Snyder

  • Dexras1: A G Protein Specifically Coupled to Neuronal Nitric Oxide Synthase via CAPON

    Ming Fang;Samie R. Jaffrey;Akira Sawa;Keqiang Ye

  • Neurodevelopmental mechanisms of schizophrenia: understanding disturbed postnatal brain maturation through neuregulin-1–ErbB4 and DISC1

    Hanna Jaaro-Peled;Akiko Hayashi-Takagi;Saurav Seshadri;Atsushi Kamiya

  • Knockdown of DISC1 by In Utero Gene Transfer Disturbs Postnatal Dopaminergic Maturation in the Frontal Cortex and Leads to Adult Behavioral Deficits

    Minae Niwa;Atsushi Kamiya;Rina Murai;Rina Murai;Ken ichiro Kubo

Frequent Co-Authors

Solomon H. Snyder
Solomon H. Snyder Johns Hopkins University School of Medicine
David J. Schretlen
David J. Schretlen Johns Hopkins University School of Medicine
Mikhail V. Pletnikov
Mikhail V. Pletnikov Johns Hopkins University
Nicholas J. Brandon
Nicholas J. Brandon Neumora Therapeutics Inc
Patricio O'Donnell
Patricio O'Donnell Alto Neuroscience
Jonathan Pevsner
Jonathan Pevsner National Institute of Mental Health
Richard L. Huganir
Richard L. Huganir Johns Hopkins University School of Medicine
Richard Anthony Edward Edden
Richard Anthony Edward Edden Johns Hopkins University School of Medicine
Noriaki Yahata
Noriaki Yahata National Institutes for Quantum and Radiological Science and Technology
Melvin G. McInnis
Melvin G. McInnis University of Michigan–Ann Arbor

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