What is he best known for?
The fields of study he is best known for:
- Gene
- Enzyme
- Internal medicine
His scientific interests lie mostly in Internal medicine, Endocrinology, Orexin, Neuroscience and Neuropeptide.
He usually deals with Internal medicine and limits it to topics linked to Non-rapid eye movement sleep and Sleep onset and Sleep Stages.
His Endocrinology research incorporates elements of Transgene, Neuropeptide Y receptor and Almorexant.
His Orexin research incorporates themes from Wakefulness, Energy homeostasis and Narcolepsy.
His research in Neuroscience intersects with topics in Glutamate receptor and Raphe nuclei.
Within one scientific family, Takeshi Sakurai focuses on topics pertaining to In situ hybridization under Neuropeptide, and may sometimes address concerns connected to G protein-coupled receptor.
His most cited work include:
- Orexins and Orexin Receptors: A Family of Hypothalamic Neuropeptides and G Protein-Coupled Receptors that Regulate Feeding Behavior (4455 citations)
- Cloning of a cDNA encoding a non-isopeptide-selective subtype of the endothelin receptor. (2244 citations)
- Genetic Ablation of Orexin Neurons in Mice Results in Narcolepsy, Hypophagia, and Obesity (1172 citations)
What are the main themes of his work throughout his whole career to date?
His main research concerns Internal medicine, Orexin, Endocrinology, Neuroscience and Wakefulness.
His study connects Cardiology and Internal medicine.
The Orexin study combines topics in areas such as Hypothalamus, Energy homeostasis and Narcolepsy.
His work investigates the relationship between Endocrinology and topics such as Receptor that intersect with problems in Molecular biology.
His study in Sleep in non-human animals, Arousal, GABAergic, Neuron and Excitatory postsynaptic potential is carried out as part of his studies in Neuroscience.
His research on Wakefulness often connects related areas such as Non-rapid eye movement sleep.
He most often published in these fields:
- Internal medicine (36.93%)
- Orexin (35.89%)
- Endocrinology (35.19%)
What were the highlights of his more recent work (between 2012-2021)?
- Neuroscience (27.70%)
- Orexin (35.89%)
- Endocrinology (35.19%)
In recent papers he was focusing on the following fields of study:
Takeshi Sakurai spends much of his time researching Neuroscience, Orexin, Endocrinology, Internal medicine and Wakefulness.
His work on Neuroscience deals in particular with GABAergic, Optogenetics, Sleep in non-human animals, Preoptic area and Inhibitory postsynaptic potential.
The study incorporates disciplines such as Lateral hypothalamus and Narcolepsy in addition to Orexin.
Takeshi Sakurai studied Endocrinology and Glutamate receptor that intersect with Prefrontal cortex.
All of his Internal medicine and Excitatory postsynaptic potential, Insulin resistance, Leptin, Metabolism and Carbohydrate metabolism investigations are sub-components of the entire Internal medicine study.
His study in Wakefulness is interdisciplinary in nature, drawing from both Hypothalamus, Locus coeruleus, Energy homeostasis and Non-rapid eye movement sleep.
Between 2012 and 2021, his most popular works were:
- The role of orexin in motivated behaviours (249 citations)
- Role of orexin in modulating arousal, feeding, and motivation (149 citations)
- Cellular clocks in AVP neurons of the SCN are critical for interneuronal coupling regulating circadian behavior rhythm. (124 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Enzyme
- Internal medicine
The scientist’s investigation covers issues in Orexin, Neuroscience, Internal medicine, Endocrinology and Wakefulness.
His studies deal with areas such as Hypothalamus, Lateral hypothalamus and Narcolepsy as well as Orexin.
When carried out as part of a general Internal medicine research project, his work on Receptor, Glutamate receptor, Circadian rhythm and Leptin is frequently linked to work in Sequestosome 1, therefore connecting diverse disciplines of study.
His work deals with themes such as Feeding behavior, Slice preparation, Arousal and Sensory system, which intersect with Wakefulness.
His Orexin receptor research focuses on subjects like Suvorexant, which are linked to Neuroscience of sleep.
Takeshi Sakurai combines subjects such as Autonomic nervous system and Energy homeostasis with his study of Orexin-A.
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