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Biology and Biochemistry

D-Index
44
Citations
11078
World Ranking
19215
National Ranking
571

Overview

Danielle T. Avery is affiliated with the Garvan Institute of Medical Research in Australia. Their research primarily spans immunology and microbiology, with a strong focus on medicine. The scientist's work extensively covers subfields including immunology, oncology, genetics, epidemiology, and pathology and forensic medicine.

The main topics explored in Avery's research involve immune cell function and interaction, immunodeficiency and autoimmune disorders, and T-cell and B-cell immunology. Additional areas include CAR-T cell therapy research, chronic lymphocytic leukemia research, blood disorders and treatments, as well as Whipple's disease and interleukins.

Avery has contributed multiple papers to notable scientific journals. Recent publications include:

  • The expansion of human T-bet high CD21 low B cells is T cell dependent, 2021, Science Immunology
  • Human T-bet governs the generation of a distinct subset of CD11c high CD21 low B cells, 2022, Science Immunology
  • STAT3 gain-of-function mutations connect leukemia with autoimmune disease by pathological NKG2Dhi CD8+ T cell dysregulation and accumulation, 2022, Immunity
  • Human PIK3R1 mutations disrupt lymphocyte differentiation to cause activated PI3Kδ syndrome 2, 2023, The Journal of Experimental Medicine
  • Inherited human c-Rel deficiency disrupts myeloid and lymphoid immunity to multiple infectious agents, 2021, Journal of Clinical Investigation

Frequent co-authors in Avery's work include:

  • S. Cindy
  • Stuart G. Tangye
  • Gülbû Uzel
  • Jean-Laurent Casanova
  • Geetha Rao

The scientist's research outputs have been published repeatedly in several key journals, notably:

  • Science Immunology (2 publications)
  • Immunity (2 publications)
  • The Journal of Experimental Medicine (2 publications)
  • Journal of Clinical Immunology (2 publications)
  • Journal of Clinical Investigation (1 publication)

Best Publications

  • Immune dysregulation in human subjects with heterozygous germline mutations in CTLA4

    Hye Sun Kuehn;Weiming Ouyang;Bernice Lo;Elissa K. Deenick;Elissa K. Deenick

  • Dominant-activating germline mutations in the gene encoding the PI(3)K catalytic subunit p110δ result in T cell senescence and human immunodeficiency

    Carrie L Lucas;Hye Sun Kuehn;Fang Zhao;Julie E Niemela

  • BAFF selectively enhances the survival of plasmablasts generated from human memory B cells

    Danielle T. Avery;Susan L. Kalled;Julia I. Ellyard;Christine Ambrose

  • Cytokine-Mediated Regulation of Human B Cell Differentiation into Ig-Secreting Cells: Predominant Role of IL-21 Produced by CXCR5+ T Follicular Helper Cells

    Vanessa L. Bryant;Vanessa L. Bryant;Vanessa L. Bryant;Cindy S. Ma;Cindy S. Ma;Danielle T. Avery;Danielle T. Avery;Ying Li

  • B cell-intrinsic signaling through IL-21 receptor and STAT3 is required for establishing long-lived antibody responses in humans

    Danielle T. Avery;Elissa K. Deenick;Elissa K. Deenick;Cindy S. Ma;Cindy S. Ma;Santi Suryani;Santi Suryani

  • Impairment of immunity to Candida and Mycobacterium in humans with bi-allelic RORC mutations

    Satoshi Okada;Satoshi Okada;Janet G Markle;Elissa K Deenick;Elissa K Deenick;Federico Mele

  • Early commitment of naïve human CD4(+) T cells to the T follicular helper (T(FH)) cell lineage is induced by IL-12.

