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Immunology

D-Index
45
Citations
10713
World Ranking
4675
National Ranking
204

Overview

Elissa K. Deenick is affiliated with the Garvan Institute of Medical Research in Australia and has a significant body of work in immunology and microbiology. Their research spans 53 publications in these fields, with additional contributions to medicine. The scientist's subfields of study include immunology, genetics, molecular biology, infectious diseases, and epidemiology.

The research topics frequently addressed by Deenick cover areas such as immunodeficiency and autoimmune disorders, T-cell and B-cell immunology, immune cell function and interaction, chronic lymphocytic leukemia research, blood disorders and treatments, inflammasome and immune disorders, and diabetes and associated disorders.

Deenick has coauthored numerous papers with several frequent collaborators. Among these are Stuart G. Tangye, Robert Brink, Julia Bier, Stephanie Ruiz-Diaz, and Tri Giang Phan.

The scientist has been published regularly in various venues, including Immunology and Cell Biology and The Journal of Immunology, each with four publications. They have also contributed to bioRxiv (Cold Spring Harbor Laboratory), The Journal of Experimental Medicine, and Journal of Clinical Immunology.

Recent research papers by Elissa K. Deenick include the following:

  • Inborn errors of human B cell development, differentiation, and function, 2023, The Journal of Experimental Medicine
  • Genomic Spectrum and Phenotypic Heterogeneity of Human IL-21 Receptor Deficiency, 2021, Journal of Clinical Immunology
  • NK Cells Regulate CD8+ T Cell Mediated Autoimmunity, 2020, Frontiers in Cellular and Infection Microbiology
  • Tracking the clonal dynamics of SARS-CoV-2-specific T cells in children and adults with mild/asymptomatic COVID-19, 2022, Clinical Immunology
  • Human PIK3R1 mutations disrupt lymphocyte differentiation to cause activated PI3Kδ syndrome 2, 2023, The Journal of Experimental Medicine

Best Publications

  • Immune dysregulation in human subjects with heterozygous germline mutations in CTLA4

    Hye Sun Kuehn;Weiming Ouyang;Bernice Lo;Elissa K. Deenick;Elissa K. Deenick

  • Dominant-activating germline mutations in the gene encoding the PI(3)K catalytic subunit p110δ result in T cell senescence and human immunodeficiency

    Carrie L Lucas;Hye Sun Kuehn;Fang Zhao;Julie E Niemela

  • The origins, function, and regulation of T follicular helper cells.

    Cindy S. Ma;Elissa K. Deenick;Elissa K. Deenick;Marcel Batten;Marcel Batten;Stuart G. Tangye;Stuart G. Tangye

  • The good, the bad and the ugly - TFH cells in human health and disease.

    Stuart G. Tangye;Cindy S. Ma;Cindy S. Ma;Robert Brink;Robert Brink;Elissa K. Deenick;Elissa K. Deenick

  • B cell-intrinsic signaling through IL-21 receptor and STAT3 is required for establishing long-lived antibody responses in humans

    Danielle T. Avery;Elissa K. Deenick;Elissa K. Deenick;Cindy S. Ma;Cindy S. Ma;Santi Suryani;Santi Suryani

  • Impairment of immunity to Candida and Mycobacterium in humans with bi-allelic RORC mutations

    Satoshi Okada;Satoshi Okada;Janet G Markle;Elissa K Deenick;Elissa K Deenick;Federico Mele

  • Early commitment of naïve human CD4(+) T cells to the T follicular helper (T(FH)) cell lineage is induced by IL-12.

    Cindy S Ma;Santi Suryani;Santi Suryani;Danielle T Avery;Anna Chan

  • Follicular helper T cell differentiation requires continuous antigen presentation that is independent of unique B cell signaling

    Elissa K. Deenick;Anna Chan;Cindy S. Ma;Cindy S. Ma;Dominique Gatto;Dominique Gatto

  • Intrinsic Differences in the Proliferation of Naive and Memory Human B Cells as a Mechanism for Enhanced Secondary Immune Responses

    Stuart G. Tangye;Stuart G. Tangye;Danielle T. Avery;Elissa K. Deenick;Elissa K. Deenick;Philip D. Hodgkin;Philip D. Hodgkin

  • Functional STAT3 deficiency compromises the generation of human T follicular helper cells

    Cindy S. Ma;Cindy S. Ma;Danielle T. Avery;Anna Chan;Marcel Batten;Marcel Batten

  • Dock8 mutations cripple B cell immunological synapses, germinal centers and long-lived antibody production.

    Katrina L Randall;Katrina L Randall;Teresa Lambe;Andy L Johnson;Andy L Johnson;Bebhinn Treanor

  • Human T follicular helper (Tfh) cells and disease

    Cindy S Ma;Elissa K Deenick

  • Stochastic Model of T Cell Proliferation: A Calculus Revealing IL-2 Regulation of Precursor Frequencies, Cell Cycle Time, and Survival

    Elissa K. Deenick;Amanda V. Gett;Philip D. Hodgkin

  • Monogenic mutations differentially affect the quantity and quality of T follicular helper cells in patients with human primary immunodeficiencies

    Cindy S. Ma;Cindy S. Ma;Natalie Wong;Geetha Rao;Danielle T. Avery

  • Naive and memory human B cells have distinct requirements for STAT3 activation to differentiate into antibody-secreting plasma cells

    Elissa K. Deenick;Elissa K. Deenick;Danielle T. Avery;Anna Chan;Lucinda J. Berglund;Lucinda J. Berglund;Lucinda J. Berglund

  • A recessive form of hyper-IgE syndrome by disruption of ZNF341-dependent STAT3 transcription and activity

    Vivien Béziat;Vivien Béziat;Juan Li;Jian-Xin Lin;Cindy S. Ma;Cindy S. Ma

  • Human IFN-γ immunity to mycobacteria is governed by both IL-12 and IL-23

    Rubén Martínez-Barricarte;Janet G. Markle;Cindy S. Ma;Elissa K. Deenick

  • T follicular helper cells have distinct modes of migration and molecular signatures in naive and memory immune responses.

    Dan Suan;Dan Suan;Akira Nguyen;Akira Nguyen;Imogen Moran;Imogen Moran;Katherine Bourne

  • TCR affinity and negative regulation limit autoimmunity

    Matthew A Gronski;Jonathan M Boulter;Demetrius Moskophidis;Linh T Nguyen

  • Quantitative analysis of lymphocyte differentiation and proliferation in vitro using carboxyfluorescein diacetate succinimidyl ester.

    J Hasbold;AV Gett;JS Rush;E Deenick

  • Switching to IgG3, IgG2b, and IgA Is Division Linked and Independent, Revealing a Stochastic Framework for Describing Differentiation

    Elissa K. Deenick;Jhagvaral Hasbold;Philip D. Hodgkin

Frequent Co-Authors

Stuart G. Tangye
Stuart G. Tangye Garvan Institute of Medical Research
Cindy S. Ma
Cindy S. Ma Garvan Institute of Medical Research
Stéphanie Boisson-Dupuis
Stéphanie Boisson-Dupuis Université Paris Cité
Robert Brink
Robert Brink University of New South Wales
Jean-Laurent Casanova
Jean-Laurent Casanova The University of Texas Southwestern Medical Center
Matthew C. Cook
Matthew C. Cook Australian National University
Danielle T. Avery
Danielle T. Avery Garvan Institute of Medical Research
Tri Giang Phan
Tri Giang Phan Garvan Institute of Medical Research
Jacinta Bustamante
Jacinta Bustamante Rockefeller University
Martyn A. French
Martyn A. French University of Western Australia

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