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Michihiro Mieda

Michihiro Mieda

D-Index & Metrics

Neuroscience

D-Index
40
Citations
7481
World Ranking
8037
National Ranking
275

Overview

Michihiro Mieda is affiliated with Kanazawa University in Japan and focuses on neuroscience and medicine with a particular emphasis on circadian rhythms, neuroendocrine regulation, and sleep-wakefulness research. Their work spans multiple interdisciplinary topics within physiology and cellular neuroscience.

Their research fields primarily include:

  • Neuroscience
  • Medicine

Subfields of study encompass:

  • Endocrine and Autonomic Systems
  • Physiology
  • Social Psychology
  • Cellular and Molecular Neuroscience
  • Cognitive Neuroscience

Key research topics addressed by Mieda are:

  • Circadian rhythm and melatonin
  • Neuroendocrine regulation and behavior
  • Sleep and Wakefulness Research
  • Photoreceptor and optogenetics research
  • Neuroscience of respiration and sleep
  • Dietary Effects on Health
  • Spaceflight effects on biology

Selected recent publications include:

  • "GABA from vasopressin neurons regulates the time at which suprachiasmatic nucleus molecular clocks enable circadian behavior," 2021, Proceedings of the National Academy of Sciences
  • "Brown adipocyte-specific knockout of Bmal1 causes mild but significant thermogenesis impairment in mice," 2021, Molecular Metabolism
  • "Vasopressin neurons in the paraventricular hypothalamus promote wakefulness via lateral hypothalamic orexin neurons," 2022, Current Biology
  • "The Circadian Clock, Nutritional Signals and Reproduction: A Close Relationship," 2023, International Journal of Molecular Sciences
  • "Time-Restricted Feeding Regulates Circadian Rhythm of Murine Uterine Clock," 2021, Current Developments in Nutrition

Frequent collaborators associated with Michihiro Mieda include:

  • Takashi Maejima
  • Yusuke Tsuno
  • Takiko Daikoku
  • Masanori Ono
  • Hiroshi Fujiwara

Common venues for Mieda's publications are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Proceedings of the National Academy of Sciences
  • Molecular Metabolism
  • Current Biology
  • International Journal of Molecular Sciences

Best Publications

  • Hypothalamic orexin neurons regulate arousal according to energy balance in mice.

    Akihiro Yamanaka;Carsten T. Beuckmann;Jon T. Willie;Junko Hara

  • Involvement of the Lateral Hypothalamic Peptide Orexin in Morphine Dependence and Withdrawal

    Dan Georgescu;Venetia Zachariou;Michel Barrot;Michel Barrot;Michihiro Mieda

  • Orexin peptides prevent cataplexy and improve wakefulness in an orexin neuron-ablated model of narcolepsy in mice

    Michihiro Mieda;Jon T. Willie;Junko Hara;Christopher M. Sinton

  • The dorsomedial hypothalamic nucleus as a putative food-entrainable circadian pacemaker

    Michihiro Mieda;S. Clay Williams;James A. Richardson;Kohichi Tanaka

  • Differential Roles of Orexin Receptor-1 and -2 in the Regulation of Non-REM and REM Sleep

    Michihiro Mieda;Emi Hasegawa;Yaz Y. Kisanuki;Yaz Y. Kisanuki;Christopher M. Sinton

  • Pharmacogenetic modulation of orexin neurons alters sleep/wakefulness states in mice.

    Koh Sasaki;Mika Suzuki;Michihiro Mieda;Natsuko Tsujino

  • Connectomics of orexin-producing neurons: interface of systems of emotion, energy homeostasis and arousal.

    Takeshi Sakurai;Michihiro Mieda

  • Cellular clocks in AVP neurons of the SCN are critical for interneuronal coupling regulating circadian behavior rhythm.

    Michihiro Mieda;Daisuke Ono;Emi Hasegawa;Hitoshi Okamoto

  • Astrocytes Regulate Daily Rhythms in the Suprachiasmatic Nucleus and Behavior

    Chak Foon Tso;Tatiana Simon;Alison C. Greenlaw;Tanvi Puri

  • Orexin Neurons Function in an Efferent Pathway of a Food-Entrainable Circadian Oscillator in Eliciting Food-Anticipatory Activity and Wakefulness

    Michihiro Mieda;S. Clay Williams;Christopher M. Sinton;James A. Richardson

  • The orexin system: roles in sleep/wake regulation

    Takeshi Sakurai;Michihiro Mieda;Natsuko Tsujino

  • Central control of bone remodeling by neuromedin U.

    Shingo Sato;Reiko Hanada;Ayako Kimura;Tomomi Abe

  • R-spondin3 is required for mouse placental development.

    Motoko Aoki;Michihiro Mieda;Toshio Ikeda;Yoshio Hamada

  • Orexin neurons suppress narcolepsy via 2 distinct efferent pathways

    Emi Hasegawa;Masashi Yanagisawa;Takeshi Sakurai;Michihiro Mieda

  • Indispensability of the glutamate transporters GLAST and GLT1 to brain development

    Toshiko R. Matsugami;Kentaro Tanemura;Michihiro Mieda;Reiko Nakatomi

  • Sleep, feeding, and neuropeptides: roles of orexins and orexin receptors.

    Michihiro Mieda;Masashi Yanagisawa

  • Orexin (hypocretin) receptor agonists and antagonists for treatment of sleep disorders. Rationale for development and current status.

    Michihiro Mieda;Takeshi Sakurai

  • Orexin Receptor-1 in the Locus Coeruleus Plays an Important Role in Cue-Dependent Fear Memory Consolidation

    Shingo Soya;Hirotaka Shoji;Emi Hasegawa;Mari Hondo

  • Disruption of Bmal1 Impairs Blood-Brain Barrier Integrity via Pericyte Dysfunction.

    Ryota Nakazato;Kenji Kawabe;Daisuke Yamada;Shinsuke Ikeno

  • Bone Resorption Is Regulated by Circadian Clock in Osteoblasts

    Takeshi Takarada;Cheng Xu;Hiroki Ochi;Ryota Nakazato

  • GABAergic neurons in the preoptic area send direct inhibitory projections to orexin neurons.

    Yuki C. Saito;Natsuko Tsujino;Emi Hasegawa;Kaori Akashi

Frequent Co-Authors

Jon T. Willie
Jon T. Willie Washington University in St. Louis
Tsuyoshi Miyakawa
Tsuyoshi Miyakawa Fujita Health University
Yuchio Yanagawa
Yuchio Yanagawa Gunma University
Kenji Sakimura
Kenji Sakimura Niigata University
Ken-ichi Honma
Ken-ichi Honma Hokkaido University
Sato Honma
Sato Honma Hokkaido University
Kohichi Tanaka
Kohichi Tanaka Tokyo Medical and Dental University
Stefan Herlitze
Stefan Herlitze Ruhr University Bochum
Michel Barrot
Michel Barrot Centre national de la recherche scientifique, CNRS

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