2026 Michel Chrétien: Biology and Biochemistry Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Biology and Biochemistry	97	1756	1581	50	45	488	33032

Research.com Recognitions

2023 - Research.com Biology and Biochemistry in Canada Leader Award
2009 - Fellow of the Royal Society, United Kingdom
1995 - Fellow of the American Association for the Advancement of Science (AAAS)
1981 - Fellow of the Royal Society of Canada Academy of Science

Overview

Michel Chrétien is affiliated with the University of Montreal in Canada. Their research spans several fields, primarily Medicine and Biochemistry, Genetics and Molecular Biology, with notable contributions to Surgery, Molecular Biology, Epidemiology, Nutrition and Dietetics, and Computational Theory and Mathematics.

Their research topics cover a variety of subjects including:

Lipoproteins and Cardiovascular Health
Inflammasome and immune disorders
Adipokines, Inflammation, and Metabolic Diseases
Computational Drug Discovery Methods
Atherosclerosis and Cardiovascular Diseases
Cancer, Lipids, and Metabolism
Phytochemicals and Medicinal Plants

Michel Chrétien has contributed to a number of papers, some of which include:

"Isoquercetin as an Anti-Covid-19 Medication: A Potential to Realize" (2022), published in Frontiers in Pharmacology
"The loss-of-function PCSK9Q152H variant increases ER chaperones GRP78 and GRP94 and protects against liver injury" (2020), published in Journal of Clinical Investigation
"White Adipose Tissue Surface Expression of LDLR and CD36 is Associated with Risk Factors for Type 2 Diabetes in Adults with Obesity" (2020), published in Obesity
"Lower plasma PCSK9 in normocholesterolemic subjects is associated with upregulated adipose tissue surface-expression of LDLR and CD36 and NLRP3 inflammasome" (2021), published in Physiological Reports
"Quercetin inhibits SARS-CoV-2 infection and prevents syncytium formation by cells co-expressing the viral spike protein and human ACE2" (2024), published in Virology Journal

Frequent co-authors in their work include Majambu Mbikay, Simon Bissonnette, Valérie Lamantia, Yannick Cyr, and May Faraj.

Michel Chrétien's publications have appeared in several journals repeatedly, such as:

Frontiers in Pharmacology
Virology Journal
Journal of Clinical Investigation
Scientific Reports
Obesity

Recognition for their work includes these awards:

Fellow of the Royal Society of Canada (1981), Academy of Science
Fellow of the American Association for the Advancement of Science (AAAS) (1995)
Fellow of the Royal Society, United Kingdom (2009)

Best Publications

The secretory proprotein convertase neural apoptosis-regulated convertase 1 (NARC-1): Liver regeneration and neuronal differentiation

Nabil G. Seidah;Suzanne Benjannet;Louise Wickham;Jadwiga Marcinkiewicz

1449
Citations
Proprotein and prohormone convertases: a family of subtilases generating diverse bioactive polypeptides.

Nabil G Seidah;Michel Chrétien

921
Citations
NARC-1/PCSK9 and Its Natural Mutants ZYMOGEN CLEAVAGE AND EFFECTS ON THE LOW DENSITY LIPOPROTEIN (LDL) RECEPTOR AND LDL CHOLESTEROL

Suzanne Benjannet;David Rhainds;Rachid Essalmani;Janice Mayne

772
Citations
PC1 and PC2 are proprotein convertases capable of cleaving proopiomelanocortin at distinct pairs of basic residues.

S Benjannet;N Rondeau;R Day;M Chrétien

768
Citations
PCSK9: A Key Modulator of Cardiovascular Health

Nabil G. Seidah;Zuhier Awan;Michel Chrétien;Majambu Mbikay

640
Citations
Cloning and primary sequence of a mouse candidate prohormone convertase PC1 homologous to PC2, Furin, and Kex2: distinct chromosomal localization and messenger RNA distribution in brain and pituitary compared to PC2.

N. G. Seidah;M. Marcinkiewicz;S. Benjannet;L. Gaspar

635
Citations
cDNA sequence of two distinct pituitary proteins homologous to Kex2 and furin gene products: tissue-specific mRNAs encoding candidates for pro-hormone processing proteinases.

N.G. Seidah;L. Gaspar;P. Mion;M. Marcinkiewicz

596
Citations
The family of subtilisin/kexin like pro-protein and pro-hormone convertases: divergent or shared functions.

N.G. Seidah;M. Chrétien;R. Day

489
Citations
Cellular processing of the neurotrophin precursors of NT3 and BDNF by the mammalian proprotein convertases

Nabil G. Seidah;Suzanne Benjannet;Sangeeta Pareek;Michel Chrétien

460
Citations
Post-translational processing of beta-secretase (beta-amyloid-converting enzyme) and its ectodomain shedding. The pro- and transmembrane/cytosolic domains affect its cellular activity and amyloid-beta production.

Suzanne Benjannet;Aram Elagoz;Louise Wickham;Maya Mamarbachi

443
Citations
Amino acids of the Torpedo marmorata acetylcholine receptor .alpha. subunit labeled by a photoaffinity ligand for the acetylcholine binding site

Michael Dennis;Jerome Giraudat;Florence Kotzyba-Hibert;Maurice Goeldner

439
Citations
Cellular processing of the nerve growth factor precursor by the mammalian pro-protein convertases.

Nabil G. Seidah;Suzanne Benjannet;Sangeeta Pareek;Diane Savaria

417
Citations
Eukaryotic protein processing: endoproteolysis of precursor proteins.

Nabil G Seidah;Michel Chrétien

401
Citations
Mammalian subtilisin/kexin isozyme SKI-1: A widely expressed proprotein convertase with a unique cleavage specificity and cellular localization

Nabil G. Seidah;Seyed J. Mowla;Josée Hamelin;Aida M. Mamarbachi

391
Citations
Isolation and Amino-acid Sequence of β-LPH from Sheep Pituitary Glands

Choh Hao Li;Livio Barnafi;Michel Chrétien;David Chung

353
Citations
Distribution and regulation of the prohormone convertases PC1 and PC2 in the rat pituitary.

Robert Day;Martin K.H. Schafer;Stanley J. Watson;Michel Chrétien

307
Citations
cDNA structure of the mouse and rat subtilisin/kexin-like PC5: a candidate proprotein convertase expressed in endocrine and nonendocrine cells

J Lusson;D Vieau;J Hamelin;R Day

301
Citations
The secretory proprotein convertases furin, PC5, and PC7 activate VEGF-C to induce tumorigenesis

Geraldine Siegfried;Ajoy Basak;James A. Cromlish;Suzanne Benjannet

300
Citations
cDNA structure, tissue distribution, and chromosomal localization of rat PC7, a novel mammalian proprotein convertase closest to yeast kexin-like proteinases.

N G Seidah;J Hamelin;M Mamarbachi;W Dong

294
Citations
Immunohistochemical Localization of β-Lipotropic Hormone in the Pituitary Gland

G. Pelletier;R. Leclerc;F. Labrie;J. Cote

288
Citations