His primary scientific interests are in Neuroscience, Neuropathic pain, Pharmacology, Hyperalgesia and Anesthesia. His Neuroscience study frequently links to other fields, such as Nociceptor. He has researched Neuropathic pain in several fields, including Nerve injury and Spinal cord.
His Pharmacology research is multidisciplinary, relying on both Tyrosine kinase and Tyrosine, Tyrosine phosphorylation. His Hyperalgesia study combines topics in areas such as Inflammation, Chronic pain, Nitric oxide and Phosphorylation. His Anesthesia study combines topics in areas such as TRPV2, TRPV1, Mechanotransduction, Knockout mouse and Allodynia.
Yun Guan focuses on Neuroscience, Neuropathic pain, Stimulation, Anesthesia and Spinal cord. His Neuroscience research integrates issues from Gene expression and Epigenetics. Neuropathic pain is a subfield of Pharmacology that Yun Guan investigates.
His Pharmacology research is multidisciplinary, incorporating perspectives in Receptor, Hyperalgesia, Opioid and Nociception. Yun Guan has researched Anesthesia in several fields, including Persistent pain, Spinal cord stimulation and Allodynia. The concepts of his Spinal cord study are interwoven with issues in Internal medicine, Posterior Horn Cell, Spinal Cord Dorsal Horn and Endocrinology.
Yun Guan spends much of his time researching Endocrinology, Internal medicine, Neuroscience, Spinal cord and Dorsal root ganglion. His studies in Endocrinology integrate themes in fields like Therapeutic strategy and Sensory nerve. As part of his studies on Neuroscience, Yun Guan often connects relevant areas like Peripheral.
His work deals with themes such as Stimulation, Electrophysiology and Microglia, which intersect with Spinal cord. His work in Stimulation addresses issues such as Anesthesia, which are connected to fields such as Compound muscle action potential. He regularly ties together related areas like Neuropathic pain in his Dorsal root ganglion studies.
His primary areas of study are Neuropathic pain, Dorsal root ganglion, Internal medicine, Endocrinology and Opioid receptor. His work in Neuropathic pain covers topics such as Peripheral nervous system which are related to areas like Dermorphin, Stimulation, Gene expression, Bioinformatics and Nerve injury. To a larger extent, Yun Guan studies Neuroscience with the aim of understanding Stimulation.
Yun Guan has included themes like Spinal cord injury, Spinal cord and Sensory nerve in his Internal medicine study. His Endocrinology study incorporates themes from Neuroinflammation, Immune system and Neuroprotection. His research integrates issues of Analgesic, Pharmacology and Heteromer in his study of Opioid receptor.
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Sensory Neuron-Specific GPCR Mrgprs Are Itch Receptors Mediating Chloroquine-Induced Pruritus
Qin Liu;Zongxiang Tang;Lenka Surdenikova;Seungil Kim.
A subpopulation of nociceptors specifically linked to itch
Liang Han;Chao Ma;Qin Liu;Hao Jui Weng.
Nature Neuroscience (2013)
Tyrosine Phosphorylation of the NR2B Subunit of the NMDA Receptor in the Spinal Cord during the Development and Maintenance of Inflammatory Hyperalgesia
Wei Guo;Shiping Zou;Yun Guan;Tetsuya Ikeda.
The Journal of Neuroscience (2002)
Cannabinoids suppress inflammatory and neuropathic pain by targeting α3 glycine receptors
Wei Xiong;Tanxing Cui;Kejun Cheng;Fei Yang.
Journal of Experimental Medicine (2012)
TRP Vanilloid 2 Knock-Out Mice Are Susceptible to Perinatal Lethality But Display Normal Thermal and Mechanical Nociception
Una Park;Nisha Vastani;Yun Guan;Srinivasa N. Raja.
The Journal of Neuroscience (2011)
Spinal cord stimulation-induced analgesia: electrical stimulation of dorsal column and dorsal roots attenuates dorsal horn neuronal excitability in neuropathic rats
Yun Guan;Paul W. Wacnik;Fei Yang;Alene F. Carteret.
Parameters of Spinal Cord Stimulation and Their Role in Electrical Charge Delivery: A Review
Jonathan P. Miller;Sam Eldabe;Eric Buchser;Lisa M. Johanek.
Coupled Activation of Primary Sensory Neurons Contributes to Chronic Pain
Yu Shin Kim;Yu Shin Kim;Michael Anderson;Kyoungsook Park;Qin Zheng.
Changes in gene expression and neuronal phenotype in brain stem pain modulatory circuitry after inflammation.
Kenji Miki;Q. Q. Zhou;W. Guo;Y. Guan.
Journal of Neurophysiology (2002)
Spinal Cord Stimulation: Clinical Efficacy and Potential Mechanisms.
Andrei D. Sdrulla;Yun Guan;Srinivasa N. Raja.
Pain Practice (2018)
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