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Uffe Birk Jensen

Uffe Birk Jensen

D-Index & Metrics

Biology and Biochemistry

D-Index
62
Citations
13680
World Ranking
10803
National Ranking
115

Overview

Uffe Birk Jensen is affiliated with Aarhus University in Denmark and has contributed extensively to research in biochemistry, genetics, and molecular biology, as well as medicine. Their work spans multiple subfields, including molecular biology, genetics, pathology and forensic medicine, oncology, and neurology.

Their research focuses on key topics such as BRCA gene mutations in cancer, CRISPR and genetic engineering, genetic factors in colorectal cancer, DNA repair mechanisms, genomics and rare diseases, congenital heart defects research, and colorectal cancer screening and detection.

Recent publications include the following papers:

  • Variation in the risk of colorectal cancer in families with Lynch syndrome: a retrospective cohort study, 2021, The Lancet Oncology
  • Characterization of the Cancer Spectrum in Men With Germline BRCA1 and BRCA2 Pathogenic Variants, 2020, JAMA Oncology
  • Breast and Prostate Cancer Risks for Male BRCA1 and BRCA2 Pathogenic Variant Carriers Using Polygenic Risk Scores, 2021, JNCI Journal of the National Cancer Institute
  • The CRISPR/Cas9 Minipig-A Transgenic Minipig to Produce Specific Mutations in Designated Tissues, 2021, Cancers
  • Common Breast Cancer Susceptibility Alleles and the Risk of Breast Cancer for BRCA1 and BRCA2 Mutation Carriers: Implications for Risk Prediction, 2020, UNC Libraries

Frequent publication venues where their work appears include:

  • UNC Libraries
  • Clinical Genetics
  • European Journal of Medical Genetics
  • Scientific Reports
  • Stem Cell Research

They have collaborated regularly with researchers such as Thorkild Terkelsen, Mads Thomassen, Anne-Marie Gerdes, D. Gareth Evans, and Thomas van Overeem Hansen. Collaborative efforts with these coauthors have produced multiple publications contributing to their fields of study.

Best Publications

  • Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

    Stig E. Bojesen;Stig E. Bojesen;Karen A. Pooley;Sharon E. Johnatty;Jonathan Beesley

  • An important role for type III interferon (IFN-lambda/IL-28) in TLR-induced antiviral activity.

    Nina Ank;Marie B. Iversen;Christina Bartholdy;Peter Staeheli

  • Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer.

    Timothy R. Rebbeck;Nandita Mitra;Fei Wan;Olga M. Sinilnikova

  • Manipulation of stem cell proliferation and lineage commitment: visualisation of label-retaining cells in wholemounts of mouse epidermis

    Kristin M Braun;Catherin Niemann;Uffe Birk Jensen;John P Sundberg

  • The spatial relationship between stem cells and their progeny in the basal layer of human epidermis: a new view based on whole-mount labelling and lineage analysis

    Uffe B. Jensen;Sally Lowell;Fiona M. Watt

  • Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer

    Catherine M Phelan;Karoline B Kuchenbaecker;Karoline B Kuchenbaecker;Jonathan P Tyrer;Siddhartha P Kar

  • Immunolocalization of AQP9 in liver, epididymis, testis, spleen, and brain

    M.-L. Elkjær;Z. Vajda;Z. Vajda;L.N. Nejsum;T.-H. Kwon

  • Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.

    Roger L Milne;Roger L Milne;Karoline B Kuchenbaecker;Karoline B Kuchenbaecker;Kyriaki Michailidou;Kyriaki Michailidou;Jonathan Beesley

  • Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk

    Fergus J. Couch;Xianshu Wang;Lesley McGuffog;Andrew Lee

  • Evaluation of polygenic risk scores for breast and ovarian cancer risk prediction in BRCA1 and BRCA2 mutation carriers

    Karoline B Kuchenbaecker;Karoline B Kuchenbaecker;Lesley McGuffog;Daniel Barrowdale;Andrew Lee

  • Modulation of Keratinocyte Gene Expression and Differentiation by PPAR-Selective Ligands and Tetradecylthioacetic Acid

    Majken Westergaard;Jeanette Henningsen;Morten Lyne Svendsen;Claus Johansen

  • Mutational spectrum in a worldwide study of 29,700 families with BRCA1 or BRCA2 mutations

    Timothy R. Rebbeck;Tara M. Friebel;Eitan Friedman;Ute Hamann

  • Immunolocalization of aquaporin-8 in rat kidney, gastrointestinal tract, testis, and airways.

    Marie-Louise Elkjær;Lene N. Nejsum;Veronika Gresz;Tae-Hwan Kwon;Tae-Hwan Kwon

  • GRIN2B encephalopathy: Novel findings on phenotype, variant clustering, functional consequences and treatment aspects

    Konrad Platzer;Hongjie Yuan;Hannah Schütz;Alexander Winschel

  • Functional requirement of aquaporin-5 in plasma membranes of sweat glands

    Lene N. Nejsum;Tae Hwan Kwon;Uffe B. Jensen;Ornella Fumagalli

  • Common Breast Cancer Susceptibility Alleles and the Risk of Breast Cancer for BRCA1 and BRCA2 Mutation Carriers: Implications for Risk Prediction

    Antonis C. Antoniou;Jonathan Beesley;Lesley McGuffog;Olga M. Sinilnikova

  • Side population cells in human and mouse epidermis lack stem cell characteristics

    Charlotte Triel;Malene Eun Vestergaard;Lars Bolund;Thomas Gryesten Jensen

  • A distinct population of clonogenic and multipotent murine follicular keratinocytes residing in the upper isthmus.

    Uffe Birk Jensen;Xiaohong Yan;Charlotte Triel;Seung-Hyun Woo

  • Role of melanoma chondroitin sulphate proteoglycan in patterning stem cells in human interfollicular epidermis.

    James Legg;Uffe B. Jensen;Simon Broad;Irene Leigh

  • Transcriptional regulator PRDM12 is essential for human pain perception

    Ya Chun Chen;Michaela Auer-Grumbach;Shinya Matsukawa;Manuela Zitzelsberger

Frequent Co-Authors

Irene L. Andrulis
Irene L. Andrulis University of Toronto
Mads Thomassen
Mads Thomassen Odense University Hospital
Georgia Chenevix-Trench
Georgia Chenevix-Trench QIMR Berghofer Medical Research Institute
David E. Goldgar
David E. Goldgar University of Utah
Thomas Hansen
Thomas Hansen Copenhagen University Hospital
Katherine L. Nathanson
Katherine L. Nathanson University of Pennsylvania
Esther M. John
Esther M. John Stanford University
Susan M. Domchek
Susan M. Domchek University of Pennsylvania
Fergus J. Couch
Fergus J. Couch Mayo Clinic

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