D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Immunology D-index 42 Citations 8,596 74 World Ranking 3810 National Ranking 170

Overview

What is she best known for?

The fields of study she is best known for:

  • Gene
  • Immune system
  • T cell

Elissa K. Deenick mainly focuses on Immunology, Cellular differentiation, Cytotoxic T cell, Immune system and B-1 cell. Her work carried out in the field of Immunology brings together such families of science as Gene rearrangement and Chronic Candidiasis, Candida albicans. Her study focuses on the intersection of Cellular differentiation and fields such as Cell biology with connections in the field of Naive B cell.

Her research in Cytotoxic T cell intersects with topics in Haploinsufficiency, CTLA4 Haploinsufficiency, Immune dysregulation and Germline. As a part of the same scientific family, Elissa K. Deenick mostly works in the field of Immune system, focusing on Germline mutation and, on occasion, PI3K/AKT/mTOR pathway, Protein kinase B, IL-2 receptor and Molecular biology. Her Immunity research is multidisciplinary, incorporating perspectives in Humoral immunity, Antibody, Autoimmunity and Function.

Her most cited work include:

  • Immune dysregulation in human subjects with heterozygous germline mutations in CTLA4 (485 citations)
  • Immune dysregulation in human subjects with heterozygous germline mutations in CTLA4 (485 citations)
  • Dominant-activating germline mutations in the gene encoding the PI(3)K catalytic subunit p110δ result in T cell senescence and human immunodeficiency (379 citations)

What are the main themes of her work throughout her whole career to date?

Her primary areas of study are Immunology, Cell biology, Immune system, Cytotoxic T cell and Cellular differentiation. Her Immunology and B cell, Antibody, Humoral immunity, Immunity and T cell investigations all form part of her Immunology research activities. Elissa K. Deenick has included themes like Receptor, Naive B cell, CD40 and Transcription factor in her Cell biology study.

The concepts of her Immune system study are interwoven with issues in Mutation, Germinal center and Cytokine. Her work investigates the relationship between Cytotoxic T cell and topics such as CD8 that intersect with problems in Cancer research and Virology. Her Cellular differentiation research includes themes of Cell culture, Germline mutation, Cell growth and Antigen.

She most often published in these fields:

  • Immunology (111.21%)
  • Cell biology (62.93%)
  • Immune system (60.34%)

What were the highlights of her more recent work (between 2018-2021)?

  • Immunology (111.21%)
  • Immune system (60.34%)
  • Antibody (33.62%)

In recent papers she was focusing on the following fields of study:

Her main research concerns Immunology, Immune system, Antibody, Cancer research and Autoimmunity. Her study in B cell and Humoral immunity is done as part of Immunology. Her work is dedicated to discovering how B cell, Peripheral tolerance are connected with Germinal center and other disciplines.

Her study on Immunodeficiency, Immune regulation and Immune dysregulation is often connected to Goldilocks principle as part of broader study in Immune system. Her B-cell activation study in the realm of Antibody interacts with subjects such as 2019-20 coronavirus outbreak and Severe acute respiratory syndrome coronavirus 2. Her Cancer research study incorporates themes from Everolimus, CD8 and CTLA4 Haploinsufficiency.

Between 2018 and 2021, her most popular works were:

  • Activating PIK3CD mutations impair human cytotoxic lymphocyte differentiation and function and EBV immunity (29 citations)
  • Activating PIK3CD mutations impair human cytotoxic lymphocyte differentiation and function and EBV immunity (29 citations)
  • A divergent transcriptional landscape underpins the development and functional branching of MAIT cells (23 citations)

In her most recent research, the most cited papers focused on:

  • Gene
  • Immune system
  • T cell

Elissa K. Deenick focuses on CD8, Cancer research, Cell biology, Transcription factor and Transcriptome. CD8 is the subject of her research, which falls under Immune system. Her research integrates issues of Plasma cell, Carboxyfluorescein succinimidyl ester, Cytokine and Immunity in her study of Cancer research.

Her Cell biology research integrates issues from Cell, Cellular differentiation, Mucosal associated invariant T cell, Cell growth and Signaling lymphocytic activation molecule.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Immune dysregulation in human subjects with heterozygous germline mutations in CTLA4

Hye Sun Kuehn;Weiming Ouyang;Bernice Lo;Elissa K. Deenick;Elissa K. Deenick.
Science (2014)

740 Citations

The origins, function, and regulation of T follicular helper cells.

Cindy S. Ma;Elissa K. Deenick;Elissa K. Deenick;Marcel Batten;Marcel Batten;Stuart G. Tangye;Stuart G. Tangye.
Journal of Experimental Medicine (2012)

622 Citations

The good, the bad and the ugly - TFH cells in human health and disease.

Stuart G. Tangye;Cindy S. Ma;Cindy S. Ma;Robert Brink;Robert Brink;Elissa K. Deenick;Elissa K. Deenick.
Nature Reviews Immunology (2013)

546 Citations

Dominant-activating germline mutations in the gene encoding the PI(3)K catalytic subunit p110δ result in T cell senescence and human immunodeficiency

Carrie L Lucas;Hye Sun Kuehn;Fang Zhao;Julie E Niemela.
Nature Immunology (2014)

541 Citations

B cell-intrinsic signaling through IL-21 receptor and STAT3 is required for establishing long-lived antibody responses in humans

Danielle T. Avery;Elissa K. Deenick;Elissa K. Deenick;Cindy S. Ma;Cindy S. Ma;Santi Suryani;Santi Suryani.
Journal of Experimental Medicine (2010)

385 Citations

Early commitment of naïve human CD4(+) T cells to the T follicular helper (T(FH)) cell lineage is induced by IL-12.

Cindy S Ma;Santi Suryani;Santi Suryani;Danielle T Avery;Anna Chan.
Immunology and Cell Biology (2009)

370 Citations

Follicular helper T cell differentiation requires continuous antigen presentation that is independent of unique B cell signaling

Elissa K. Deenick;Anna Chan;Cindy S. Ma;Cindy S. Ma;Dominique Gatto;Dominique Gatto.
Immunity (2010)

348 Citations

Impairment of immunity to Candida and Mycobacterium in humans with bi-allelic RORC mutations

Satoshi Okada;Satoshi Okada;Janet G Markle;Elissa K Deenick;Elissa K Deenick;Federico Mele.
Science (2015)

341 Citations

Intrinsic Differences in the Proliferation of Naive and Memory Human B Cells as a Mechanism for Enhanced Secondary Immune Responses

Stuart G. Tangye;Stuart G. Tangye;Danielle T. Avery;Elissa K. Deenick;Elissa K. Deenick;Philip D. Hodgkin;Philip D. Hodgkin.
Journal of Immunology (2003)

325 Citations

Functional STAT3 deficiency compromises the generation of human T follicular helper cells

Cindy S. Ma;Cindy S. Ma;Danielle T. Avery;Anna Chan;Marcel Batten;Marcel Batten.
Blood (2012)

305 Citations

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