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Jürgen K. Naggert

Jürgen K. Naggert

D-Index & Metrics

Biology and Biochemistry

D-Index
55
Citations
10408
World Ranking
15102
National Ranking
468

Overview

Jürgen K. Naggert is affiliated with the University of Salerno in Italy and focuses their research on molecular biology and ophthalmology, with additional work spanning cell biology, physiology, and neurology. Their publications reflect a strong emphasis on retinal development, retinal diseases, and treatments, prominently featuring studies related to retinal degeneration and related cellular processes.

The scientist's research covers diverse main fields, including biochemistry, genetics, molecular biology, and medicine. Their work often intersects subfields such as molecular biology, ophthalmology, and cell biology, contributing to the understanding of various physiological and neurological aspects related to vision and eye health.

Naggert's main research topics include retinal development and disorders, retinal diseases and treatments, investigations of retinoids in leukemia and cellular processes, endoplasmic reticulum stress and disease, lysosomal storage disorder research, single-cell and spatial transcriptomics, and mechanisms behind neuroinflammation and neurodegeneration.

Key recent publications by Naggert consist of:

  • Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss, 2020, Cells
  • Disruption in murine Eml1 perturbs retinal lamination during early development, 2020, Scientific Reports
  • Identification of Arhgef12 and Prkci as genetic modifiers of retinal dysplasia in the Crb1rd8 mouse model, 2022, PLoS Genetics
  • Single-Cell RNA Sequencing Reveals Molecular Features of Heterogeneity in the Murine Retinal Pigment Epithelium, 2022, International Journal of Molecular Sciences
  • A Splicing Mutation in Slc4a5 Results in Retinal Detachment and Retinal Pigment Epithelium Dysfunction, 2022, International Journal of Molecular Sciences

The scientist frequently publishes in journals such as the International Journal of Molecular Sciences, bioRxiv (Cold Spring Harbor Laboratory), Preprints.org, Cells, and Scientific Reports.

Frequent co-authors include Patsy M. Nishina, Gayle B. Collin, Mark P. Krebs, Lisa Stone, and Lillian F. Hyde, reflecting collaboration with researchers involved in retinal biology and related genetic studies.

Best Publications

  • Hyperproinsulinaemia in obese fat/fat mice associated with a carboxypeptidase E mutation which reduces enzyme activity

    Jürgen K. Naggert;Lloyd D. Fricker;Oleg Varlamov;Patsy M. Nishina

  • Mutations in ALMS1 cause obesity, type 2 diabetes and neurosensory degeneration in Alström syndrome

    Gayle B Collin;Jan D Marshall;Akihiro Ikeda;W Venus So

  • CRB1 is essential for external limiting membrane integrity and photoreceptor morphogenesis in the mammalian retina

    Adrienne K. Mehalow;Shuhei Kameya;Richard S. Smith;Norman L. Hawes

  • New Alström syndrome phenotypes based on the evaluation of 182 cases.

    Jan D. Marshall;Roderick T. Bronson;Gayle B. Collin;Anne D. Nordstrom

  • Alström syndrome: genetics and clinical overview.

    Jan D Marshall;Pietro Maffei;Gayle B Collin;Jürgen K Naggert

  • Excess cone cell proliferation due to lack of a functional NR2E3 causes retinal dysplasia and degeneration in rd7/rd7 mice.

    Neena B. Haider;Jürgen K. Naggert;Patsy M. Nishina

  • Alstr|[ouml]|m Syndrome

    Jan D Marshall;Sebastian Beck;Pietro Maffei;Jürgen K Naggert

  • Linkage of atherogenic lipoprotein phenotype to the low density lipoprotein receptor locus on the short arm of chromosome 19.

    Patsy M. Nishina;John P. Johnson;Jurgen K. Naggert;Ronald M. Krauss

  • Alms1-disrupted mice recapitulate human Alström syndrome

    G.B. Collin;E. Cyr;R. Bronson;J.D. Marshall

  • Molecular cloning and sequencing of cDNAs encoding the entire rat fatty acid synthase

    Christopher M. Amy;Andrzej Witkowski;Jurgen Naggert;Brenda Williams

  • Genetic analysis of a new mouse model for non-insulin-dependent diabetes.

    Jung Han Kim;Saunak Sen;Cindy S. Avery;Elizabeth Simpson

  • Multiple trait measurements in 43 inbred mouse strains capture the phenotypic diversity characteristic of human populations.

    Karen L. Svenson;Randy Von Smith;Phyllis A. Magnani;Heather R. Suetin

  • A comparison of cDNA, oligonucleotide, and Affymetrix GeneChip gene expression microarray platforms.

    Yong Woo;Jason Affourtit;Sandra Daigle;Agnes Viale

  • Spectrum of ALMS1 variants and evaluation of genotype‐phenotype correlations in Alström syndrome

    Jan D. Marshall;Elizabeth G. Hinman;Gayle B. Collin;Sebastian Beck

  • Mfrp, a gene encoding a frizzled related protein, is mutated in the mouse retinal degeneration 6

    Shuhei Kameya;Norman L. Hawes;Bo Chang;John R. Heckenlively

  • Aberrant actin cytoskeleton leads to accelerated proliferation of corneal epithelial cells in mice deficient for destrin (actin depolymerizing factor)

    Sakae Ikeda;Leslie A. Cunningham;Dawnalyn Boggess;Craig D. Hobson

  • Disruption of intraflagellar protein transport in photoreceptor cilia causes Leber congenital amaurosis in humans and mice.

    Karsten Boldt;Dorus A. Mans;Jungyeon Won;Jeroen van Reeuwijk

  • Retinal degeneration but not obesity is observed in null mutants of the tubby-like protein 1 gene

    Sakae Ikeda;Nima Shiva;Akihiro Ikeda;Richard S. Smith

  • The tubby-like proteins, a family with roles in neuronal development and function.

    Akihiro Ikeda;Patsy M. Nishina;Jürgen K. Naggert

  • Phenotypic characterization of polygenic type 2 diabetes in TALLYHO/JngJ mice.

    Jung Han Kim;Taryn P Stewart;Morvarid Soltani-Bejnood;Luan Wang

Frequent Co-Authors

Patsy M. Nishina
Patsy M. Nishina Tufts University
Neal S. Peachey
Neal S. Peachey Cleveland Clinic
Richard S. Smith
Richard S. Smith Laurentian University
Bo Chang
Bo Chang University of California, Los Angeles
Roberto Vettor
Roberto Vettor University of Padua
Beverly Paigen
Beverly Paigen University of Pennsylvania
Roderick T. Bronson
Roderick T. Bronson Harvard University
Gary A. Churchill
Gary A. Churchill The Jackson Laboratory
Angela Favaro
Angela Favaro University of Padua
John R. Heckenlively
John R. Heckenlively University of Michigan–Ann Arbor

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