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Medicine

D-Index
82
Citations
23776
World Ranking
16159
National Ranking
8129

Overview

Matthew D. Breyer is affiliated with Eli Lilly in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a focus on several subfields including Nephrology, Molecular Biology, Genetics, Endocrinology, Diabetes and Metabolism, and Pharmacology.

The scientist's main research topics involve Chronic Kidney Disease and Diabetes, Renal Diseases and Glomerulopathies, Diabetes Treatment and Management, Single-cell and spatial transcriptomics, Pancreatic function and diabetes, Diabetes and associated disorders, as well as Dialysis and Renal Disease Management.

Breyer's published papers include:

  • Mapping the single-cell transcriptomic response of murine diabetic kidney disease to therapies (2022), published in Cell Metabolism
  • Profibrotic Circulating Proteins and Risk of Early Progressive Renal Decline in Patients With Type 2 Diabetes With and Without Albuminuria (2020), published in Diabetes Care
  • Unbiased kidney-centric molecular categorization of chronic kidney disease as a step towards precision medicine (2024), published in Kidney International
  • Cyclooxygenase-2 contributes to diabetic nephropathy through glomerular EP4 receptor (2022), published in Prostaglandins & Other Lipid Mediators
  • The Use of Genomics to Drive Kidney Disease Drug Discovery and Development (2020), published in Clinical Journal of the American Society of Nephrology

Their work has appeared frequently in the Journal of the American Society of Nephrology, with 15 publications, in addition to contributions in Diabetes Care, Cell Metabolism, Kidney International, and Prostaglandins & Other Lipid Mediators.

Frequent co-authors in their research collaborations include:

  • Maria Chiara Magnone
  • Dermot F. Reilly
  • Kevin L. Duffin
  • Romer A. González-Villalobos
  • Viji Nair

Best Publications

  • Prostanoid receptors: subtypes and signaling.

    Richard M Breyer;Carey K Bagdassarian;Scott A Myers;Matthew D Breyer

  • Cyclooxygenase-2 is associated with the macula densa of rat kidney and increases with salt restriction.

    Raymond C. Harris;James A. McKanna;Yoichi Akai;Harry R. Jacobson

  • Mouse Models of Diabetic Nephropathy

    Frank C. Brosius;Charles E. Alpers;Erwin P. Bottinger;Matthew D. Breyer

  • Thiazolidinediones expand body fluid volume through PPARγ stimulation of ENaC-mediated renal salt absorption

    You Fei Guan;Chuanming Hao;Dae Ryong Cha;Reena Rao

  • Mesangial cell, glomerular and renal vascular responses to endothelin in the rat kidney. Elucidation of signal transduction pathways.

    K F Badr;J J Murray;M D Breyer;K Takahashi

  • Peroxisome proliferator-activated receptors (PPARs): Novel therapeutic targets in renal disease

    YouFei Guan;Matthew D. Breyer

  • SALT-SENSITIVE HYPERTENSION AND REDUCED FERTILITY IN MICE LACKING THE PROSTAGLANDIN EP2 RECEPTOR

    Christopher R.J. Kennedy;Yahua Zhang;Suzanne Brandon;Youfei Guan

  • Endothelial Nitric Oxide Synthase Deficiency Produces Accelerated Nephropathy in Diabetic Mice

    Hui John Zhao;Suwan Wang;Huifang Cheng;Ming-zhi Zhang

  • Serial determination of glomerular filtration rate in conscious mice using FITC-inulin clearance

    Zhonghua Qi;Zhonghua Qi;Irene Whitt;Amit Mehta;Jianping Jin

  • Physiological regulation of cyclooxygenase-2 in the kidney

    Raymond C. Harris;Matthew D. Breyer

  • Prostaglandin E receptors and the kidney

    Matthew D. Breyer;Richard M. Breyer

  • Sirt1 activation protects the mouse renal medulla from oxidative injury

    Wenjuan He;Yingying Wang;Ming-Zhi Zhang;Li You

  • Physiological Regulation of Prostaglandins in the Kidney

    Chuan-Ming Hao;Matthew D Breyer

  • Opposite effects of cyclooxygenase-1 and -2 activity on the pressor response to angiotensin II.

    Zhonghua Qi;Chuan-Ming Hao;Robert I. Langenbach;Richard M. Breyer

  • Characterization of Susceptibility of Inbred Mouse Strains to Diabetic Nephropathy

    Zhonghua Qi;Hiroki Fujita;Jianping Jin;Linda S. Davis

  • The next generation of therapeutics for chronic kidney disease

    Matthew D. Breyer;Katalin Susztak

  • G protein-coupled prostanoid receptors and the kidney.

    Matthew D Breyer;Richard M Breyer

  • Expression of peroxisome proliferator-activated receptors in urinary tract of rabbits and humans

    Youfei Guan;Yahua Zhang;Linda Davis;Matthew D. Breyer

  • Alterations in the regulation of androgen-sensitive Cyp 4a monooxygenases cause hypertension

    Vijaykumar R. Holla;Fadi Adas;John D. Imig;Xueying Zhao

  • Long-Term Treatment of Glucagon-Like Peptide-1 Analog Exendin-4 Ameliorates Diabetic Nephropathy through Improving Metabolic Anomalies in db/db Mice

    Cheol Whee Park;Hyeong Wook Kim;Seung Hyun Ko;Ji Hee Lim

Frequent Co-Authors

Richard M. Breyer
Richard M. Breyer Vanderbilt University Medical Center
Raymond C. Harris
Raymond C. Harris Vanderbilt University Medical Center
Agnes B. Fogo
Agnes B. Fogo Vanderbilt University Medical Center
Ambra Pozzi
Ambra Pozzi Vanderbilt University Medical Center
Min Zhao
Min Zhao University of the Sunshine Coast
Roy Zent
Roy Zent Vanderbilt University Medical Center
Andrzej S. Krolewski
Andrzej S. Krolewski Harvard University
Joseph V. Bonventre
Joseph V. Bonventre Brigham and Women's Hospital
Kumar Sharma
Kumar Sharma The University of Texas Health Science Center at San Antonio
Jorge H. Capdevila
Jorge H. Capdevila Vanderbilt University

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