Luis de Lecea mainly focuses on Neuroscience, Optogenetics, Neuropeptide, Lateral hypothalamus and Wakefulness. His biological study spans a wide range of topics, including Endocrinology and Internal medicine. The Optogenetics study combines topics in areas such as Biological neural network and Dopaminergic, Dopamine, Ventral tegmental area.
His Neuropeptide study combines topics in areas such as Dentate gyrus, Self-administration, Parvalbumin and Somatostatin. His studies in Lateral hypothalamus integrate themes in fields like Parabrachial area and Raphe nuclei. His research in Wakefulness intersects with topics in Rapid eye movement sleep, Locus coeruleus and Photostimulation.
His primary areas of investigation include Neuroscience, Neuropeptide, Arousal, Endocrinology and Internal medicine. Many of his studies on Neuroscience involve topics that are commonly interrelated, such as Orexin. Within one scientific family, he focuses on topics pertaining to Somatostatin under Neuropeptide, and may sometimes address concerns connected to Hippocampal formation.
As a member of one scientific family, Luis de Lecea mostly works in the field of Arousal, focusing on Sleep in non-human animals and, on occasion, Circadian rhythm. In the subject of general Endocrinology, his work in Ghrelin, Cholinergic and Acetylcholine is often linked to Leptin, thereby combining diverse domains of study. Luis de Lecea works mostly in the field of Wakefulness, limiting it down to concerns involving Narcolepsy and, occasionally, Orexin receptor.
Luis de Lecea spends much of his time researching Neuroscience, Arousal, Optogenetics, Sleep in non-human animals and Wakefulness. His Neuroscience study incorporates themes from Neuropeptide and Orexin. His Arousal research is multidisciplinary, relying on both Addiction, Vigilance, Hypocretin orexin and Anxiety.
His Optogenetics study which covers Stimulation that intersects with Gene knockdown, Lateral parabrachial nucleus and Gene silencing. His research investigates the link between Wakefulness and topics such as Sleep wake that cross with problems in Neuronal circuits. Luis de Lecea has included themes like GABAergic and Immune system in his Lateral hypothalamus study.
His scientific interests lie mostly in Neuroscience, Orexin, Wakefulness, Optogenetics and Arousal. Luis de Lecea mostly deals with Neuronal circuits in his studies of Neuroscience. The study incorporates disciplines such as GABAergic, Extended amygdala, Stria terminalis and Lateral hypothalamus in addition to Orexin.
His Wakefulness research incorporates themes from Sleep wake, Circadian rhythm and Stimulation. His research integrates issues of Analysis of variance, Endocrinology, Extinction and Addiction, Craving in his study of Arousal. His Neuropeptide study integrates concerns from other disciplines, such as Hypothalamus, Biological neural network and Nerve net.
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Neurons Containing Hypocretin (Orexin) Project to Multiple Neuronal Systems
Christelle Peyron;Devin K. Tighe;Anthony N. van den Pol;Anthony N. van den Pol;Luis de Lecea.
The Journal of Neuroscience (1998)
Neural substrates of awakening probed with optogenetic control of hypocretin neurons
Antoine Roger Adamantidis;Feng Zhang;Alexander M Aravanis;Karl Deisseroth.
Phasic Firing in Dopaminergic Neurons Is Sufficient for Behavioral Conditioning
Hsing-Chen Tsai;Feng Zhang;Antoine Roger Adamantidis;Garret D Stuber.
A novel adenylyl cyclase-activating serotonin receptor (5-HT7) implicated in the regulation of mammalian circadian rhythms.
Timothy W. Lovenberg;Bruce M. Baron;Luis de Lecea;Joseph D. Miller.
Optogenetic interrogation of neural circuits: technology for probing mammalian brain structures.
Feng Zhang;Viviana Gradinaru;Antoine Roger Adamantidis;Remy Durand.
Nature Protocols (2010)
Circuit-Breakers: Optical Technologies For Probing Neural Signals And Systems
Feng Zhang;Alexander M. Aravanis;Antoine Adamantidis;Luis de Lecea.
Tuning arousal with optogenetic modulation of locus coeruleus neurons.
Matthew E Carter;Ofer Yizhar;Sachiko Chikahisa;Sachiko Chikahisa;Hieu Nguyen.
Nature Neuroscience (2010)
Regional and cellular patterns of reelin mRNA expression in the forebrain of the developing and adult mouse
Soledad Alcántara;Soledad Alcántara;Mónica Ruiz;Gabriella D’Arcangelo;Frederic Ezan.
The Journal of Neuroscience (1998)
Hypocretin-1 modulates rapid eye movement sleep through activation of locus coeruleus neurons.
Patrice Bourgin;Salvador Huitrón-Reséndiz;Avron D. Spier;Véronique Fabre.
The Journal of Neuroscience (2000)
Role for hypocretin in mediating stress-induced reinstatement of cocaine-seeking behavior.
Benjamin Boutrel;Paul J. Kenny;Sheila E. Specio;Rémi Martin-Fardon.
Proceedings of the National Academy of Sciences of the United States of America (2005)
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