Yuan Xiang Tao focuses on Neuropathic pain, Dorsal root ganglion, Hyperalgesia, Neuroscience and Pharmacology. His RNA research extends to Neuropathic pain, which is thematically connected. The study incorporates disciplines such as Nerve injury, Peripheral nerve injury, Antisense RNA, Cell biology and Regulation of gene expression in addition to Dorsal root ganglion.
His studies deal with areas such as Nitric oxide synthase, Opioid receptor, Opioid and Chronic pain as well as Hyperalgesia. His Neuroscience study combines topics in areas such as NMDA receptor, Glutamate receptor, Neurotransmission and Synaptic plasticity. His biological study spans a wide range of topics, including Anesthesia, Nociception, Inflammation, PI3K/AKT/mTOR pathway and Allodynia.
His primary scientific interests are in Neuropathic pain, Neuroscience, Pharmacology, Dorsal root ganglion and Spinal cord. The concepts of his Neuropathic pain study are interwoven with issues in Endocrinology, Nerve injury and Internal medicine, Sciatic nerve, Peripheral nerve injury. Yuan Xiang Tao has included themes like NMDA receptor, AMPA receptor, Glutamate receptor and Posterior Horn Cell in his Neuroscience study.
His Pharmacology research includes themes of Hyperalgesia, Nociception and Opioid. His work focuses on many connections between Dorsal root ganglion and other disciplines, such as Cell biology, that overlap with his field of interest in Neurotransmission. His Spinal cord research focuses on subjects like Anatomy, which are linked to Substance P.
The scientist’s investigation covers issues in Neuropathic pain, Dorsal root ganglion, Pharmacology, Downregulation and upregulation and Neuroscience. His research integrates issues of Endocrinology, Internal medicine, Sciatic nerve, Peripheral nerve injury and Spinal cord in his study of Neuropathic pain. Yuan Xiang Tao combines subjects such as Spinal nerve, Microinjection, EHMT2, Long non-coding RNA and Allodynia with his study of Dorsal root ganglion.
His research in Pharmacology tackles topics such as Hyperalgesia which are related to areas like Fentanyl and Prostaglandin E2. His Downregulation and upregulation research is multidisciplinary, relying on both Morphine, DNA methylation, Nociception, Analgesic and Apoptosis. His Neuroscience research focuses on Chronic pain in particular.
His main research concerns Neuropathic pain, Dorsal root ganglion, Pharmacology, Peripheral nerve injury and Microinjection. His Neuropathic pain study incorporates themes from Posttraumatic stress and DNA methylation. His Dorsal root ganglion study deals with the bigger picture of Neuroscience.
His work in Pharmacology tackles topics such as Downregulation and upregulation which are related to areas like Analgesic and Morphine. The various areas that he examines in his Peripheral nerve injury study include CAMP response element binding, Endocrinology and Gene expression. The Microinjection study which covers Sciatic nerve that intersects with Allodynia, Opioid, Octamer transcription factor and Signal transduction.
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A long noncoding RNA contributes to neuropathic pain by silencing Kcna2 in primary afferent neurons
Xiuli Zhao;Zongxiang Tang;Hongkang Zhang;Fidelis E. Atianjoh.
Nature Neuroscience (2013)
Impaired NMDA receptor-mediated postsynaptic function and blunted NMDA receptor-dependent persistent pain in mice lacking postsynaptic density-93 protein.
Yuan Xiang Tao;Gavin Rumbaugh;Guo Du Wang;Ronald S. Petralia.
The Journal of Neuroscience (2003)
Spinal glutamate uptake is critical for maintaining normal sensory transmission in rat spinal cord
Wen Jinn Liaw;Robert L. Stephens;Brian C. Binns;Yachun Chu;Yachun Chu.
Persistent Inflammation Induces GluR2 Internalization via NMDA Receptor-Triggered PKC Activation in Dorsal Horn Neurons
Jang Su Park;Nana Voitenko;Ronald S. Petralia;Xiaowei Guan.
The Journal of Neuroscience (2009)
Are voltage-gated sodium channels on the dorsal root ganglion involved in the development of neuropathic pain?
Wei-wei Wang;Jianguo G Gu;Yun-Qing Li;Yuan-Xiang Tao.
Molecular Pain (2011)
Evidence of neuronal excitatory amino acid carrier 1 expression in rat dorsal root ganglion neurons and their central terminals.
F Tao;W.-J Liaw;W.-J Liaw;B Zhang;M Yaster.
Opioid receptor–triggered spinal mTORC1 activation contributes to morphine tolerance and hyperalgesia
Ji Tian Xu;Ji Tian Xu;Jian Yuan Zhao;Xiuli Zhao;Davinna Ligons.
Journal of Clinical Investigation (2014)
Genetic knockout and pharmacologic inhibition of neuronal nitric oxide synthase attenuate nerve injury-induced mechanical hypersensitivity in mice.
Yun Guan;Myron Yaster;Srinivasa N. Raja;Yuan Xiang Tao.
Molecular Pain (2007)
Effect of genetic knockout or pharmacologic inhibition of neuronal nitric oxide synthase on complete Freund's adjuvant-induced persistent pain.
Ya Chun Chu;Yun Guan;John Skinner;Srinivasa N. Raja.
Peripherally acting mu-opioid receptor agonist attenuates neuropathic pain in rats after L5 spinal nerve injury.
Yun Guan;Lisa M. Johanek;Timothy V. Hartke;Beom Shim.
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