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Research.com Recognitions

  • 2005 - Fellow of Alfred P. Sloan Foundation

Overview

Xinzhong Dong is a researcher affiliated with Johns Hopkins University School of Medicine in the United States. Their work is situated primarily within the field of Medicine, with significant contributions to several subfields including Physiology, Immunology, Molecular Biology, Dermatology, and Rheumatology.

The main topics addressed in their research portfolio focus on areas such as Dermatology and Skin Diseases, Pain Mechanisms and Treatments, Urticaria and Related Conditions, Ion Channels and Receptors, Mast Cells and Histamine, Asthma and Respiratory Diseases, and Allergic Rhinitis and Sensitization.

Xinzhong Dong has contributed to a number of recent scientific papers, including:

  • A basophil-neuronal axis promotes itch, 2021, Cell
  • Landscape of mast cell populations across organs in mice and humans, 2023, The Journal of Experimental Medicine
  • Synchronized cluster firing, a distinct form of sensory neuron activation, drives spontaneous pain, 2021, Neuron
  • Neural Mechanisms of Itch, 2020, Annual Review of Neuroscience
  • Prurigo Nodularis Is Characterized by Systemic and Cutaneous T Helper 22 Immune Polarization, 2021, Journal of Investigative Dermatology

The most frequent publication venues for their work include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Investigative Dermatology
  • Pain
  • eLife
  • Cell

Collaborations have involved several recurring coauthors, among them:

  • Nathachit Limjunyawong
  • Yun Guan
  • Brian Kim
  • Neil C. Ford
  • Xintong Dong

Throughout their career, Xinzhong Dong received recognition such as being named a Fellow of the Alfred P. Sloan Foundation in 2005.

Best Publications

  • Identification of a mast-cell-specific receptor crucial for pseudo-allergic drug reactions

    Benjamin D. McNeil;Priyanka Pundir;Sonya Meeker;Liang Han

  • Sensory Neuron-Specific GPCR Mrgprs Are Itch Receptors Mediating Chloroquine-Induced Pruritus

    Qin Liu;Zongxiang Tang;Lenka Surdenikova;Seungil Kim

  • A Diverse Family of GPCRs Expressed in Specific Subsets of Nociceptive Sensory Neurons

    Xinzhong Dong;Sang kyou Han;Mark J. Zylka;Melvin I. Simon

  • TRPA1 is required for histamine-independent, Mas-related G protein-coupled receptor-mediated itch

    Sarah R Wilson;Kristin A Gerhold;Amber Bifolck-Fisher;Qin Liu

  • Polyglutamine-Expanded Human Huntingtin Transgenes Induce Degeneration of Drosophila Photoreceptor Neurons

    George R Jackson;Iris Salecker;Xinzhong Dong;Xiang Yao

  • A subpopulation of nociceptors specifically linked to itch

    Liang Han;Chao Ma;Qin Liu;Hao Jui Weng

  • Subchondral bone osteoclasts induce sensory innervation and osteoarthritis pain

    Shouan Zhu;Jianxi Zhu;Jianxi Zhu;Gehua Zhen;Yihe Hu

  • A long noncoding RNA contributes to neuropathic pain by silencing Kcna2 in primary afferent neurons

    Xiuli Zhao;Zongxiang Tang;Hongkang Zhang;Fidelis E. Atianjoh

  • Central Terminal Sensitization of TRPV1 by Descending Serotonergic Facilitation Modulates Chronic Pain

    Yu Shin Kim;Yuxia Chu;Liang Han;Man Li;Man Li

  • Different activation signals induce distinct mast cell degranulation strategies

    Nicolas Gaudenzio;Riccardo Sibilano;Thomas Marichal;Philipp Starkl

  • Selective stimulation of astrocyte calcium in situ does not affect neuronal excitatory synaptic activity.

    Todd A. Fiacco;Cendra Agulhon;Sarah R. Taves;Jeremy Petravicz

  • A Mast-Cell-Specific Receptor Mediates Neurogenic Inflammation and Pain.

    Dustin P. Green;Nathachit Limjunyawong;Naina Gour;Priyanka Pundir

  • Peripheral and Central Mechanisms of Itch

    Xintong Dong;Xinzhong Dong

  • Mechanisms of Itch Evoked by β-Alanine

    Qin Liu;Parul Sikand;Chao Ma;Zongxiang Tang

  • Coupled Activation of Primary Sensory Neurons Contributes to Chronic Pain

    Yu Shin Kim;Yu Shin Kim;Michael Anderson;Kyoungsook Park;Qin Zheng

  • Activation of Mast-Cell-Expressed Mas-Related G-Protein-Coupled Receptors Drives Non-histaminergic Itch

    James Meixiong;Michael Anderson;Nathachit Limjunyawong;Mark F. Sabbagh

  • Sensory neurons and circuits mediating itch

    Robert H. LaMotte;Xinzhong Dong;Matthias Ringkamp

  • House dust mites activate nociceptor-mast cell clusters to drive type 2 skin inflammation.

    Nadine Serhan;Lilian Basso;Riccardo Sibilano;Camille Petitfils

  • Adult enteric nervous system in health is maintained by a dynamic balance between neuronal apoptosis and neurogenesis

    Subhash Kulkarni;Maria Adelaide Micci;Jenna Leser;Changsik Shin

  • Atypical expansion in mice of the sensory neuron-specific Mrg G protein-coupled receptor family

    Mark J. Zylka;Xinzhong Dong;Amber L. Southwell;David J. Anderson

  • Identification of a Mast-Cell-Specific Receptor Crucial for Pseudo-Allergic Drug Reactions

    Xinzhong Dong

Frequent Co-Authors

Yun Guan
Yun Guan Johns Hopkins University School of Medicine
Srinivasa N. Raja
Srinivasa N. Raja Johns Hopkins University
David J. Anderson
David J. Anderson California Institute of Technology
Bradley J. Undem
Bradley J. Undem Johns Hopkins University School of Medicine
Mei Wan
Mei Wan Johns Hopkins University School of Medicine
Stuart M. Brierley
Stuart M. Brierley Flinders University
Min Li
Min Li Chinese Academy of Sciences
Barbara S. Slusher
Barbara S. Slusher Johns Hopkins University School of Medicine
Robert H. LaMotte
Robert H. LaMotte Yale University
Solomon H. Snyder
Solomon H. Snyder Johns Hopkins University School of Medicine

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