D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Neuroscience D-index 65 Citations 21,850 148 World Ranking 1134 National Ranking 579

Overview

What is he best known for?

The fields of study he is best known for:

  • Neuroscience
  • Gene
  • Internal medicine

Luis de Lecea mainly focuses on Neuroscience, Optogenetics, Neuropeptide, Lateral hypothalamus and Wakefulness. His biological study spans a wide range of topics, including Endocrinology and Internal medicine. The Optogenetics study combines topics in areas such as Biological neural network and Dopaminergic, Dopamine, Ventral tegmental area.

His Neuropeptide study combines topics in areas such as Dentate gyrus, Self-administration, Parvalbumin and Somatostatin. His studies in Lateral hypothalamus integrate themes in fields like Parabrachial area and Raphe nuclei. His research in Wakefulness intersects with topics in Rapid eye movement sleep, Locus coeruleus and Photostimulation.

His most cited work include:

  • Neurons Containing Hypocretin (Orexin) Project to Multiple Neuronal Systems (2792 citations)
  • Phasic Firing in Dopaminergic Neurons Is Sufficient for Behavioral Conditioning (954 citations)
  • Neural substrates of awakening probed with optogenetic control of hypocretin neurons (941 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of investigation include Neuroscience, Neuropeptide, Arousal, Endocrinology and Internal medicine. Many of his studies on Neuroscience involve topics that are commonly interrelated, such as Orexin. Within one scientific family, he focuses on topics pertaining to Somatostatin under Neuropeptide, and may sometimes address concerns connected to Hippocampal formation.

As a member of one scientific family, Luis de Lecea mostly works in the field of Arousal, focusing on Sleep in non-human animals and, on occasion, Circadian rhythm. In the subject of general Endocrinology, his work in Ghrelin, Cholinergic and Acetylcholine is often linked to Leptin, thereby combining diverse domains of study. Luis de Lecea works mostly in the field of Wakefulness, limiting it down to concerns involving Narcolepsy and, occasionally, Orexin receptor.

He most often published in these fields:

  • Neuroscience (69.43%)
  • Neuropeptide (29.02%)
  • Arousal (26.94%)

What were the highlights of his more recent work (between 2017-2021)?

  • Neuroscience (69.43%)
  • Arousal (26.94%)
  • Optogenetics (23.83%)

In recent papers he was focusing on the following fields of study:

Luis de Lecea spends much of his time researching Neuroscience, Arousal, Optogenetics, Sleep in non-human animals and Wakefulness. His Neuroscience study incorporates themes from Neuropeptide and Orexin. His Arousal research is multidisciplinary, relying on both Addiction, Vigilance, Hypocretin orexin and Anxiety.

His Optogenetics study which covers Stimulation that intersects with Gene knockdown, Lateral parabrachial nucleus and Gene silencing. His research investigates the link between Wakefulness and topics such as Sleep wake that cross with problems in Neuronal circuits. Luis de Lecea has included themes like GABAergic and Immune system in his Lateral hypothalamus study.

Between 2017 and 2021, his most popular works were:

  • Parallel circuits from the bed nuclei of stria terminalis to the lateral hypothalamus drive opposing emotional states. (77 citations)
  • Neuronal Mechanisms for Sleep/Wake Regulation and Modulatory Drive (66 citations)
  • In vivo cell type-specific CRISPR knockdown of dopamine beta hydroxylase reduces locus coeruleus evoked wakefulness. (43 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Neuroscience
  • Neuron

His scientific interests lie mostly in Neuroscience, Orexin, Wakefulness, Optogenetics and Arousal. Luis de Lecea mostly deals with Neuronal circuits in his studies of Neuroscience. The study incorporates disciplines such as GABAergic, Extended amygdala, Stria terminalis and Lateral hypothalamus in addition to Orexin.

His Wakefulness research incorporates themes from Sleep wake, Circadian rhythm and Stimulation. His research integrates issues of Analysis of variance, Endocrinology, Extinction and Addiction, Craving in his study of Arousal. His Neuropeptide study integrates concerns from other disciplines, such as Hypothalamus, Biological neural network and Nerve net.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Neurons Containing Hypocretin (Orexin) Project to Multiple Neuronal Systems

Christelle Peyron;Devin K. Tighe;Anthony N. van den Pol;Anthony N. van den Pol;Luis de Lecea.
The Journal of Neuroscience (1998)

3464 Citations

Neural substrates of awakening probed with optogenetic control of hypocretin neurons

Antoine Roger Adamantidis;Feng Zhang;Alexander M Aravanis;Karl Deisseroth.
Nature (2007)

1253 Citations

Phasic Firing in Dopaminergic Neurons Is Sufficient for Behavioral Conditioning

Hsing-Chen Tsai;Feng Zhang;Antoine Roger Adamantidis;Garret D Stuber.
Science (2009)

1207 Citations

A novel adenylyl cyclase-activating serotonin receptor (5-HT7) implicated in the regulation of mammalian circadian rhythms.

Timothy W. Lovenberg;Bruce M. Baron;Luis de Lecea;Joseph D. Miller.
Neuron (1993)

799 Citations

Optogenetic interrogation of neural circuits: technology for probing mammalian brain structures.

Feng Zhang;Viviana Gradinaru;Antoine Roger Adamantidis;Remy Durand.
Nature Protocols (2010)

771 Citations

Circuit-Breakers: Optical Technologies For Probing Neural Signals And Systems

Feng Zhang;Alexander M. Aravanis;Antoine Adamantidis;Luis de Lecea.
(2007)

725 Citations

Tuning arousal with optogenetic modulation of locus coeruleus neurons.

Matthew E Carter;Ofer Yizhar;Sachiko Chikahisa;Sachiko Chikahisa;Hieu Nguyen.
Nature Neuroscience (2010)

685 Citations

Regional and cellular patterns of reelin mRNA expression in the forebrain of the developing and adult mouse

Soledad Alcántara;Soledad Alcántara;Mónica Ruiz;Gabriella D’Arcangelo;Frederic Ezan.
The Journal of Neuroscience (1998)

583 Citations

Hypocretin-1 modulates rapid eye movement sleep through activation of locus coeruleus neurons.

Patrice Bourgin;Salvador Huitrón-Reséndiz;Avron D. Spier;Véronique Fabre.
The Journal of Neuroscience (2000)

565 Citations

Role for hypocretin in mediating stress-induced reinstatement of cocaine-seeking behavior.

Benjamin Boutrel;Paul J. Kenny;Sheila E. Specio;Rémi Martin-Fardon.
Proceedings of the National Academy of Sciences of the United States of America (2005)

532 Citations

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