World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
62
Citations
18280
World Ranking
10600
National Ranking
764

Research.com Recognitions

  • 2018 - Member of Academia Europaea
  • 2014 - German National Academy of Sciences Leopoldina - Deutsche Akademie der Naturforscher Leopoldina – Nationale Akademie der Wissenschaften Neurosciences
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Frank Bradke is affiliated with the German Center for Neurodegenerative Diseases in Germany. Their research primarily focuses on neuroscience, with significant contributions to biochemistry, genetics, and molecular biology. Their subfields of study include cellular and molecular neuroscience, developmental neuroscience, cell biology, molecular biology, and neurology.

The main topics covered in Frank Bradke's work include:

  • Neurogenesis and neuroplasticity mechanisms
  • Nerve injury and regeneration
  • Axon guidance and neuronal signaling
  • Microtubule and mitosis dynamics
  • Spinal cord injury research
  • Cellular mechanics and interactions
  • Neuroinflammation and neurodegeneration mechanisms

Frequent publication venues for their research are:

  • Neuron
  • Brain Communications
  • Current Opinion in Neurobiology
  • Journal of Visualized Experiments
  • bioRxiv (Cold Spring Harbor Laboratory)

Among recent papers, notable titles include:

  • Therapeutic repair for spinal cord injury: combinatory approaches to address a multifaceted problem, 2020, EMBO Molecular Medicine
  • RhoA drives actin compaction to restrict axon regeneration and astrocyte reactivity after CNS injury, 2021, Neuron
  • An active vesicle priming machinery suppresses axon regeneration upon adult CNS injury, 2021, Neuron
  • Axon Growth of CNS Neurons in Three Dimensions Is Amoeboid and Independent of Adhesions, 2020, Cell Reports
  • Mechanisms of Axon Growth and Regeneration: Moving between Development and Disease, 2022, Journal of Neuroscience

Frequent co-authors collaborating with Frank Bradke include:

  • Sebastián Dupraz
  • Brett J. Hilton
  • Jarred M. Griffin
  • Barbara Schaffran
  • Eissa Alfadil

The scientist has been recognized by several awards and memberships, including:

  • Member of the Academia Europaea (2018)
  • Member of the German National Academy of Sciences Leopoldina - Deutsche Akademie der Naturforscher Leopoldina - Nationale Akademie der Wissenschaften (2014) in Neurosciences
  • Member of the European Molecular Biology Organization (EMBO)

Best Publications

  • Lifeact: a versatile marker to visualize F-actin

    Julia Riedl;Alvaro H. Crevenna;Kai Kessenbrock;Jerry Haochen Yu

  • Three-dimensional imaging of solvent-cleared organs using 3DISCO.

    Ali Ertürk;Klaus Becker;Klaus Becker;Nina Jährling;Nina Jährling;Nina Jährling;Christoph P Mauch

  • Regeneration of Sensory Axons within the Injured Spinal Cord Induced by Intraganglionic cAMP Elevation

    Simona Neumann;Frank Bradke;Marc Tessier-Lavigne;Allan I. Basbaum

  • The Role of Local Actin Instability in Axon Formation

    Frank Bradke;Carlos G. Dotti

  • Microtubule stabilization specifies initial neuronal polarization.

    Harald Witte;Dorothee Neukirchen;Frank Bradke

  • Microtubule Stabilization Reduces Scarring and Causes Axon Regeneration After Spinal Cord Injury

    Farida Hellal;Andres Hurtado;Jörg Ruschel;Kevin C. Flynn

  • Assembly of a new growth cone after axotomy: the precursor to axon regeneration

    Frank Bradke;James W. Fawcett;Micha E. Spira

  • Systemic administration of epothilone B promotes axon regeneration after spinal cord injury

    Jörg Ruschel;Farida Hellal;Kevin C. Flynn;Sebastian Dupraz

  • Disorganized Microtubules Underlie the Formation of Retraction Bulbs and the Failure of Axonal Regeneration

    Ali Ertürk;Farida Hellal;Joana Enes;Frank Bradke

  • Three-dimensional imaging of the unsectioned adult spinal cord to assess axon regeneration and glial responses after injury

    Ali Ertürk;Ali Ertürk;Christoph P Mauch;Farida Hellal;Friedrich Förstner

  • Reducing HDAC6 ameliorates cognitive deficits in a mouse model for Alzheimer's disease.

    Nambirajan Govindarajan;Pooja Rao;Susanne Burkhardt;Susanne Burkhardt;Farahnaz Sananbenesi;Farahnaz Sananbenesi

  • Lifeact mice for studying F-actin dynamics

    Julia Riedl;Kevin C Flynn;Aurelia Raducanu;Florian Gärtner

  • Coordinating Neuronal Actin–Microtubule Dynamics

    Charlotte H. Coles;Frank Bradke

  • Neuronal Polarity: Vectorial Cytoplasmic Flow Precedes Axon Formation

    Frank Bradke;Carlos G Dotti

  • Axon extension occurs independently of centrosomal microtubule nucleation.

    Michael Stiess;Nicola Maghelli;Lukas C. Kapitein;Susana Gomis-Rüth

  • Cdc42 regulates cofilin during the establishment of neuronal polarity

    Boyan K. Garvalov;Kevin C. Flynn;Dorothee Neukirchen;Liane Meyn

  • Establishment of neuronal polarity: lessons from cultured hippocampal neurons.

    Frank Bradke;Carlos G Dotti

  • The role of the cytoskeleton during neuronal polarization.

    Harald Witte;Frank Bradke

  • ADF/Cofilin-Mediated Actin Retrograde Flow Directs Neurite Formation in the Developing Brain

    Kevin C. Flynn;Kevin C. Flynn;Farida Hellal;Dorothee Neukirchen;Sonja Jacob

  • Control of neuronal polarity and plasticity--a renaissance for microtubules?

    Casper C. Hoogenraad;Frank Bradke

Frequent Co-Authors

Armin Blesch
Armin Blesch Indiana University
John L. Bixby
John L. Bixby University of Miami
Cord Brakebusch
Cord Brakebusch University of Copenhagen
Casper C. Hoogenraad
Casper C. Hoogenraad Utrecht University
James R. Bamburg
James R. Bamburg Colorado State University
Walter Witke
Walter Witke University of Bonn
James W. Fawcett
James W. Fawcett University of Cambridge
Vance Lemmon
Vance Lemmon University of Miami
Frank Kirchhoff
Frank Kirchhoff University of Ulm

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