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Overview

Patrick M. Dougherty is affiliated with The University of Texas MD Anderson Cancer Center in the United States. Their primary field of study is Medicine, where they have contributed to various subfields including Physiology, Oncology, Psychiatry and Mental Health, Cellular and Molecular Neuroscience, and Neurology.

Their research work covers key topics such as Pain Mechanisms and Treatments, Cancer Treatment and Pharmacology, Cancer, Stress, Anesthesia, and Immune Response, Neuropeptides and Animal Physiology, Pain Management and Opioid Use, Botulinum Toxin and Related Neurological Disorders, and Multiple Myeloma Research and Treatments.

Selected recent publications by Patrick M. Dougherty include:

  • Loss of p53 drives neuron reprogramming in head and neck cancer, 2020, Nature
  • Spatial transcriptomics of dorsal root ganglia identifies molecular signatures of human nociceptors, 2022, Science Translational Medicine
  • Cancer-Associated Neurogenesis and Nerve-Cancer Cross-talk, 2020, Cancer Research
  • Studying human nociceptors: from fundamentals to clinic, 2021, Brain
  • RNA profiling of human dorsal root ganglia reveals sex differences in mechanisms promoting neuropathic pain, 2022, Brain

Frequent co-authors working alongside Dougherty include Theodore J. Price, Megan L. Uhelski, Yan Li, Claudio E. Tatsui, and Stephanie Shiers.

The venues where Patrick M. Dougherty publishes frequently include bioRxiv (Cold Spring Harbor Laboratory), Pain, Brain, Journal of Pain, and Nature.

Best Publications

  • Are the symptoms of cancer and cancer treatment due to a shared biologic mechanism? A cytokine-immunologic model of cancer symptoms

    Charles S. Cleeland;Gary J. Bennett;Robert Dantzer;Patrick M. Dougherty

  • Staining of glial fibrillary acidic protein (GFAP) in lumbar spinal cord increases following a sciatic nerve constriction injury.

    Chris Garrison;P. M. Dougherty;K. C. Kajander;S. M. Carlton

  • The role of NMDA and non-NMDA excitatory amino acid receptors in the excitation of primate spinothalamic tract neurons by mechanical, chemical, thermal, and electrical stimuli

    Patrick M Dougherty;J. Palecek;V. Paleckova;L. S. Sorkin

  • Spatial transcriptomics of dorsal root ganglia identifies molecular signatures of human nociceptors

    Unknown

  • Taxol-induced sensory disturbance is characterized by preferential impairment of myelinated fiber function in cancer patients.

    Patrick M. Dougherty;Juan P. Cata;Joseph V. Cordella;Allen Burton

  • An overview of animal models of pain: disease models and outcome measures.

    Nicholas S. Gregory;Amber L. Harris;Caleb R. Robinson;Patrick M. Dougherty

  • Loss of p53 drives neuron reprogramming in head and neck cancer.

    Moran Amit;Hideaki Takahashi;Hideaki Takahashi;Mihnea Paul Dragomir;Antje Lindemann

  • Enhancement of spinothalamic neuron responses to chemical and mechanical stimuli following combined micro-iontophoretic application of N-methyl-D-aspartic acid and substance P.

    P. M. Dougherty;W. D. Willis

  • A cytokine-based neuroimmunologic mechanism of cancer-related symptoms

    Bang-Ning Lee;Robert Dantzer;Keith E. Langley;Gary J. Bennett

  • Clinical and preclinical perspectives on Chemotherapy-Induced Peripheral Neuropathy (CIPN): a narrative review

    S. J.L. Flatters;Patrick M Dougherty;L. A. Colvin

  • Dorsal Root Ganglion Infiltration by Macrophages Contributes to Paclitaxel Chemotherapy-Induced Peripheral Neuropathy

    Hongmei Zhang;Yan Li;Marianna de Carvalho-Barbosa;Annemieke Kavelaars

  • Enhanced responses of spinothalamic tract neurons to excitatory amino acids accompany capsaicin-induced sensitization in the monkey.

    Patrick M Dougherty;W. D. Willis

  • Electrophysiological and transcriptomic correlates of neuropathic pain in human dorsal root ganglion neurons.

    Robert Y North;Yan Li;Pradipta Ray;Laurence D Rhines

  • Responses of spinothalamic tract cells to mechanical and thermal stimulation of skin in rats with experimental peripheral neuropathy.

    J. Palecek;V. Paleckova;Patrick M Dougherty;S. M. Carlton

  • Evidence that spinal astrocytes but not microglia contribute to the pathogenesis of Paclitaxel-induced painful neuropathy.

    Haijun Zhang;Seo Yeon Yoon;Hongmei Zhang;Patrick M. Dougherty

  • Pallidal activity during dystonia: somatosensory reorganisation and changes with severity.

    F. A. Lenz;J. I. Suarez;L. Verhagen Metman;S. G. Reich

  • Toll-like receptor 4 signaling contributes to Paclitaxel-induced peripheral neuropathy.

    Yan Li;Haijun Zhang;Hongmei Zhang;Alyssa K. Kosturakis

  • The Cancer Chemotherapeutic Paclitaxel Increases Human and Rodent Sensory Neuron Responses to TRPV1 by Activation of TLR4

    Yan Li;Pavel Adamek;Haijun Zhang;Claudio Esteves Tatsui

  • Cancer-Associated Neurogenesis and Nerve-Cancer Cross-talk.

    Deborah A. Silverman;Vena K. Martinez;Patrick M. Dougherty;Jeffrey N. Myers

  • DRG Voltage-Gated Sodium Channel 1.7 Is Upregulated in Paclitaxel-Induced Neuropathy in Rats and in Humans with Neuropathic Pain

    Yan Li;Robert Y. North;Laurence D. Rhines;Claudio Esteves Tatsui

  • Neural changes in acute arthritis in monkeys. I. Parallel enhancement of responses of spinothalamic tract neurons to mechanical stimulation and excitatory amino acids

    Patrick M Dougherty;K. A. Sluka;L. S. Sorkin;K. N. Westlund

  • Clinical and experimental findings in humans and animals with chemotherapy-induced peripheral neuropathy.

    Juan P Cata;H. R. Weng;B. N. Lee;J. M. Reuben

  • Central nervous system mechanisms of pain

    Frederick A. Lenz;Patrick M. Dougherty;Joel D. Greenspan;Arthur K. Asbury

Frequent Co-Authors

Frederick Lenz
Frederick Lenz Johns Hopkins University
Nachum Dafny
Nachum Dafny The University of Texas Health Science Center at Houston
Han-Rong Weng
Han-Rong Weng University of Georgia
Charles S. Cleeland
Charles S. Cleeland The University of Texas MD Anderson Cancer Center
Susan M. Carlton
Susan M. Carlton The University of Texas Medical Branch at Galveston
Theodore J. Price
Theodore J. Price The University of Texas at Dallas
Tito R. Mendoza
Tito R. Mendoza The University of Texas MD Anderson Cancer Center
William D. Willis
William D. Willis The University of Texas Medical Branch at Galveston
Richard H. Gracely
Richard H. Gracely University of North Carolina at Chapel Hill
Srinivasa N. Raja
Srinivasa N. Raja Johns Hopkins University

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