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Microbiology

D-Index
69
Citations
26926
World Ranking
1995
National Ranking
844

Overview

Helen C. Su is affiliated with the National Institutes of Health in the United States. Their research spans multiple fields including Medicine, Immunology and Microbiology, and Biochemistry, Genetics and Molecular Biology, with a demonstrated focus on immunology and infectious diseases.

Key topics of their work include:

  • Immunodeficiency and Autoimmune Disorders
  • COVID-19 Clinical Research Studies
  • SARS-CoV-2 and COVID-19 Research
  • Immune Cell Function and Interaction
  • Blood disorders and treatments
  • Kawasaki Disease and Coronary Complications
  • Long-Term Effects of COVID-19

Helen C. Su has contributed research published in frequent venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Clinical Immunology
  • The Journal of Experimental Medicine
  • Journal of Human Immunity
  • Journal of Allergy and Clinical Immunology

Their recent papers include:

  • "Autoantibodies against type I IFNs in patients with life-threatening COVID-19" (2020, Science)
  • "Human Inborn Errors of Immunity: 2022 Update on the Classification from the International Union of Immunological Societies Expert Committee" (2022, Journal of Clinical Immunology)
  • "The 2022 Update of IUIS Phenotypical Classification for Human Inborn Errors of Immunity" (2022, Journal of Clinical Immunology)
  • "Human genetic and immunological determinants of critical COVID-19 pneumonia" (2022, Nature)
  • "An immune-based biomarker signature is associated with mortality in COVID-19 patients" (2020, JCI Insight)

Frequent coauthors in Helen C. Su's research collaborations include:

  • Luigi D. Notarangelo
  • Steven M. Holland
  • Kerry Dobbs
  • Ottavia M. Delmonte
  • Jean-Laurent Casanova

Best Publications

  • Autoantibodies against type I IFNs in patients with life-threatening COVID-19.

    Paul Bastard;Paul Bastard;Paul Bastard;Lindsey B. Rosen;Qian Zhang;Eleftherios Michailidis

  • Inborn errors of type I IFN immunity in patients with life-threatening COVID-19

    Qian Zhang;Paul Bastard;Paul Bastard;Zhiyong Liu;Jérémie Le Pen

  • Regulation of an ATG7-beclin 1 Program of Autophagic Cell Death by Caspase-8

    Li Yu;Ajjai Alva;Helen Su;Parmesh Dutt

  • Immune dysregulation in human subjects with heterozygous germline mutations in CTLA4

    Hye Sun Kuehn;Weiming Ouyang;Bernice Lo;Elissa K. Deenick;Elissa K. Deenick

  • Combined Immunodeficiency Associated with DOCK8 Mutations

    Qian Zhang;Jeremiah C. Davis;Ian T. Lamborn;Alexandra F. Freeman

  • Patients with LRBA deficiency show CTLA4 loss and immune dysregulation responsive to abatacept therapy

    Bernice Lo;Kejian Zhang;Wei Lu;Lixin Zheng

  • Second messenger role for Mg2+ revealed by human T-cell immunodeficiency

    Feng-Yen Li;Benjamin Chaigne-Delalande;Chrysi Kanellopoulou;Jeremiah C. Davis

  • Early-onset lymphoproliferation and autoimmunity caused by germline STAT3 gain-of-function mutations

    Joshua D. Milner;Tiphanie P. Vogel;Lisa Forbes;Chi A. Ma

  • Autoantibodies neutralizing type I IFNs are present in ~ 4% of uninfected individuals over 70 years old and account for ~ 20% of COVID-19 deaths.

    Paul Bastard;Adrian Gervais;Adrian Gervais;Tom Le Voyer;Tom Le Voyer;Jérémie Rosain;Jérémie Rosain

  • Human genetic and immunological determinants of critical COVID-19 pneumonia

    Unknown

  • Revised diagnostic criteria and classification for the autoimmune lymphoproliferative syndrome (ALPS): report from the 2009 NIH International Workshop.

    Joao B. Oliveira;Jack J. Bleesing;Umberto Dianzani;Thomas A. Fleisher

  • Requirement for Caspase-8 in NF-κB Activation by Antigen Receptor

    Helen Su;Nicolas Bidère;Lixin Zheng;Alan Cubre

  • Interferon-α/β inhibition of interleukin 12 and interferon-γ production in vitro and endogenously during viral infection

    Leslie P. Cousens;Jordan S. Orange;Helen C. Su;Christine A. Biron

  • X-linked recessive TLR7 deficiency in ~1% of men under 60 years old with life-threatening COVID-19.

    Takaki Asano;Bertrand Boisson;Bertrand Boisson;Bertrand Boisson;Fanny Onodi;Daniela Matuozzo;Daniela Matuozzo

  • Mg2+ Regulates Cytotoxic Functions of NK and CD8 T Cells in Chronic EBV Infection Through NKG2D

    Benjamin Chaigne-Delalande;Feng-Yen Li;Feng-Yen Li;Geraldine M. O’Connor;Marshall J. Lukacs

  • Immunopathological signatures in multisystem inflammatory syndrome in children and pediatric COVID-19

    Unknown

  • An immune-based biomarker signature is associated with mortality in COVID-19 patients.

    Michael S. Abers;Ottavia M. Delmonte;Emily E. Ricotta;Jonathan Fintzi

  • DOCK8 Deficiency: Clinical and Immunological Phenotype and Treatment Options - a Review of 136 Patients

    Susanne E. Aydin;Sara Sebnem Kilic;Caner Aytekin;Ashish Kumar

  • Heterozygous splice mutation in PIK3R1 causes human immunodeficiency with lymphoproliferation due to dominant activation of PI3K

    Carrie L. Lucas;Yu Zhang;Anthony Venida;Ying Wang

  • Preexisting autoantibodies to type I IFNs underlie critical COVID-19 pneumonia in patients with APS-1.

    Paul Bastard;Paul Bastard;Paul Bastard;Elizaveta Orlova;Leila Sozaeva;Romain Lévy;Romain Lévy

  • Autosomal recessive phosphoglucomutase 3 (PGM3) mutations link glycosylation defects to atopy, immune deficiency, autoimmunity, and neurocognitive impairment

    Yu Zhang;Xiaomin Yu;Mie Ichikawa;Jonathan J. Lyons

  • GENETIC DISORDERS OF PROGRAMMED CELL DEATH IN THE IMMUNE SYSTEM

    Nicolas Bidère;Helen C. Su;Michael J. Lenardo

Frequent Co-Authors

Michael J. Lenardo
Michael J. Lenardo National Institute of Allergy and Infectious Diseases
Laurent Abel
Laurent Abel Université Paris Cité
Alexandra F. Freeman
Alexandra F. Freeman National Institute of Allergy and Infectious Diseases
Shen-Ying Zhang
Shen-Ying Zhang Rockefeller University
Jean-Laurent Casanova
Jean-Laurent Casanova The University of Texas Southwestern Medical Center
Stuart G. Tangye
Stuart G. Tangye Garvan Institute of Medical Research
Steven M. Holland
Steven M. Holland National Institute of Allergy and Infectious Diseases
Luigi D. Notarangelo
Luigi D. Notarangelo National Institutes of Health
Gulbu Uzel
Gulbu Uzel National Institute of Allergy and Infectious Diseases

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