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Anton P. J. Middelberg

Anton P. J. Middelberg

D-Index & Metrics

Chemistry

D-Index
59
Citations
12658
World Ranking
10121
National Ranking
240

Research.com Recognitions

  • 2020 - Fellow, National Academy of Inventors

Overview

Anton P. J. Middelberg is affiliated with the University of Adelaide in Australia. Their research encompasses a variety of topics and fields, with a focus on molecular biology, ecology, materials chemistry, radiology, nuclear medicine and imaging, and oncology.

The scientist's research covers key topics including bacteriophages and microbial interactions, monoclonal and polyclonal antibodies research, protein purification and stability, viral infectious diseases and gene expression in insects, polyomavirus and related diseases, viral gastroenteritis research and epidemiology, and RNA interference and gene delivery.

Frequent publication venues for Middelberg's work include:

  • Trends in Biotechnology
  • Biotechnology and Bioengineering
  • Chemical Engineering Science
  • Journal of Chromatography A
  • ACS Applied Bio Materials

Notable recent papers authored or co-authored by Middelberg include:

  • "Nanoparticle elasticity regulates phagocytosis and cancer cell uptake", 2020, Science Advances
  • "Continuous downstream bioprocessing for intensified manufacture of biopharmaceuticals and antibodies", 2020, Chemical Engineering Science
  • "Stability of Engineered Ferritin Nanovaccines Investigated by Combined Molecular Simulation and Experiments", 2021, The Journal of Physical Chemistry B
  • "Comparative evaluation of integrated purification pathways for bacterial modular polyomavirus major capsid protein VP1 to produce virus-like particles using high throughput process technologies", 2021, Journal of Chromatography A
  • "Immunogenicity and Vaccine Efficacy Boosted by Engineering Human Heavy Chain Ferritin and Chimeric Hepatitis B Virus Core Nanoparticles", 2021, ACS Applied Bio Materials

The scientist frequently collaborates with colleagues such as Jingxiu Bi, Lukas Gerstweiler, Matthew J. Pavlovich, Rolf Van Der Sanden, and Patrick Scheffmann. These partnerships have contributed to multiple publications over several years.

In 2020, Middelberg was recognized as a Fellow of the National Academy of Inventors.

Best Publications

  • Process-scale disruption of microorganisms.

    Anton P.J. Middelberg

  • Nanoparticle synthesis in microreactors

    Chun-Xia Zhao;Lizhong He;Shi Zhang Qiao;Anton P.J. Middelberg

  • Preparative protein refolding

    Anton P.J Middelberg

  • Two-phase microfluidic flows

    Chun-Xia Zhao;Anton P.J. Middelberg

  • Control of fed-batch fermentations.

    Jeongseok Lee;Sang Yup Lee;Sunwon Park;Anton P.J. Middelberg

  • Bioengineering virus‐like particles as vaccines

    Linda H.L. Lua;Natalie K. Connors;Frank Sainsbury;Yap P. Chuan

  • Subcellular compartment targeting of layered double hydroxide nanoparticles

    Zhi Ping Xu;Marcus Niebert;Katharina Porazik;Tara L Walker

  • Poly-L-lysine functionalized large pore cubic mesostructured silica nanoparticles as biocompatible carriers for gene delivery.

    Sandy B Hartono;Wenyi Gu;Freddy Kleitz;Jian Liu

  • The mechanical properties of Saccharomyces cerevisiae.

    Alexander E. Smith;Zhibing Zhang;Colin R. Thomas;Kennith E. Moxham

  • Towards the preparative and large-scale precision manufacture of virus-like particles

    Leonard Keith Pattenden;Anton Pj Middelberg;Marcus Niebert;Daniel I Lipin

  • Nanoparticle elasticity regulates phagocytosis and cancer cell uptake.

    Yue Hui;Xin Yi;David Wibowo;Guangze Yang

  • Reversible active switching of the mechanical properties of a peptide film at a fluid–fluid interface

    Annette F. Dexter;Andrew S. Malcolm;Anton P. J. Middelberg

  • Formulation of Nanoparticles Using Mixing-Induced Nanoprecipitation for Drug Delivery

    Yun Liu;Guangze Yang;Da Zou;Yue Hui

  • Understanding the Effects of Nanocapsular Mechanical Property on Passive and Active Tumor Targeting.

    Yue Hui;David Wibowo;Yun Liu;Rui Ran

  • Molecular insight into conformational transition of amyloid β-peptide 42 inhibited by (-)-epigallocatechin-3-gallate probed by molecular simulations.

    Fu-Feng Liu;Xiao-Yan Dong;Lizhong He;Anton P. J. Middelberg

  • Quantitative characterization of virus-like particles by asymmetrical flow field flow fractionation, electrospray differential mobility analysis, and transmission electron microscopy

    Leonard F. Pease;Daniel I. Lipin;De-Hao Tsai;De-Hao Tsai;Michael R. Zachariah;Michael R. Zachariah

  • The likelihood of aggregation during protein renaturation can be assessed using the second virial coefficient

    Jason G.S. Ho;Anton P.J. Middelberg;Paul Ramage;Hans P. Kocher

  • Peptides As Functional Surfactants

    Annette F. Dexter;Anton P. J. Middelberg

  • On the mechanism of microbial cell disruption in high-pressure homogenisation

    Andrew R. Kleinig;Anton P.J. Middelberg

  • On uniquely determining cell–wall material properties with the compression experiment

    A.E. Smith;K.E. Moxham;A.P.J. Middelberg

Frequent Co-Authors

Michael Pepper
Michael Pepper University College London
Sang Yup Lee
Sang Yup Lee Korea Advanced Institute of Science and Technology
Yan Sun
Yan Sun Tianjin University
Thomas Huber
Thomas Huber Australian National University
Howard A. Chase
Howard A. Chase University of Cambridge
Ranjeny Thomas
Ranjeny Thomas University of Queensland
Denise L. Doolan
Denise L. Doolan Australian Institute of Tropical Health and Medicine
Hans-Joachim Gabius
Hans-Joachim Gabius Ludwig-Maximilians-Universität München
Shi-Zhang Qiao
Shi-Zhang Qiao University of Adelaide
Justin J. Cooper-White
Justin J. Cooper-White University of Queensland

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