World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
73
Citations
19611
World Ranking
2134
National Ranking
1037

Overview

Gulbu Uzel is affiliated with the National Institute of Allergy and Infectious Diseases in the United States and has contributed extensively to the fields of Medicine and Immunology and Microbiology. With a primary focus on immunodeficiency and autoimmune disorders, their research spans multiple intersecting domains including immune cell function and interaction, chronic lymphocytic leukemia research, T-cell and B-cell immunology, blood disorders and treatments, hematopoietic stem cell transplantation, and parvovirus B19 infection studies.

The body of work includes publications in several prominent journals, with frequent contributions to:

  • Journal of Allergy and Clinical Immunology
  • Journal of Clinical Immunology
  • Transplantation and Cellular Therapy
  • Journal of Human Immunity
  • The Journal of Experimental Medicine

Among recent papers authored or coauthored by Uzel are:

  • Coronavirus disease 2019 in patients with inborn errors of immunity: An international study, 2020, Journal of Allergy and Clinical Immunology
  • The expansion of human T-bet high CD21 low B cells is T cell dependent, 2021, Science Immunology
  • A randomized, placebo-controlled phase 3 trial of the PI3Kδ inhibitor leniolisib for activated PI3Kδ syndrome, 2022, Blood
  • Hematopoietic Cell Transplantation in Patients With Primary Immune Regulatory Disorders (PIRD): A Primary Immune Deficiency Treatment Consortium (PIDTC) Survey, 2020, Frontiers in Immunology
  • Human T-bet governs the generation of a distinct subset of CD11c high CD21 low B cells, 2022, Science Immunology

Uzel frequently collaborates with a number of researchers, including:

  • Steven M. Holland
  • Jenna Bergerson
  • Alexandra F. Freeman
  • V. Koneti Rao
  • Stuart G. Tangye

Their main fields of study focus extensively on medicine, with immunology and microbiology closely intertwined in their research interests. Subfields include immunology, genetics, epidemiology, oncology, and infectious diseases, reflecting a broad interdisciplinary approach.

Uzel's work has addressed various themes such as immune deficiencies, autoimmune disorder mechanisms, immune cell phenotypes, and treatments related to blood and immune system disorders, as well as transplantation therapies. The volume of publications and collaboration with established researchers highlight their active involvement in advancing understanding in these specialized areas.

Best Publications

  • STAT3 Mutations in the Hyper-IgE Syndrome

    Steven M. Holland;Frank R. DeLeo;Houda Z. Elloumi;Amy P. Hsu

  • Immune dysregulation in human subjects with heterozygous germline mutations in CTLA4

    Hye Sun Kuehn;Weiming Ouyang;Bernice Lo;Elissa K. Deenick;Elissa K. Deenick

  • Combined Immunodeficiency Associated with DOCK8 Mutations

    Qian Zhang;Jeremiah C. Davis;Ian T. Lamborn;Alexandra F. Freeman

  • GATA2 deficiency: a protean disorder of hematopoiesis, lymphatics and immunity

    Michael A. Spinner;Lauren A. Sanchez;Amy P. Hsu;Pamela A. Shaw

  • Dominant-activating germline mutations in the gene encoding the PI(3)K catalytic subunit p110δ result in T cell senescence and human immunodeficiency

    Carrie L Lucas;Hye Sun Kuehn;Fang Zhao;Julie E Niemela

  • Mutations in GATA2 are associated with the autosomal dominant and sporadic monocytopenia and mycobacterial infection (MonoMAC) syndrome

    Amy P. Hsu;Elizabeth P. Sampaio;Javed Khan;Katherine R. Calvo

  • Second messenger role for Mg2+ revealed by human T-cell immunodeficiency

    Feng-Yen Li;Benjamin Chaigne-Delalande;Chrysi Kanellopoulou;Jeremiah C. Davis

  • Residual NADPH oxidase and survival in chronic granulomatous disease.

    Douglas B. Kuhns;W. Gregory Alvord;Theo Heller;Jordan J. Feld

  • Common Severe Infections in Chronic Granulomatous Disease

    Beatriz E. Marciano;Christine Spalding;Alan Fitzgerald;Daphne Mann

  • Autosomal dominant and sporadic monocytopenia with susceptibility to mycobacteria, fungi, papillomaviruses, and myelodysplasia

    Donald C. Vinh;Smita Y. Patel;Gulbu Uzel;Victoria L. Anderson

  • Mg2+ Regulates Cytotoxic Functions of NK and CD8 T Cells in Chronic EBV Infection Through NKG2D

    Benjamin Chaigne-Delalande;Feng-Yen Li;Feng-Yen Li;Geraldine M. O’Connor;Marshall J. Lukacs

  • Coronavirus Disease 2019 in patients with inborn errors of immunity: an international study.

