Seiji Ito

Best Publications

• Alternative splicing of C-terminal tail of prostaglandin E receptor subtype EP3 determines G-protein specificity.

  Tsunehisa Namba;Yukihiko Sugimoto;Manabu Negishi;Atsushi Irie

  799
  Citations

• Identification and Characterization of a Novel Type of Membrane-Associated Prostaglandin E Synthase

  Naomi Tanikawa;Yoshihiro Ohmiya;Hiroaki Ohkubo;Katsuyuki Hashimoto

  378
  Citations

• Nocistatin, a peptide that blocks nociceptin action in pain transmission

  Emiko Okuda-Ashitaka;Toshiaki Minami;Shinro Tachibana;Yoshihiro Yoshihara;Yoshihiro Yoshihara

  335
  Citations

• Lack of tactile pain (allodynia) in lipocalin-type prostaglandin D synthase-deficient mice

  Naomi Eguchi;Toshiaki Minami;Naoki Shirafuji;Yoshihide Kanaoka

  333
  Citations

• Characterization of EP receptor subtypes responsible for prostaglandin E2-induced pain responses by use of EP1 and EP3 receptor knockout mice

  Toshiaki Minami;Hiroyuki Nakano;Takuya Kobayashi;Yukihiko Sugimoto

  271
  Citations

• Nociceptive effects induced by intrathecal administration of prostaglandin D2, E2, or F2α to conscious mice

  Rumiko Uda;Shigeko Horiguchi;Seiji Ito;Seiji Ito;Masayoshi Hyodo

  252
  Citations

• Fyn kinase‐mediated phosphorylation of NMDA receptor NR2B subunit at Tyr1472 is essential for maintenance of neuropathic pain

  Tetsuya Abe;Shinji Matsumura;Tayo Katano;Tamaki Mabuchi

  238
  Citations

• Close kinship of human 20alpha-hydroxysteroid dehydrogenase gene with three aldo-keto reductase genes.

  Mikio Nishizawa;Tatsuya Nakajima;Katsuhiko Yasuda;Hideharu Kanzaki

  213
  Citations

• Characterization of nociceptin hyperalgesia and allodynia in conscious mice.

  Naoki Hara;Toshiaki Minami;Emiko Okuda-Ashitaka;Tetsuo Sugimoto

  206
  Citations

• Molecular Cloning of the Human Histamine H1 Receptor Gene

  H. Fukui;K. Fujimoto;H. Mizuguchi;K. Sakamoto

  195
  Citations

• cDNA cloning, expression and characterization of human prostaglandin F synthase1

  Toshiko Suzuki-Yamamoto;Mikio Nishizawa;Motonari Fukui;Emiko Okuda-Ashitaka

  193
  Citations

• Prostaglandin D2: a biochemical perspective.

  S. Ito;Shuh Narumiya;O. Hayaishi

  180
  Citations

• Molecular cloning and expression of a cDNA of the bovine prostaglandin F2 alpha receptor.

  Sakamoto K;Ezashi T;Miwa K;Okuda-Ashitaka E

  175
  Citations

• Attenuation of neuropathic pain by the nociceptin/orphanin FQ antagonist JTC-801 is mediated by inhibition of nitric oxide production.

  Tamaki Mabuchi;Shinji Matsumura;Emiko Okuda-Ashitaka;Emiko Okuda-Ashitaka;Takahiro Kitano

  144
  Citations

• Purification and characterization of poly(ADP-ribose) synthetase from calf thymus.

  S Ito;Y Shizuta;O Hayaishi

  140
  Citations

• Prostaglandin E receptors in bovine adrenal medulla are coupled to adenylate cyclase via Gi and to phosphoinositide metabolism in a pertussis toxin-insensitive manner.

  M Negishi;S Ito;O Hayaishi

  140
  Citations

• Involvement of Rho-kinase in inflammatory and neuropathic pain through phosphorylation of myristoylated alanine-rich C-kinase substrate (MARCKS).

  S. Tatsumi;T. Mabuchi;T. Katano;S. Matsumura

  126
  Citations

• Involvement of primary afferent C-fibres in touch-evoked pain (allodynia) induced by prostaglandin E2.

  Toshiaki Minami;Emiko Okuda‐Ashitaka;Yuuichi Hori;Satoru Sakuma

  120
  Citations

• N-ethylmaleimide-sensitive fusion protein (NSF) is involved in central sensitization in the spinal cord through GluR2 subunit composition switch after inflammation.

  Tayo Katano;Hidemasa Furue;Emiko Okuda-Ashitaka;Mitsuo Tagaya

  119
  Citations

• Characterization of the glutamatergic system for induction and maintenance of allodynia.

  Toshiaki Minami;Shinji Matsumura;Emiko Okuda-Ashitaka;Keiko Shimamoto

  111
  Citations