Luis de Lecea

Overview

Best Publications

• The hypocretins: Hypothalamus-specific peptides with neuroexcitatory activity

  L. de Lecea;T. S. Kilduff;C. Peyron;X.-B. Gao

  4515
  Citations

• Neurons Containing Hypocretin (Orexin) Project to Multiple Neuronal Systems

  Christelle Peyron;Devin K. Tighe;Anthony N. van den Pol;Anthony N. van den Pol;Luis de Lecea

  4054
  Citations

• Neural substrates of awakening probed with optogenetic control of hypocretin neurons

  Antoine Roger Adamantidis;Feng Zhang;Alexander M Aravanis;Karl Deisseroth

  1544
  Citations

• Phasic Firing in Dopaminergic Neurons Is Sufficient for Behavioral Conditioning

  Hsing-Chen Tsai;Feng Zhang;Antoine Roger Adamantidis;Garret D Stuber

  1518
  Citations

• Tuning arousal with optogenetic modulation of locus coeruleus neurons.

  Matthew E Carter;Ofer Yizhar;Sachiko Chikahisa;Sachiko Chikahisa;Hieu Nguyen

  1097
  Citations

• Hypocretin/Orexin- and melanin-concentrating hormone-expressing cells form distinct populations in the rodent lateral hypothalamus: Relationship to the neuropeptide Y and agouti gene-related protein systems

  C. Broberger;L. De Lecea;J.G. Sutcliffe;T. Hökfelt

  1014
  Citations

• Optogenetic interrogation of neural circuits: technology for probing mammalian brain structures.

  Feng Zhang;Viviana Gradinaru;Antoine Roger Adamantidis;Remy Durand

  905
  Citations

• A novel adenylyl cyclase-activating serotonin receptor (5-HT7) implicated in the regulation of mammalian circadian rhythms.

  Timothy W. Lovenberg;Bruce M. Baron;Luis de Lecea;Joseph D. Miller

  846
  Citations

• Circuit-Breakers: Optical Technologies For Probing Neural Signals And Systems

  Feng Zhang;Alexander M. Aravanis;Antoine Adamantidis;Luis de Lecea

  786
  Citations

• Regional and cellular patterns of reelin mRNA expression in the forebrain of the developing and adult mouse

  Soledad Alcántara;Soledad Alcántara;Mónica Ruiz;Gabriella D’Arcangelo;Frederic Ezan

  638
  Citations

• Hypocretin-1 modulates rapid eye movement sleep through activation of locus coeruleus neurons.

  Patrice Bourgin;Salvador Huitrón-Reséndiz;Avron D. Spier;Véronique Fabre

  615
  Citations

• Role for hypocretin in mediating stress-induced reinstatement of cocaine-seeking behavior.

  Benjamin Boutrel;Paul J. Kenny;Sheila E. Specio;Rémi Martin-Fardon

  613
  Citations

• Neuropeptide S: A Neuropeptide Promoting Arousal and Anxiolytic-like Effects

  Yan Ling Xu;Rainer K. Reinscheid;Salvador Huitron-Resendiz;Stewart D. Clark

  579
  Citations

• VTA dopaminergic neurons regulate ethologically relevant sleep–wake behaviors

  Ada Eban-Rothschild;Gideon Rothschild;William J Giardino;Jeff R Jones

  567
  Citations

• The hypocretins: setting the arousal threshold.

  J. Gregor Sutcliffe;Luis de Lecea

  529
  Citations

• Interaction between the Corticotropin-Releasing Factor System and Hypocretins (Orexins): A Novel Circuit Mediating Stress Response

  Raphaëlle Winsky-Sommerer;Akihiro Yamanaka;Sabrina Diano;Erzsebet Borok

  511
  Citations

• A cortical neuropeptide with neuronal depressant and sleep-modulating properties

  Luis de Lecea;José R. Criado;Óscar Prospero-Garcia;Kaare M. Gautvik

  491
  Citations

• Optogenetic interrogation of dopaminergic modulation of the multiple phases of reward-seeking behavior.

  Antoine Roger Adamantidis;Hsing-Chen Tsai;Benjamin Boutrel;Feng Zhang

  450
  Citations

• Transgenic mice with a reduced core body temperature have an increased life span

  Bruno Conti;Manuel Sanchez-Alavez;Raphaelle Winsky-Sommerer;Maria Concetta Morale

  443
  Citations

• Overview of the most prevalent hypothalamus-specific mRNAs, as identified by directional tag PCR subtraction

  Gautvik Km;de Lecea L;Gautvik Vt;Danielson Pe

  334
  Citations

• The hypocretins: excitatory neuromodulatory peptides for multiple homeostatic systems, including sleep and feeding.

  J. Gregor Sutcliffe;Luis de Lecea

  301
  Citations

• The hypocretins/orexins: integrators of multiple physiological functions

  Jingcheng Li;Zhian Hu;Luis de Lecea

  298
  Citations

• Cortistatin: a member of the somatostatin neuropeptide family with distinct physiological functions.

  Avron D Spier;Luis de Lecea

  277
  Citations