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Medicine

D-Index
92
Citations
29301
World Ranking
11366
National Ranking
5825

Overview

Kenneth B. Margulies is affiliated with the University of Pennsylvania in the United States. Their research work primarily spans the fields of medicine and biochemistry, genetics, and molecular biology.

Their subfields of study include cardiology and cardiovascular medicine, molecular biology, surgery, physiology, and biomedical engineering.

Main topics covered in their research involve cardiovascular function and risk factors, cardiomyopathy and myosin studies, heart failure treatment and management, diet and metabolism studies, cardiac structural anomalies and repair, RNA modifications and cancer, as well as cardiac fibrosis and remodeling.

The scientist has published in several frequent venues, notably:

  • Circulation
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Circulation Research
  • Journal of the American College of Cardiology
  • JACC Basic to Translational Science

Recent papers authored by or including Kenneth B. Margulies are:

  • Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure, 2020, Nature Communications
  • Transcriptional and Cellular Diversity of the Human Heart, 2020, Circulation
  • Clinical Phenogroups in Heart Failure With Preserved Ejection Fraction, 2020, JACC Heart Failure
  • Single-nucleus profiling of human dilated and hypertrophic cardiomyopathy, 2022, Nature
  • Heart Failure With Recovered Left Ventricular Ejection Fraction, 2020, Journal of the American College of Cardiology

Frequent co-authors collaborating with Kenneth B. Margulies include:

  • Kenneth Bedi
  • Zoltàn Arany
  • Thomas P. Cappola
  • Benjamin L. Prosser
  • Michael P. Morley

Best Publications

  • Multi-Ethnic Genome-wide Association Study for Atrial Fibrillation

    Carolina Roselli;Mark D. Chaffin;Lu Chen Weng;Lu Chen Weng;Stefanie Aeschbacher

  • Evidence for Intramyocardial Disruption of Lipid Metabolism and Increased Myocardial Ketone Utilization in Advanced Human Heart Failure

    Kenneth C. Bedi;Nathaniel W. Snyder;Jeffrey Brandimarto;Moez Aziz

  • Cellular Basis of Abnormal Calcium Transients of Failing Human Ventricular Myocytes

    Valentino Piacentino;Christopher R. Weber;Xiongwen Chen;Jutta Weisser-Thomas

  • Effects of Liraglutide on Clinical Stability Among Patients With Advanced Heart Failure and Reduced Ejection Fraction: A Randomized Clinical Trial

    Kenneth B Margulies;Adrian F Hernandez;Margaret M Redfield;Michael M Givertz

  • Targeting cardiac fibrosis with engineered T cells.

    Haig Aghajanian;Toru Kimura;Joel G. Rurik;Aidan S. Hancock

  • Myocyte Recovery After Mechanical Circulatory Support in Humans With End-Stage Heart Failure

    Konstantina Dipla;Julian A. Mattiello;Valluvan Jeevanandam;Steven R. Houser

  • Low-dose dopamine or low-dose nesiritide in acute heart failure with renal dysfunction: the ROSE acute heart failure randomized trial.

    Horng H. Chen;Kevin J. Anstrom;Michael M. Givertz;Lynne W. Stevenson

  • A Microfabricated Platform to Measure and Manipulate the Mechanics of Engineered Cardiac Microtissues

    Thomas Boudou;Wesley R. Legant;Anbin Mu;Michael A. Borochin

  • Animal Models of Heart Failure A Scientific Statement From the American Heart Association

    Steven R. Houser;Kenneth B. Margulies;Anne M. Murphy;Francis G. Spinale

  • Cardiac Improvement During Mechanical Circulatory Support A Prospective Multicenter Study of the LVAD Working Group

    Simon Maybaum;Donna Mancini;Steve Xydas;Randall C. Starling

  • Regression of Cellular Hypertrophy After Left Ventricular Assist Device Support

    Andreas Zafeiridis;Valluvan Jeevanandam;Steven R. Houser;Kenneth B. Margulies

  • BET Bromodomains Mediate Transcriptional Pause Release in Heart Failure

    Priti Anand;Jonathan D. Brown;Charles Y. Lin;Jun Qi

  • Increased endothelin in experimental heart failure.

    Kenneth B. Margulies;Fredric L. Hildebrand;Amir Lerman;Mark A. Perrella

  • Phosphodiesterase 9A controls nitric-oxide-independent cGMP and hypertrophic heart disease

    Dong I. Lee;Guangshuo Zhu;Takashi Sasaki;Gun Sik Cho

  • Reciprocal Regulation of Myocardial microRNAs and Messenger RNA in Human Cardiomyopathy and Reversal of the microRNA Signature by Biomechanical Support

    Scot J. Matkovich;Derek J. Van Booven;Keith A. Youker;Guillermo Torre-Amione

  • Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization

    Dan E. Arking;Sara L. Pulit;Sara L. Pulit;Sara L. Pulit;Lia Crotti;Pim Van Der Harst

  • L-Type Ca2+ Channel Density and Regulation Are Altered in Failing Human Ventricular Myocytes and Recover After Support With Mechanical Assist Devices

    Xiongwen Chen;Valentino Piacentino;Satoshi Furukawa;Bruce Goldman

  • Effect of Inorganic Nitrate on Exercise Capacity in Heart Failure With Preserved Ejection Fraction

    Payman Zamani;Deepa Rawat;Prithvi Shiva-Kumar;Salvatore Geraci

  • Effects of Xanthine Oxidase Inhibition in Hyperuricemic Heart Failure Patients: The Xanthine Oxidase Inhibition for Hyperuricemic Heart Failure Patients (EXACT-HF) Study.

    Michael M. Givertz;Kevin J. Anstrom;Margaret M. Redfield;Anita Deswal

  • Detyrosinated microtubules buckle and bear load in contracting cardiomyocytes

    Patrick Robison;Matthew A. Caporizzo;Hossein Ahmadzadeh;Alexey I. Bogush

Frequent Co-Authors

Steven R. Houser
Steven R. Houser Temple University
John C. Burnett
John C. Burnett Mayo Clinic
Patrick T. Ellinor
Patrick T. Ellinor Harvard University
David A. Kass
David A. Kass Johns Hopkins University School of Medicine
Julio A. Chirinos
Julio A. Chirinos University of Pennsylvania
Christopher Newton-Cheh
Christopher Newton-Cheh Harvard University
Michael Morley
Michael Morley University of Pennsylvania
Donald M. Bers
Donald M. Bers University of California, Davis
Randall C. Starling
Randall C. Starling Cleveland Clinic
Bruce M. Psaty
Bruce M. Psaty University of Washington

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