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Stuart M. Brierley

Stuart M. Brierley

D-Index & Metrics

Neuroscience

D-Index
50
Citations
9500
World Ranking
5732
National Ranking
161

Overview

Stuart M. Brierley is affiliated with Flinders University in Australia and specializes in the field of Medicine, with a research focus spanning gastroenterology, physiology, sensory systems, molecular biology, and public health. Their work prominently addresses gastrointestinal motility and disorders, ion channels and receptors, pain mechanisms and treatments, endometriosis, diet and metabolism studies, urinary bladder and prostate research, and pregnancy-related medical research.

The scientist has contributed to several recent publications, including:

  • Pain in Endometriosis, 2020, Frontiers in Cellular Neuroscience
  • Gut enterochromaffin cells drive visceral pain and anxiety, 2023, Nature
  • Structure, Function, and Therapeutic Potential of the Trefoil Factor Family in the Gastrointestinal Tract, 2020, ACS Pharmacology & Translational Science
  • A spider-venom peptide with multitarget activity on sodium and calcium channels alleviates chronic visceral pain in a model of irritable bowel syndrome, 2020, Pain
  • Olorinab (APD371), a peripherally acting, highly selective, full agonist of the cannabinoid receptor 2, reduces colitis-induced acute and chronic visceral hypersensitivity in rodents, 2021, Pain

Frequent collaborators include Joel Castro, Andrea M. Harrington, Sonia Garcia-Caraballo, Gudrun Schober, and Luke Grundy. Stuart M. Brierley's research is regularly published in venues such as bioRxiv (Cold Spring Harbor Laboratory), Gastroenterology, Pain, Nature, and Journal of Neurochemistry.

Their scholarly output also includes book publications, notably "The Enteric Nervous System II" released by Springer Nature in 2022.

Major research themes in their work cover:

  • Gastrointestinal motility and disorders
  • Ion Channels and Receptors
  • Pain Mechanisms and Treatments
  • Endometriosis Research and Treatment
  • Diet and metabolism studies
  • Urinary Bladder and Prostate Research
  • Pregnancy-related medical research

Publication venues where Stuart M. Brierley frequently appears include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Gastroenterology
  • Pain
  • Nature
  • Journal of Neurochemistry

Best Publications

  • Enterochromaffin Cells Are Gut Chemosensors that Couple to Sensory Neural Pathways

    Nicholas W. Bellono;James R. Bayrer;Duncan B. Leitch;Joel Castro;Joel Castro

  • Splanchnic and pelvic mechanosensory afferents signal different qualities of colonic stimuli in mice

    Stuart M. Brierley;Stuart M. Brierley;R.Carter W. Jones;Gerald F. Gebhart;L.Ashley Blackshaw;L.Ashley Blackshaw

  • Different contributions of ASIC channels 1a, 2, and 3 in gastrointestinal mechanosensory function

    A J Page;S M Brierley;C M Martin;M P Price

  • Linaclotide inhibits colonic nociceptors and relieves abdominal pain via guanylate cyclase-C and extracellular cyclic guanosine 3',5'-monophosphate.

    Joel Castro;Joel Castro;Andrea M. Harrington;Andrea M. Harrington;Patrick A. Hughes;Patrick A. Hughes;Christopher M. Martin

  • Neuroplasticity and dysfunction after gastrointestinal inflammation

    Stuart M. Brierley;David R. Linden

  • The ion channel TRPA1 is required for normal mechanosensation and is modulated by algesic stimuli.

    Stuart M. Brierley;Stuart M. Brierley;Patrick A. Hughes;Patrick A. Hughes;Amanda J. Page;Amanda J. Page;Kelvin Y. Kwan

  • Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain.

    Jeremiah D. Osteen;Volker Herzig;John Gilchrist;Joshua J. Emrick

  • Selective Role for TRPV4 Ion Channels in Visceral Sensory Pathways

    Stuart M. Brierley;Amanda J. Page;Amanda J. Page;Patrick A. Hughes;Patrick A. Hughes;Birgit Adam

  • Sensory neuro-immune interactions differ between Irritable Bowel Syndrome subtypes

    Patrick A Hughes;Patrick A Hughes;Andrea M Harrington;Joel Castro;Tobias Liebregts;Tobias Liebregts

  • Expression of taste molecules in the upper gastrointestinal tract in humans with and without type 2 diabetes

    R L Young;K Sutherland;N Pezos;S M Brierley

  • Pain in Endometriosis

    Jessica Maddern;Luke Grundy;Joel Castro;Stuart M. Brierley;Stuart M. Brierley

  • Small bowel homing T cells are associated with symptoms and delayed gastric emptying in functional dyspepsia

    Tobias Liebregts;Birgit Adam;Christoph Bredack;Montri Gururatsakul

  • Post-inflammatory colonic afferent sensitisation: different subtypes, different pathways and different time courses.

    P A Hughes;S M Brierley;C M Martin;S J H Brookes

  • The ion channel ASIC1 contributes to visceral but not cutaneous mechanoreceptor function

    Amanda J. Page;Amanda J. Page;Stuart M. Brierley;Stuart M. Brierley;Christopher M. Martin;Christopher M. Martin;Carlos Martinez-Salgado

  • A novel role for TRPM8 in visceral afferent function

    Andrea M. Harrington;Andrea M. Harrington;Patrick A. Hughes;Patrick A. Hughes;Christopher M. Martin;Jing Yang;Jing Yang

  • Protease-activated receptor-2 in endosomes signals persistent pain of irritable bowel syndrome

    Nestor N. Jimenez-Vargas;Luke A. Pattison;Peishen Zhao;Tina Marie Lieu

  • Differential chemosensory function and receptor expression of splanchnic and pelvic colonic afferents in mice

    Stuart M. Brierley;R. Carter;W. Jones;Linjing Xu

  • TRPA1 contributes to specific mechanically activated currents and sensory neuron mechanical hypersensitivity

    Stuart M. Brierley;Stuart M. Brierley;Joel Castro;Andrea M. Harrington;Patrick A. Hughes

  • Transient receptor potential vanilloid 4 mediates protease activated receptor 2-induced sensitization of colonic afferent nerves and visceral hyperalgesia

    Walter E. B. Sipe;Stuart M. Brierley;Stuart M. Brierley;Christopher M. Martin;Benjamin D. Phillis

  • Gut enterochromaffin cells drive visceral pain and anxiety

    Unknown

  • Linaclotide Inhibits Colonic Nociceptors and Relieves Abdominal Pain via Guanylate Cyclase-C and Extracellular Cyclic Guanosine

    Joel Castro;Andrea M. Harrington;Patrick A. Hughes;Christopher M. Martin

Frequent Co-Authors

David J. Adams
David J. Adams Wellcome Sanger Institute
Nick J. Spencer
Nick J. Spencer Flinders University
John A. Wemmie
John A. Wemmie University of Iowa
Simon J.H. Brookes
Simon J.H. Brookes Flinders University
David Julius
David Julius University of California, San Francisco
Xinzhong Dong
Xinzhong Dong Johns Hopkins University School of Medicine
Gerald F. Gebhart
Gerald F. Gebhart University of Pittsburgh
Allan I. Basbaum
Allan I. Basbaum University of California, San Francisco
Glen C. Ulett
Glen C. Ulett Griffith University
Stephen G. Waxman
Stephen G. Waxman Yale University

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