World's Best Scientists 2026 revealed!
Katherine L. Nathanson

Katherine L. Nathanson

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Best Female Scientists
2025

D-Index & Metrics

Best Female Scientists

D-Index
115
Citations
50539
World Ranking
715
National Ranking
434

Medicine

D-Index
122
Citations
55278
World Ranking
3476
National Ranking
1911

Research.com Recognitions

  • 2025 - Research.com Best Female Scientists Award
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Katherine L. Nathanson is affiliated with the University of Pennsylvania in the United States and has an extensive research portfolio focusing on genetics, molecular biology, and oncology. Their work encompasses a broad range of topics related to cancer genomics, DNA repair mechanisms, and the genetic basis of cancer susceptibility.

Their publication record includes over 314 works in biochemistry, genetics, and molecular biology, with significant contributions to medicine as well. The subfields of study prominently represented in their research are genetics, molecular biology, oncology, cancer research, and surgery.

The main research topics Katherine L. Nathanson has explored include:

  • BRCA gene mutations in cancer
  • Cancer genomics and diagnostics
  • Genetic associations and epidemiology
  • DNA repair mechanisms
  • Nutrition, genetics, and disease
  • Genomics and rare diseases
  • PARP inhibition in cancer therapy

Notable recent publications by Katherine L. Nathanson include:

  • A Population-Based Study of Genes Previously Implicated in Breast Cancer, 2021, New England Journal of Medicine
  • Phase II Study of Maintenance Rucaparib in Patients With Platinum-Sensitive Advanced Pancreatic Cancer and a Pathogenic Germline or Somatic Variant in BRCA1, BRCA2, or PALB2, 2021, Journal of Clinical Oncology
  • Contralateral Breast Cancer Risk Among Carriers of Germline Pathogenic Variants in ATM, BRCA1, BRCA2, CHEK2, and PALB2, 2023, Journal of Clinical Oncology
  • A human breast atlas integrating single-cell proteomics and transcriptomics, 2022, Developmental Cell
  • The Penn Medicine BioBank: Towards a Genomics-Enabled Learning Healthcare System to Accelerate Precision Medicine in a Diverse Population, 2022, Journal of Personalized Medicine

Frequent publication venues for their work include:

  • Journal of Clinical Oncology
  • Cancer Research
  • UNC Libraries
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Genetics in Medicine

Katherine L. Nathanson's collaborations feature several frequent co-authors, including:

  • Susan M. Domchek
  • Esther M. John
  • Julie R. Palmer
  • Christine B. Ambrosone
  • Jeffrey N. Weitzel

The scientist has been recognized as a member of the Association of American Physicians, which reflects their standing within the medical research community.

Best Publications

  • Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF -mutant melanoma

    Gideon Bollag;Peter Hirth;James Tsai;Jiazhong Zhang

  • The tuberous sclerosis complex.

    Peter B Crino;Katherine L Nathanson;Elizabeth Petri Henske

  • T-cell invigoration to tumour burden ratio associated with anti-PD-1 response

    Alexander C. Huang;Michael A. Postow;Michael A. Postow;Robert J. Orlowski;Rosemarie Mick

  • Acquired Resistance to BRAF Inhibitors Mediated by a RAF Kinase Switch in Melanoma Can Be Overcome by Cotargeting MEK and IGF-1R/PI3K

    Jessie Villanueva;Adina Vultur;John T. Lee;Rajasekharan Somasundaram

  • Low-penetrance susceptibility to breast cancer due to CHEK2(*)1100delC in noncarriers of BRCA1 or BRCA2 mutations

    Hanne Meijers-Heijboer;Ans van den Ouweland;Jan Klijn;Marijke Wasielewski

  • Rare cell variability and drug-induced reprogramming as a mode of cancer drug resistance

    Sydney M. Shaffer;Margaret C. Dunagin;Stefan R. Torborg;Eduardo A. Torre

  • Gene-Panel Sequencing and the Prediction of Breast-Cancer Risk

    Douglas Frederick Easton;Paul David Pharoah;Antonis C. Antoniou;Marc Derek Tischkowitz

  • Cancer Risk Estimates for BRCA1 Mutation Carriers Identified in a Risk Evaluation Program

    Marcia S. Brose;Timothy R. Rebbeck;Kathleen A. Calzone;Jill E. Stopfer

  • Sorafenib in advanced melanoma: a Phase II randomised discontinuation trial analysis

    T Eisen;T Ahmad;K T Flaherty;M Gore

  • Network modeling links breast cancer susceptibility and centrosome dysfunction.

    Miguel Angel Pujana;Jing Dong J Han;Lea M. Starita;Kristen N. Stevens

  • Pathology of Breast and Ovarian Cancers among BRCA1 and BRCA2 Mutation Carriers: Results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA).

    Nasim Mavaddat;Daniel Barrowdale;Irene L. Andrulis;Susan M. Domchek

  • PTEN Mutation Spectrum and Genotype-Phenotype Correlations in Bannayan-Riley-Ruvalcaba Syndrome Suggest a Single Entity With Cowden Syndrome

    Debbie J. Marsh;Debbie J. Marsh;Jennifer B. Kum;Jennifer B. Kum;Kathryn L. Lunetta;Michael J. Bennett

  • Comprehensive Molecular Characterization of Pheochromocytoma and Paraganglioma

    Lauren Fishbein;Lauren Fishbein;Ignaty Leshchiner;Ignaty Leshchiner;Vonn Walter;Vonn Walter;Ludmila Danilova;Ludmila Danilova

  • Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

    Stig E. Bojesen;Stig E. Bojesen;Karen A. Pooley;Sharon E. Johnatty;Jonathan Beesley

  • PTEN loss confers BRAF inhibitor resistance to melanoma cells through the suppression of BIM expression

    Kim H.T. Paraiso;Yun Xiang;Vito W. Rebecca;Ethan V. Abel

  • Metastatic potential of melanomas defined by specific gene expression profiles with no BRAF signature.

    Keith S Hoek;Natalie C Schlegel;Patricia Brafford;Antje Sucker

  • A Population-Based Study of Genes Previously Implicated in Breast Cancer

    Chunling Hu;Steven N Hart;Rohan Gnanaolivu;Hongyan Huang

  • HIF-α Effects on c-Myc Distinguish Two Subtypes of Sporadic VHL-Deficient Clear Cell Renal Carcinoma

    John D. Gordan;Priti Lal;Vijay R. Dondeti;Richard Letrero

  • A single dose of neoadjuvant PD-1 blockade predicts clinical outcomes in resectable melanoma

    Alexander C. Huang;Robert J. Orlowski;Robert J. Orlowski;Xiaowei Xu;Rosemarie Mick

  • Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer.

    Timothy R. Rebbeck;Nandita Mitra;Fei Wan;Olga M. Sinilnikova

Frequent Co-Authors

Susan M. Domchek
Susan M. Domchek University of Pennsylvania
Fergus J. Couch
Fergus J. Couch Mayo Clinic
Kenneth Offit
Kenneth Offit Memorial Sloan Kettering Cancer Center
Douglas F. Easton
Douglas F. Easton University of Cambridge
Irene L. Andrulis
Irene L. Andrulis University of Toronto
Esther M. John
Esther M. John Stanford University
Georgia Chenevix-Trench
Georgia Chenevix-Trench QIMR Berghofer Medical Research Institute
Susan L. Neuhausen
Susan L. Neuhausen City Of Hope National Medical Center
Jeffrey N. Weitzel
Jeffrey N. Weitzel Natera (United States)

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