    Cindy S Ma;Santi Suryani;Santi Suryani;Danielle T Avery;Anna Chan

  • CXCR5 Expressing Human Central Memory CD4 T Cells and Their Relevance for Humoral Immune Responses

    Nina Chevalier;Nina Chevalier;David Jarrossay;Edwin Ho;Danielle T Avery

  • Intrinsic Differences in the Proliferation of Naive and Memory Human B Cells as a Mechanism for Enhanced Secondary Immune Responses

    Stuart G. Tangye;Stuart G. Tangye;Danielle T. Avery;Elissa K. Deenick;Elissa K. Deenick;Philip D. Hodgkin;Philip D. Hodgkin

  • Human TYK2 deficiency: Mycobacterial and viral infections without hyper-IgE syndrome

    Alexandra Y. Kreins;Alexandra Y. Kreins;Michael J. Ciancanelli;Satoshi Okada;Xiao Fei Kong

  • Functional STAT3 deficiency compromises the generation of human T follicular helper cells

    Cindy S. Ma;Cindy S. Ma;Danielle T. Avery;Anna Chan;Marcel Batten;Marcel Batten

  • IL-21-Induced Isotype Switching to IgG and IgA by Human Naive B Cells Is Differentially Regulated by IL-4

    Danielle T. Avery;Vanessa L. Bryant;Vanessa L. Bryant;Vanessa L. Bryant;Cindy S. Ma;Cindy S. Ma;Rene de Waal Malefyt

  • Resting human memory B cells are intrinsically programmed for enhanced survival and responsiveness to diverse stimuli compared to naive B cells.

    Kim L. Good;Danielle T. Avery;Danielle T. Avery;Stuart G. Tangye;Stuart G. Tangye

  • Isotype switching by human B cells is division-associated and regulated by cytokines.

    Stuart G. Tangye;Stuart G. Tangye;Anthea Ferguson;Anthea Ferguson;Danielle T. Avery;Cindy S. Ma;Cindy S. Ma

  • A Division-Linked Mechanism for the Rapid Generation of Ig-Secreting Cells from Human Memory B Cells

    Stuart G. Tangye;Danielle T. Avery;Philip D. Hodgkin;Philip D. Hodgkin

  • Expansion of Functionally Immature Transitional B Cells Is Associated with Human-Immunodeficient States Characterized by Impaired Humoral Immunity

    Amanda K. Cuss;Amanda K. Cuss;Danielle T. Avery;Jennifer L. Cannons;Li Jun Yu

  • Functional Consequences of Interactions between Human NKR-P1A and Its Ligand LLT1 Expressed on Activated Dendritic Cells and B Cells

    David B. Rosen;Wei Cao;Danielle T. Avery;Stuart G. Tangye

  • Naive and memory human B cells have distinct requirements for STAT3 activation to differentiate into antibody-secreting plasma cells

    Elissa K. Deenick;Elissa K. Deenick;Danielle T. Avery;Anna Chan;Lucinda J. Berglund;Lucinda J. Berglund;Lucinda J. Berglund

  • Increased Expression of CD27 on Activated Human Memory B Cells Correlates with Their Commitment to the Plasma Cell Lineage

    Danielle T. Avery;Julia I. Ellyard;Julia I. Ellyard;Fabienne Mackay;Lynn M. Corcoran

  • CCR6 Defines Memory B Cell Precursors in Mouse and Human Germinal Centers, Revealing Light-Zone Location and Predominant Low Antigen Affinity

    Dan Suan;Dan Suan;Nike J. Kräutler;Nike J. Kräutler;Jesper L.V. Maag;Danyal Butt

Frequent Co-Authors

Stuart G. Tangye
Stuart G. Tangye Garvan Institute of Medical Research
Cindy S. Ma
Cindy S. Ma Garvan Institute of Medical Research
Stéphanie Boisson-Dupuis
Stéphanie Boisson-Dupuis Université Paris Cité
Laurent Abel
Laurent Abel Université Paris Cité
Elissa K. Deenick
Elissa K. Deenick Garvan Institute of Medical Research
Jean-Laurent Casanova
Jean-Laurent Casanova The University of Texas Southwestern Medical Center
Jacinta Bustamante
Jacinta Bustamante Rockefeller University
Philip D. Hodgkin
Philip D. Hodgkin Walter and Eliza Hall Institute of Medical Research
Robert Brink
Robert Brink University of New South Wales

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