World's Best Scientists 2026 revealed!
Kenji Sakimura

Kenji Sakimura

D-Index & Metrics

Neuroscience

D-Index
91
Citations
27546
World Ranking
1075
National Ranking
16

Biology and Biochemistry

D-Index
91
Citations
27547
World Ranking
2339
National Ranking
143

Research.com Recognitions

  • 1958 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Kenji Sakimura is affiliated with Niigata University in Japan and has a substantial publication record in the fields of neuroscience and biochemistry, genetics, and molecular biology. Their work spans several subfields, including molecular biology, cellular and molecular neuroscience, cognitive neuroscience, neurology, and genetics.

The scientist's research themes cover a range of topics such as neuroscience and neuropharmacology, ion channel regulation and function, neurogenesis and neuroplasticity mechanisms, genetics and neurodevelopmental disorders, photoreceptor and optogenetics research, neuroendocrine regulation and behavior, as well as memory and neural mechanisms.

Kenji Sakimura has published multiple papers in well-recognized venues. Some recent notable papers include:

  • "p62/SQSTM1-droplet serves as a platform for autophagosome formation and anti-oxidative stress response" (2021, Nature Communications)
  • "A discrete neuronal circuit induces a hibernation-like state in rodents" (2020, Nature)
  • "Optimizing Nervous System-Specific Gene Targeting with Cre Driver Lines: Prevalence of Germline Recombination and Influencing Factors" (2020, Neuron)
  • "TDP-43 transports ribosomal protein mRNA to regulate axonal local translation in neuronal axons" (2020, Acta Neuropathologica)
  • "The UFM1 system regulates ER-phagy through the ufmylation of CYB5R3" (2022, Nature Communications)

Their frequent co-authors include Manabu Abe, Masahiko Watanabe, Rie Natsume, Keiichi Itoi, and Keizo Takao, suggesting ongoing collaborative research efforts.

Publication venues that regularly feature their work include bioRxiv (Cold Spring Harbor Laboratory), Scientific Reports, Cell Reports, Nature Communications, and the International Journal of Molecular Sciences.

In recognition of their contributions to science, Kenji Sakimura was awarded the status of Fellow of the American Association for the Advancement of Science (AAAS) in 1958.

Best Publications

  • Reduced hippocampal LTP and spatial learning in mice lacking NMDA receptor ε1 subunit

    Kenji Sakimura;Tatsuya Kutsuwada;Isao Ito;Toshiya Manabe

  • Impairment of suckling response, trigeminal neuronal pattern formation, and hippocampal LTD in NMDA receptor ε2 subunit mutant mice

    Tatsuya Kutsuwada;Kenji Sakimura;Toshiya Manabe;Chitoshi Takayama

  • The Endocannabinoid 2-Arachidonoylglycerol Produced by Diacylglycerol Lipase α Mediates Retrograde Suppression of Synaptic Transmission

    Asami Tanimura;Maya Yamazaki;Yuki Hashimotodani;Motokazu Uchigashima

  • Trans-synaptic interaction of GluRdelta2 and Neurexin through Cbln1 mediates synapse formation in the cerebellum.

    Takeshi Uemura;Sung-Jin Lee;Misato Yasumura;Tomonori Takeuchi

  • Distinct distributions of five N‐methyl‐D‐aspartate receptor channel subunit mRNAs in the forebrain

    Masahiko Watanabe;Y. Inoue;K. Sakimura;M. Mishina

  • Cloning and expression of the ε4 subunit of the NMDA receptor channel

    Kazutaka Ikeda;Michiaki Nagasawa;Hisashi Mori;Kazuaki Araki

  • Impaired Parallel Fiber→Purkinje Cell Synapse Stabilization during Cerebellar Development of Mutant Mice Lacking the Glutamate Receptor δ2 Subunit

    Hideo Kurihara;Kouichi Hashimoto;Masanobu Kano;Chitoshi Takayama

  • Selective scarcity of NMDA receptor channel subunits in the stratum lucidum (mossy fibre‐recipient layer) of the mouse hippocampal CA3 subfield

