World's Best Scientists 2026 revealed!
Georg Halder

Georg Halder

D-Index & Metrics

Molecular Biology

D-Index
58
Citations
25018
World Ranking
2052
National Ranking
26

Overview

Georg Halder is affiliated with KU Leuven in Belgium and has contributed to research primarily in the fields of Biochemistry, Genetics, and Molecular Biology. Their work spans several subfields including Cell Biology, Molecular Biology, Hepatology, Immunology, and Surgery.

Halder's research focuses extensively on the Hippo pathway signaling and YAP/TAZ, covering 22 publications related to this topic. Other main topics addressed in their research include Liver physiology and pathology, Single-cell and spatial transcriptomics, Gene Regulatory Network Analysis, Invertebrate Immune Response Mechanisms, Genetics, Aging, and Longevity in Model Organisms, as well as Cancer-related Molecular Pathways.

The scientist has published in several notable venues, with multiple articles appearing in Cancer Research, and additional publications in bioRxiv (Cold Spring Harbor Laboratory), Molecular Cancer Research, Gastroenterology, and Science.

  • Regeneration Defects in Yap and Taz Mutant Mouse Livers Are Caused by Bile Duct Disruption and Cholestasis (2020, Gastroenterology)
  • Hippo signaling instructs ectopic but not normal organ growth (2022, Science)
  • Initiation of hepatic stellate cell activation extends into chronic liver disease (2021, Cell Death and Disease)
  • Expected and unexpected effects after systemic inhibition of Hippo transcriptional output in cancer (2024, Nature Communications)
  • Single-cell spatial multi-omics and deep learning dissect enhancer-driven gene regulatory networks in liver zonation (2024, Nature Cell Biology)

Frequent co-authors collaborating with Halder include Leticia Sansores-García, Hanne Hillen, Elisabeth Verboven, Iván M. Moya, and Carmen Bravo González-Blas.

  • Cancer Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Molecular Cancer Research
  • Gastroenterology
  • Science

  • Leticia Sansores-García
  • Hanne Hillen
  • Elisabeth Verboven
  • Iván M. Moya
  • Carmen Bravo González-Blas

  • Hippo pathway signaling and YAP/TAZ
  • Liver physiology and pathology
  • Single-cell and spatial transcriptomics
  • Gene Regulatory Network Analysis
  • Invertebrate Immune Response Mechanisms
  • Genetics, Aging, and Longevity in Model Organisms
  • Cancer-related Molecular Pathways

Best Publications

  • Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control

    Bin Zhao;Xiaomu Wei;Weiquan Li;Ryan S. Udan;Ryan S. Udan

  • Induction of ectopic eyes by targeted expression of the eyeless gene in Drosophila

    Georg Halder;Patrick Callaerts;Walter J. Gehring

  • Hippo signaling: growth control and beyond

    Georg Halder;Randy L. Johnson

  • Transduction of mechanical and cytoskeletal cues by YAP and TAZ

    Georg Halder;Sirio Dupont;Stefano Piccolo

  • The two faces of Hippo: targeting the Hippo pathway for regenerative medicine and cancer treatment

    Randy L Johnson;Georg Halder

  • The tumour-suppressor genes NF2/Merlin and Expanded act through Hippo signalling to regulate cell proliferation and apoptosis.

    Fisun Hamaratoglu;Maria Willecke;Maria Willecke;Madhuri Kango-Singh;Riitta Nolo

  • Hippo promotes proliferation arrest and apoptosis in the Salvador/Warts pathway

    Ryan S Udan;Madhuri Kango-Singh;Riitta Nolo;Chunyao Tao

  • Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver

    Li Lu;Ying Li;Ying Li;Soo Mi Kim;Wouter Bossuyt

  • Hippo-YAP/TAZ signalling in organ regeneration and regenerative medicine.

    Iván M. Moya;Georg Halder

  • Muscle LIM protein, a novel essential regulator of myogenesis, promotes myogenic differentiation

    Silvia Arber;Georg Halder;Pico Caroni

  • PAX-6 IN DEVELOPMENT AND EVOLUTION

    Patrick Callaerts;Georg Halder;Walter J. Gehring

  • MAP4K family kinases act in parallel to MST1/2 to activate LATS1/2 in the Hippo pathway

    Zhipeng Meng;Toshiro Moroishi;Violaine Mottier-Pavie;Steven W. Plouffe

  • Modulating F-actin organization induces organ growth by affecting the Hippo pathway

    Leticia Sansores-Garcia;Wouter Bossuyt;Ken Ichi Wada;Shigenobu Yonemura

  • optix Drives the Repeated Convergent Evolution of Butterfly Wing Pattern Mimicry

    Robert D. Reed;Riccardo Papa;Riccardo Papa;Arnaud Martin;Heather M. Hines

  • Eyeless initiates the expression of both sine oculis and eyes absent during Drosophila compound eye development

    Georg Halder;Patrick Callaerts;Susanne Flister;Uwe Walldorf

  • Decoding the regulatory landscape of melanoma reveals TEADS as regulators of the invasive cell state

    Annelien Verfaillie;Hana Imrichova;Zeynep Kalender Atak;Michael Dewaele

  • twin of eyeless, a second Pax-6 gene of Drosophila, acts upstream of eyeless in the control of eye development

    Thomas Czerny;Georg Halder;Urs Kloter;Abdallah Souabni

  • Ultrabithorax regulates genes at several levels of the wing-patterning hierarchy to shape the development of the Drosophila haltere

    Scott D. Weatherbee;Georg Halder;Jaeseob Kim;Angela Hudson

  • Shar-pei mediates cell proliferation arrest during imaginal disc growth in Drosophila.

    Madhuri Kango-Singh;Riitta Nolo;Chunyao Tao;Patrik Verstreken

  • The apical-basal cell polarity determinant Crumbs regulates Hippo signaling in Drosophila

    Chiao Lin Chen;Kathleen M. Gajewski;Fisun Hamaratoglu;Fisun Hamaratoglu;Fisun Hamaratoglu;Wouter Bossuyt

Frequent Co-Authors

Stein Aerts
Stein Aerts KU Leuven
Walter J. Gehring
Walter J. Gehring University of Basel
Russell E. Lewis
Russell E. Lewis University of Padua
Gordon B. Mills
Gordon B. Mills Oregon Health & Science University
Dimitrios P. Kontoyiannis
Dimitrios P. Kontoyiannis The University of Texas MD Anderson Cancer Center
Rui Chen
Rui Chen Capital Medical University
Randy L. Johnson
Randy L. Johnson The University of Texas MD Anderson Cancer Center
Sean B. Carroll
Sean B. Carroll University of Maryland, College Park
Leo A. van Grunsven
Leo A. van Grunsven Vrije Universiteit Brussel

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