    Isabelle Meyts;Giorgia Bucciol;Isabella Quinti;Bénédicte Neven

  • First-in-human topical microbiome transplantation with Roseomonas mucosa for atopic dermatitis

    Ian A. Myles;Noah J. Earland;Erik D. Anderson;Ian N. Moore

  • Dominant gain-of-function STAT1 mutations in FOXP3 wild-type immune dysregulation-polyendocrinopathy-enteropathy-X-linked-like syndrome.

    Gulbu Uzel;Elizabeth P. Sampaio;Monica G. Lawrence;Amy P. Hsu

  • Defective Neutrophil Recruitment in Leukocyte Adhesion Deficiency Type I Disease Causes Local IL-17-driven Inflammatory Bone Loss

    Niki M. Moutsopoulos;Joanne Konkel;Mojgan Sarmadi;Mehmet A. Eskan

  • Redefined clinical features and diagnostic criteria in autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy

    Elise M.N. Ferre;Stacey R. Rose;Sergio D. Rosenzweig;Peter D. Burbelo

  • Effective “activated PI3Kδ syndrome”–targeted therapy with the PI3Kδ inhibitor leniolisib

    V. Koneti Rao;Sharon Webster;Virgil A. S. H. Dalm;Anna Šedivá

  • Loss-of-function mutations in the IL-21 receptor gene cause a primary immunodeficiency syndrome

    Daniel Kotlarz;Natalia Ziętara;Gulbu Uzel;Thomas Weidemann

  • Mutations in GATA2 cause human NK cell deficiency with specific loss of the CD56bright subset

    Emily M. Mace;Emily M. Mace;Amy P. Hsu;Linda Monaco-Shawver;George Makedonas;George Makedonas

  • Signal transducer and activator of transcription 1 (STAT1) gain-of-function mutations and disseminated coccidioidomycosis and histoplasmosis

    Elizabeth P. Sampaio;Elizabeth P. Sampaio;Amy P. Hsu;Joseph Pechacek;Hannelore I. Bax;Hannelore I. Bax

  • Viral infections in interferon-γ receptor deficiency

    Susan E. Dorman;Gulbu Uzel;Joachim Roesler;John S. Bradley

Frequent Co-Authors

Steven M. Holland
Steven M. Holland National Institute of Allergy and Infectious Diseases
Stuart G. Tangye
Stuart G. Tangye Garvan Institute of Medical Research
Cindy S. Ma
Cindy S. Ma Garvan Institute of Medical Research
Alexandra F. Freeman
Alexandra F. Freeman National Institute of Allergy and Infectious Diseases
Elissa K. Deenick
Elissa K. Deenick Garvan Institute of Medical Research
Amy P. Hsu
Amy P. Hsu National Institutes of Health
Jordan S. Orange
Jordan S. Orange University of Pennsylvania
Elizabeth P. Sampaio
Elizabeth P. Sampaio National Institutes of Health
Helen C. Su
Helen C. Su National Institutes of Health
Stefania Pittaluga
Stefania Pittaluga National Institutes of Health

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

For those interested in expanding their expertise beyond Immunology, exploring related healthcare degrees can open diverse career opportunities. Many professionals consider transitioning into nursing roles, which offer both rewarding patient care experiences and strong job growth.

If you don’t have a nursing background but want to enter the field, there are excellent online RN programs for non nurses available. These programs are designed to bring non-nurses up to speed quickly and effectively.

For quicker entry into nursing, you might explore the easiest accelerated nursing programs to get into. These streamline the BSN curriculum for those with prior college credit or healthcare experience.

If you’re focusing on licensed practical nurse roles, programs with simpler admission requirements can ease your path. The lpn programs with easiest admission requirements help many students overcome initial barriers.

Finally, to advance clinical practice, consider exploring nurse practitioner paths. Identifying which nurse practitioner program is easiest to enroll in can help you progress without unnecessary delay.

Best Scientists Citing Gulbu Uzel

Trending Scientists