    Masahiko Watanabe;Masahiro Fukaya;Kenji Sakimura;Toshiya Manabe

  • Inverse Synaptic Tagging of Inactive Synapses via Dynamic Interaction of Arc/Arg3.1 with CaMKIIβ

    Hiroyuki Okuno;Kaori Akashi;Yuichiro Ishii;Nan Yagishita-Kyo

  • Increased Thresholds for Long-Term Potentiation and Contextual Learning in Mice Lacking the NMDA-type Glutamate Receptor ε1 Subunit

    Yuji Kiyama;Toshiya Manabe;Kenji Sakimura;Fumiko Kawakami

  • Distinct modes of AMPA receptor suppression at developing synapses by GluN2A and GluN2B: single-cell NMDA receptor subunit deletion in vivo.

    John A. Gray;Yun Shi;Hiroshi Usui;Matthew J. During

  • Forward-genetics analysis of sleep in randomly mutagenized mice

    Hiromasa Funato;Hiromasa Funato;Chika Miyoshi;Tomoyuki Fujiyama;Takeshi Kanda

  • Impairment of AMPA receptor function in cerebellar granule cells of ataxic mutant mouse stargazer.

    Kouichi Hashimoto;Masahiro Fukaya;Xiaoxi Qiao;Kenji Sakimura

  • Serine racemase is predominantly localized in neurons in mouse brain

    Kazushi Miya;Ran Inoue;Yoshimi Takata;Manabu Abe

  • p62/SQSTM1-droplet serves as a platform for autophagosome formation and anti-oxidative stress response

    Shun Kageyama;Sigurdur Runar Gudmundsson;Yu Shin Sou;Yoshinobu Ichimura

  • Rational Engineering of XCaMPs, a Multicolor GECI Suite for In Vivo Imaging of Complex Brain Circuit Dynamics

    Masatoshi Inoue;Masatoshi Inoue;Atsuya Takeuchi;Satoshi Manita;Shin-ichiro Horigane;Shin-ichiro Horigane

  • A discrete neuronal circuit induces a hibernation-like state in rodents

    Tohru M. Takahashi;Genshiro A. Sunagawa;Shingo Soya;Manabu Abe

  • Conditional gene targeting on the pure C57BL/6 genetic background.

    Masayoshi Mishina;Kenji Sakimura

  • Distal Extension of Climbing Fiber Territory and Multiple Innervation Caused by Aberrant Wiring to Adjacent Spiny Branchlets in Cerebellar Purkinje Cells Lacking Glutamate Receptor δ2

    Ryoichi Ichikawa;Taisuke Miyazaki;Masanobu Kano;Tsutomu Hashikawa

  • Targeting the SphK1/S1P/S1PR1 Axis That Links Obesity, Chronic Inflammation, and Breast Cancer Metastasis

    Masayuki Nagahashi;Akimitsu Yamada;Akimitsu Yamada;Eriko Katsuta;Eriko Katsuta;Tomoyoshi Aoyagi

  • Role of the Carboxy-Terminal Region of the GluRε2 Subunit in Synaptic Localization of the NMDA Receptor Channel

    Hisashi Mori;Toshiya Manabe;Masahiko Watanabe;Yasushi Satoh

Frequent Co-Authors

Manabu Abe
Manabu Abe Niigata University
Masahiko Watanabe
Masahiko Watanabe Hokkaido University
Masayoshi Mishina
Masayoshi Mishina Ritsumeikan University
Masanobu Kano
Masanobu Kano University of Tokyo
Kouichi Hashimoto
Kouichi Hashimoto Hiroshima University
Masahiro Fukaya
Masahiro Fukaya Kitasato University
Miwako Yamasaki
Miwako Yamasaki Hokkaido University
Yasuo Takahashi
Yasuo Takahashi Niigata University
Taisuke Miyazaki
Taisuke Miyazaki Hokkaido University
Yuchio Yanagawa
Yuchio Yanagawa Gunma University

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