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Gerard J. M. Martens

Gerard J. M. Martens

D-Index & Metrics

Biology and Biochemistry

D-Index
52
Citations
10305
World Ranking
16639
National Ranking
403

Overview

Gerard J. M. Martens is affiliated with Radboud University in the Netherlands. Their research spans several interconnected fields within the life sciences, focusing primarily on molecular biology, neuroscience, and medicine. Their work contributes to a deeper understanding of the biological mechanisms underlying neurological disorders and neurodegenerative diseases.

Their main fields of study include:

  • Biochemistry, Genetics and Molecular Biology
  • Neuroscience
  • Medicine

Within these disciplines, their research delves into several subfields such as molecular biology, neurology, cellular and molecular neuroscience, immunology, and genetics. This multidisciplinary approach supports investigations into complex biological processes relevant to health and disease.

The scientist's notable areas of focus cover topics like neuroinflammation and neurodegeneration mechanisms, Parkinson's disease mechanisms and treatments, nuclear receptors and signaling, virus-based gene therapy research, RNA interference and gene delivery, neurogenesis and neuroplasticity mechanisms, and RNA research and splicing.

Frequent coauthors in their publications include:

  • Dorien A. Maas
  • Judith R. Homberg
  • Helena Xicoy
  • Kim M. A. De Kleijn
  • Sharon M. Kolk

Their research outputs have appeared in various scientific venues, with multiple publications in journals such as Progress in Neurobiology and the International Journal of Molecular Sciences. Other venues featuring their work include Cellular and Molecular Life Sciences, Nature Communications, and Cells.

Among recent papers authored or coauthored by Gerard J. M. Martens are:

  • Interneuron hypomyelination is associated with cognitive inflexibility in a rat model of schizophrenia, 2020, Nature Communications
  • Explorative Combined Lipid and Transcriptomic Profiling of Substantia Nigra and Putamen in Parkinson's Disease, 2020, Cells
  • White matter structure and myelin-related gene expression alterations with experience in adult rats, 2020, Progress in Neurobiology
  • Histamine-4 receptor antagonist ameliorates Parkinson-like pathology in the striatum, 2020, Brain Behavior and Immunity
  • HGprt deficiency disrupts dopaminergic circuit development in a genetic mouse model of Lesch-Nyhan disease, 2022, Cellular and Molecular Life Sciences

This body of work reflects a strong engagement with neurological disease models, molecular signaling pathways, and gene therapy strategies. Their focus on Parkinson's disease and neuroinflammation underscores a commitment to exploring the biological underpinnings of neurodegenerative conditions and potential therapeutic targets.

Best Publications

  • The SH-SY5Y cell line in Parkinson's disease research: a systematic review

    Helena Xicoy;Bé Wieringa;Gerard J.M. Martens

  • Frameshift Mutants of β Amyloid Precursor Protein and Ubiquitin-B in Alzheimer's and Down Patients

    Fred W. van Leeuwen;Dominique P. V. de Kleijn;Helma H. van den Hurk;Andrea Neubauer

  • Secretory granule biogenesis: rafting to the SNARE.

    Sharon A. Tooze;Gerard J.M. Martens;Wieland B. Huttner

  • 7B2 is a neuroendocrine chaperone that transiently interacts with prohormone convertase PC2 in the secretory pathway.

    Joanna A.M. Braks;Gerard J.M. Martens

  • MicroRNA networks direct neuronal development and plasticity

    N F M Olde Loohuis;A. O. A. Kós;G J M Martens;H van Bokhoven

  • Differential contribution of the three Aph1 genes to γ-secretase activity in vivo

    Lutgarde Serneels;Tim Dejaegere;Kathleen Craessaerts;Katrien Horré

  • The p24 family and selective transport processes at the ER-Golgi interface.

    Jeroen R.P.M. Strating;Jeroen R.P.M. Strating;Gerard J.M. Martens

  • The Role of Lipids in Parkinson’s Disease

    Helena Xicoy;Bé Wieringa;Gerard J. M. Martens

  • Molecular underpinnings of prefrontal cortex development in rodents provide insights into the etiology of neurodevelopmental disorders.

    D Schubert;G J M Martens;S M Kolk

  • The neuroendocrine polypeptide 7B2 is an endogenous inhibitor of prohormone convertase PC2

    Gerard J. M. Martens;Joanna A. M. Braks;Douglas W. Eib;Yi Zhou

  • Expression of the crustacean hyperglycaemic hormones and the gonad-inhibiting hormone during the reproductive cycle of the female American lobster Homarus americanus

    D.P.V. de Kleijn;K.P.C. Janssen;S.L. Waddy;R. Hegeman

  • ATP6AP1 deficiency causes an immunodeficiency with hepatopathy, cognitive impairment and abnormal protein glycosylation.

    Eric J. R. Jansen;Sharita Timal;Margret Ryan;Angel Ashikov

  • Integrated molecular landscape of Parkinson's disease.

    C.J.H.M. Klemann;G.J.M. Martens;M. Sharma;M.B. Martens

  • Cloning and expression of two mRNAs encoding structurally different crustacean hyperglycemic hormone precursors in the lobster Homarus americanus.

    Dominique P.V. de Kleijn;Erik P.H. de Leeuw;Marco C. van den Berg;Gerard J.M. Martens

  • Nucleotide sequence of cloned cDNA for pro-opiomelanocortin in the amphibian Xenopus laevis.

    G J Martens;O Civelli;E Herbert

  • Cloning and expression of mRNA encoding prepro-gonad-inhibiting hormone (GIH) in the lobster Homarus americanus

    Dominique P.V. de Kleijn;Frank J.G.T. Sleutels;Gerard J.M. Martens;François Van Herp

  • Understanding familial and non-familial renal cell cancer

    Daniëlle Bodmer;Wilhelmina van den Hurk;Jan J. M. van Groningen;Marc J. Eleveld

  • Cloning and sequence analysis of human pituitary cDNA encoding the novel polypeptide 7B2.

    Gerard J.M. Martens

  • Cell-autonomous TrkB signaling in presynaptic retinal ganglion cells mediates axon arbor growth and synapse maturation during the establishment of retinotectal synaptic connectivity.

    Sonya Marshak;Angeliki Maria Nikolakopoulou;Ron Dirks;Gerard J. Martens

  • Cloning and expression of two proopiomelanocortin mRNAs in the common carp (Cyprinus carpio L.)

    R.J Arends;H Vermeer;G.J.M Martens;J.A.M Leunissen

Frequent Co-Authors

Eric W. Roubos
Eric W. Roubos Radboud University
Judith R. Homberg
Judith R. Homberg Radboud University
Joost C. M. Holthuis
Joost C. M. Holthuis Osnabrück University
Peter De Weerd
Peter De Weerd Maastricht University
Hans van Bokhoven
Hans van Bokhoven Radboud University
Alexander R. Cools
Alexander R. Cools Radboud University
Dick F. Swaab
Dick F. Swaab Royal Netherlands Academy of Arts and Sciences
Brahim Nait-Oumesmar
Brahim Nait-Oumesmar Institut du Cerveau
Roland P. Kuiper
Roland P. Kuiper Princess Máxima Center
Rob W.J. Collin
Rob W.J. Collin Radboud University

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