Yun Guan

Overview

Best Publications

• Sensory Neuron-Specific GPCR Mrgprs Are Itch Receptors Mediating Chloroquine-Induced Pruritus

  Qin Liu;Zongxiang Tang;Lenka Surdenikova;Seungil Kim

  882
  Citations

• A subpopulation of nociceptors specifically linked to itch

  Liang Han;Chao Ma;Qin Liu;Hao Jui Weng

  643
  Citations

• Injury-induced mechanical hypersensitivity requires C-low threshold mechanoreceptors

  Rebecca P. Seal;Xingmei Wang;Yabo Guan;Srinivasa N. Raja

  525
  Citations

• Subchondral bone osteoclasts induce sensory innervation and osteoarthritis pain

  Shouan Zhu;Jianxi Zhu;Jianxi Zhu;Gehua Zhen;Yihe Hu

  435
  Citations

• Spinal Cord Stimulation: Clinical Efficacy and Potential Mechanisms.

  Andrei D. Sdrulla;Yun Guan;Srinivasa N. Raja

  366
  Citations

• Cannabinoids suppress inflammatory and neuropathic pain by targeting α3 glycine receptors

  Wei Xiong;Tanxing Cui;Kejun Cheng;Fei Yang

  362
  Citations

• Coupled Activation of Primary Sensory Neurons Contributes to Chronic Pain

  Yu Shin Kim;Yu Shin Kim;Michael Anderson;Kyoungsook Park;Qin Zheng

  347
  Citations

• Tyrosine Phosphorylation of the NR2B Subunit of the NMDA Receptor in the Spinal Cord during the Development and Maintenance of Inflammatory Hyperalgesia

  Wei Guo;Shiping Zou;Yun Guan;Tetsuya Ikeda

  317
  Citations

• Prostaglandin E2 mediates sensory nerve regulation of bone homeostasis

  Hao Chen;Hao Chen;Bo Hu;Bo Hu;Xiao Lv;Shouan Zhu

  277
  Citations

• TRP Vanilloid 2 Knock-Out Mice Are Susceptible to Perinatal Lethality But Display Normal Thermal and Mechanical Nociception

  Una Park;Nisha Vastani;Yun Guan;Srinivasa N. Raja

  266
  Citations

• Parameters of Spinal Cord Stimulation and Their Role in Electrical Charge Delivery: A Review

  Jonathan P. Miller;Sam Eldabe;Eric Buchser;Lisa M. Johanek

  261
  Citations

• Spinal cord stimulation-induced analgesia: electrical stimulation of dorsal column and dorsal roots attenuates dorsal horn neuronal excitability in neuropathic rats

  Yun Guan;Paul W. Wacnik;Fei Yang;Alene F. Carteret

  212
  Citations

• Conventional and Kilohertz-frequency Spinal Cord Stimulation Produces Intensity- and Frequency-dependent Inhibition of Mechanical Hypersensitivity in a Rat Model of Neuropathic Pain

  Ronen Shechter;Fei Yang;Qian Xu;Yong Kwan Cheong

  199
  Citations

• Tmem100 is a regulator of TRPA1-TRPV1 complex and contributes to persistent pain

  Hao Jui Weng;Hao Jui Weng;Kush N. Patel;Nathaniel A. Jeske;Sonya M. Bierbower

  188
  Citations

• Changes in gene expression and neuronal phenotype in brain stem pain modulatory circuitry after inflammation.

  Kenji Miki;Q. Q. Zhou;W. Guo;Y. Guan

  175
  Citations

• Leaky Gate Model: Intensity-Dependent Coding of Pain and Itch in the Spinal Cord

  Shuohao Sun;Qian Xu;Changxiong Guo;Yun Guan

  163
  Citations

• Spinal Cord Stimulation: Neurophysiological and Neurochemical Mechanisms of Action

  Yun Guan

  155
  Citations

• Genetic knockout and pharmacologic inhibition of neuronal nitric oxide synthase attenuate nerve injury-induced mechanical hypersensitivity in mice.

  Yun Guan;Myron Yaster;Srinivasa N. Raja;Yuan Xiang Tao

  140
  Citations

• Effect of genetic knockout or pharmacologic inhibition of neuronal nitric oxide synthase on complete Freund's adjuvant-induced persistent pain.

  Ya Chun Chu;Yun Guan;John Skinner;Srinivasa N. Raja

  138
  Citations

• Peripherally acting mu-opioid receptor agonist attenuates neuropathic pain in rats after L5 spinal nerve injury.

  Yun Guan;Lisa M. Johanek;Timothy V. Hartke;Beom Shim

  134
  Citations

• Sensory innervation in porous endplates by Netrin-1 from osteoclasts mediates PGE2-induced spinal hypersensitivity in mice.

  Shuangfei Ni;Zemin Ling;Zemin Ling;Xiao Wang;Yong Cao;Yong Cao

  134
  Citations